Lifeboat Foundation

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Longtermism asks fundamental questions and promotes the kind of consequentialism that should guide public policy.

Based on a talk delivered at the conference on Existential Threats and Other Disasters: How Should We Address Them? May 30–31, 2024 – Budva, Montenegro – sponsored by the Center for the Study of Bioethics, The Hastings Center, and The Oxford Uehiro Center for Practical Ethics.

Continue reading “Are Children The Future?: Longtermism, Pronatalism, and Epistemic Discounting” »

For over five decades, futurist Raymond Kurzweil has shown a propensity for understanding how computers can change our world. Now he’s ready to anoint nanorobots as the key to allowing humans to transcend life’s ~120-year threshold.

As he wrote—both in the upcoming The Singularity is Nearer book (set for release on June 25) and in an essay published in Wired —the merging of biotechnology with artificial intelligence will lead to nanotechnology helping “overcome the limitations of our biological organs altogether.”

As our bodies accumulate errors when cells reproduce over and over, it invites damage. That damage can get repaired quickly by young bodies, but less so when age piles up.

Researchers in Budapest have been studying worms to slow down or stop ageing in humans by researching transposable elements in our DNA.

Harvanek ZM, Fogelman N, Xu K, Sinha R. Psychological and biological resilience modulates the effects of stress on epigenetic aging. Transl Psychiatry. 2021;11:1–9.

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Scientists have discovered that CAR T cells, traditionally used in cancer treatment, can be engineered to fight aging by eliminating senescent cells, offering a promising single-dose, lifelong treatment against aging-related diseases.

The fountain of youth has eluded explorers for ages. It turns out the magic anti-aging elixir might have been inside us all along.

Cold Spring Harbor Laboratory (CSHL) Assistant Professor Corina Amor Vegas and colleagues have discovered that T cells can be reprogrammed to fight aging, so to speak. Given the right set of genetic modifications, these white blood cells can attack another group of cells known as senescent cells. These cells are thought to be responsible for many of the diseases we grapple with later in life.

Centenarians, once considered rare, have become commonplace. Indeed, they are the fastest-growing demographic group of the world’s population, with numbers roughly doubling every ten years since the 1970s.

How long humans can live, and what determines a long and healthy life, have been of interest for as long as we know. Plato and Aristotle discussed and wrote about the ageing process over 2,300 years ago.

The pursuit of understanding the secrets behind exceptional longevity isn’t easy, however. It involves unravelling the complex interplay of genetic predisposition and lifestyle factors and how they interact throughout a person’s life.

Join us on Patreon! https://www.patreon.com/MichaelLustgartenPhDDiscount Links: Epigenetic, Telomere Testing: https://trudiagnostic.com/?irclickid=U-s3Ii2r7x…

The DNA a woman is born with may influence how her cells respond to chromosomal abnormalities acquired with aging, according to a new genomic analysis co-led by NCI researchers.

Vitamin D extended the lifespan of killifish, a recent study found, suggesting the vitamin could have similar effects in humans.