Lifeboat Foundation

Mentions aging!

Obesity affects more than 40 percent of adults in the United States and 13 percent of the global population. With obesity comes a variety of other interconnected diseases including cardiovascular disease, diabetes, and fatty liver disease, which makes the disease one of the most difficult—and most crucial—to treat.

“Obesity is the biggest health problem in the United States. But, it is hard for people to lose weight and keep it off; being on a diet can be so difficult. So, a pharmacological approach, or a drug, could help out and would be beneficial for all of society,” said Webster Santos, professor of chemistry and the Cliff and Agnes Lilly Faculty Fellow of Drug Discovery in the College of Science at Virginia Tech.

Continue reading “Drug researcher develops ‘fat burning’ molecule that has implications for treatment of obesity” »

In this new installment of our series on the highest-mileage Tesla Model X (and one of the highest mileage EVs in the world), we look into battery degradation and replacement on a Tesla with over 400,000 miles.

Earlier this year, I bought one of the cheapest and most high-mileage Tesla Model X vehicles ever.

Continue reading “A look at Tesla battery degradation and replacement after 400,000 miles” »

This work on one-cell embryos could advance our knowledge of the mechanisms that underpin cellular behaviour in general, and may ultimately provide insights into what goes wrong in aging and disease.

For the first time, scientists have added microscopic tracking devices into the interior of cells, giving a peek into how development starts.

Rapamycin, a drug that has life-extending effects on mice (and possibly dogs and humans), also reverses age-related dental problems in mice. 🦷 Out now in eLife from researchers at The University of Washington School of Dentistry & JAX’s Kaczorowski Lab:

Rapamycin, which has life-extending effects on mice, also reverses age-related dental problems such as periodontitis and regrows bones in the animals.

#Eternal life might not be attainable in the near future, but genetic engineers and doctors are working on new life extension technology. The research could lead to keeping our bodies young, and scientists are developing ways of downloading our brain’s consciousness onto digital media once the body is at the end of its life cycle.

#RT #Documentary offers you in-depth documentary films on topics that will leave no one indifferent. It’s not just front-page stories and global events, but issues that extend beyond the headlines. Social and environmental issues, shocking traditions, intriguing personalities, history, sports and so much more – we have documentaries to suit every taste. RTD’s film crews travel far and wide to bring you diverse and compelling stories. Discover the world with us!

Continue reading “Chasing immortality | The Future is Now” »

SEE MORE EPISODES like this https://podcast.hyperwellbeing.com/

In this fifteenth episode, Liz Parrish shares her quest for radical life extension and details her two completed gene therapies. She describes the regenerative medical tourism available today for increased lifespan and costs. She relates her company’s mission to create a human that regenerates faster than they degenerate. She details her upcoming gene therapies, including upgraded IQ.

Continue reading “Genetically Modifying Humans to Reverse Aging — Today – EP15: Liz Parrish (BioViva)” »

Ira Pastor, ideaXme life sciences ambassador, interviews Dr. Eric Van Gieson, Program Manager in the Biological Technologies Office (BTO) at DARPA. https://www.darpa.mil/staff/dr-eric-van-gieson

Ira Pastor Comments

Continue reading “Optimising Performance of the Human Body and Mind with Defense Advanced Research Projects” »

A study by Monash Biomedicine Discovery Institute (BDI) expands the understanding of the molecular pathways that control T cell function and survival and how it relates to declining T cell immunity in the elderly.

The findings, published in Nature Communications, led by Monash BDI’s Professor Nicole La Gruta and Dr. Kylie Quinn (formerly of Monash University BDI, now Vice-Chancellor’s Research Fellow at RMIT University), outline that the increased metabolism of T cells observed with advanced age was an indication that they were working harder merely to survive.

This contradicts previous knowledge, which suggested an increased metabolism was indicative of T cell function, and will have implications for the development of targeted interventions such as vaccines or immunotherapies to treat age-related immune dysfunction.

Undifferentiated human stem cells have been coaxed to develop into skin-like structures in vitro. When engrafted onto mice, the structures produce hair — highlighting the potential of the approach for regenerative therapies. Hair-follicle organoids that have a full complement of skin cells.