Lifeboat Foundation

Recently, Libella Gene Therapeutics has announced that it will be running a patient-paid trial in Colombia with an eye-watering $1 million USD price tag on enrollment.

Patient-paid trial likely to cause backlash

The topic of patient-paid trials often stirs up considerable debate among the research community, regulatory authorities, and the general public, with many people suggesting that it is unethical to expect patients to pay to participate in clinical trials. While this is a controversial issue, these trials are a legitimate way to test therapies that would otherwise struggle to reach the clinic due to cost constraints, and the data gathered by such trials can still be valuable.

The study saw the deployment of a multiple target gene therapy focused on 3 known longevity genes delivered via an adeno-associated virus. The focus was on mitigating T2 diabetes, heart failure, and kidney failure in mouse models with very positive results observed. Join us on Tuesday, 26th November, 1pm EDT on our Facebook page for the livestream show.

Just one million dollars.

MANHATTAN, Kan., Nov. 21, 2019 /PRNewswire/ — Libella Gene Therapeutics, LLC (“Libella”) announces an institutional review board (IRB)-approved pay-to-play clinical trial in Colombia ( South America ) using gene therapy that aims to treat and ultimately cure aging. This could lead to Libella offering the world’s only treatment to cure and reverse aging by 20 years.

A team of scientists at the University of Antwerp (Belgium) wants to stop the aging process. They are fascinated by uncovering longevity signatures at the tiny molecular level and are developing an intelligent nanomachine that lays the foundations for new therapies against aging and chronic diseases. Only ten conditions cause 75% of all mortalities. The top three of cardiovascular disease, diabetes, and cancer accounts for 50% of all mortalities. Are these chronic diseases age-related? Can we address them by targeting aging?

A new study finds that gut bacteria from old mice can help rejuvenate the neurons of younger ones, suggesting that gut bacteria are key to aging.

Chemotherapy-treated cancer cells that enter a non-dividing state called senescence can nevertheless boost cancer growth. The finding that these cells eat neighbouring cells reveals a mechanism that enables senescent cells to persist. Chemotherapy-treated tumours boost their survival by ingesting cells.

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Increases in life span are one of the greatest success stories of modern society. Yet, while most of us can expect to live longer, we are spending more years in ill health. Reducing this period of ill health at the end of life is the main aim of a group of scientists known as biogerontologists.

By studying aging in animals, including fruit flies, worms, and rodents, biogerontologists have identified biological phenomena involved with aging that all these organisms share. And some of these biological processes may also regulate aging in humans.

Scientists attempting to understand and improve the aging process have identified many molecules that appear to improve aging in these animals (although evidence in humans remains scant). These molecules include compounds found in grapes, apples, and even bacteria.