Lifeboat Foundation

German scientists are researching a method to produce hydrogen using light and photoactive compounds on an organic chemical basis.

Hydrogen is considered to be one of the alternative energy sources of the future. So far, however, the costly and energy-intensive production process has been a major problem with regard to the environmental friendliness of this substance, which is in itself CO₂ neutral. For this reason, increasing numbers of scientists around the world are researching other methods of producing hydrogen: from algae, for example. (IO reported). Scientists in Germany at the Friedrich Schiller University, the Leibniz Institute for Photonic Technologies (Leibniz IPHT) and the University of Ulm have taken inspiration from nature for their method of producing hydrogen.

To do so, the team from the “CataLight” Collaborative Research Center at the Universities of Jena and Ulm has combined new organic dyes with non-precious metal catalyst molecules that release gaseous hydrogen in water when irradiated with light. This substitute has shown a remarkable impact in terms of longevity and effect after excitation by visible light, they write in their study, published in Chemistry – A European Journal.

Continue reading “Hydrogen production with artificial photosynthesis and polymers” »

Here’s my latest video!

The Hallmarks of Aging are well established, but what is less discussed is the impact of microbes and/or microbial products. The bacterial metabolite, LPS, increases during aging, and it negatively impacts mitochondrial function, thereby demonstrating a role for microbial products on one of the Hallmarks of Aging, mitochondrial dysfunction.

I am sure you know weak bones break more easily, and the older you get the worse any extended periods of inactivity are, on not just your present health and well being, but also your longevity.

So whether you are lifting free weights for the fun of it, using your body weight in a home scenario or engaging in daily activities you know are physically taxing, you should really be incorporating some form of strength training in your plans for longevity.

Get your copy of Cyberpunk 2077 here:
http://cyberpunk.net/buy.

Sources & further reading:
https://sites.google.com/view/sources-mindupload.

Continue reading “Can You Upload Your Mind & Live Forever? feat. Cyberpunk 2077” »

We interviewed a group of Russian biohackers who performed a plasma dilution experiment on themselves. This experiment, the first of its kind, was based on previous mouse studies by Drs. Irina and Michael Conboy.

Some molecules, while essential for various body functions, can be harmful when overproduced. Inflammatory cytokines, such as transforming growth factor beta 1 (TGF-ß1), interleukin 6 (IL6), and tumor necrosis factor alpha (TNFa) are good examples. The concentration of these cytokines in our blood rises with age, provoking inflammaging, the chronic inflammation that is associated with aging. It has been long speculated that reducing the harmful molecules in circulation can attenuate aging.

Nice lecture with both technical info and analogy.

Latest study from David Sinclair’s lab have used cellular reprogramming to restore vision in aged mice & more! Suggests reversing aging *may* be possible.

Continue reading “Reversing aging through cellular reprogramming!?” »

Dr. Steve Horvath, a professor of genetics and biostatistics at UCLA, has found a way to measure biological aging – a type of “clock” – based on the methylation pattern of an organism’s genome. Methylations are biochemical processes that modify the activity of a DNA segment without changing its sequence – a type of epigenetic change. This video primer explains the basics of epigenetic clocks, the topic of our interview with Dr. Steve Horvath, coming soon!

Get the show notes here:
https://www.foundmyfitness.com/episodes/epigenetic-clock/

Continue reading “Epigenetic Aging: How old is your DNA?” »

A questionnaire developed by XPRIZE and Deep Longevity claims to be able to accurately predict your psychological age by using artificial intelligence (AI) to analyze your answers, which theoretically should fall close to your chronological age. The questionnaire is developed from a study published in Aging that used AI in an attempt to identify key hallmarks of psychological aging and the top risk factors that affect mortality.

While the questionnaire seems like a fun insight into whether you’re an old soul or a young gun at heart, there is an important scientific basis for an age-predicting AI. The newly developed technology represents the first AI aimed solely at using psychological aspects to predict age. The researchers hope it can contribute to understanding the role psychological clocks play in overall aging, as well as improving mental health and the feeling of youth.

“For the first time, AI can predict human psychological and subjective age and help identify the possible interventions that can be applied in order to help people feel and behave younger,” said Alex Zhavoronkov, PhD, founder and CLO of Deep Longevity and co-author of the study, in a statement.

A new study has found that a novel T cell genetically engineered by University of Arizona Health Sciences researchers is able to target and attack pathogenic T cells that cause Type 1 diabetes, which could lead to new immunotherapy treatments.

The immune system fights bacteria, viruses and other pathogens by utilizing several types of T cells, all of which have receptors that are specific to particular antigens. On killer T cells, the receptor works in concert with three signaling modules and a coreceptor to destroy the infected cell. Michael Kuhns, Ph.D., an associate professor in the UArizona College of Medicine—Tucson Department of Immunobiology, copied the evolutionary design to engineer a five-module chimeric antigen receptor, or 5MCAR, T cell.

“The 5MCAR was an attempt to figure out if we could build something by biomimicry, using some of evolution’s natural pieces, and redirect T cells to do what we want them to do. We engineered a 5MCAR that would direct killer T cells to target autoimmune T cells that mediate Type 1 diabetes,” said Dr. Kuhns, who is member of the UArizona Cancer Center, BIO5 Institute and Arizona Center on Aging. “So now, a killer T cell will actually recognize another T cell. We flipped T cell-mediated immunity on its head.”