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Archive for the ‘life extension’ category: Page 232

Mar 22, 2021

Why Do We Age? 4 Theories of Aging

Posted by in category: life extension

Scientists don’t actually agree on why we age (which I find a little wild), but there are a number of competing theories of aging.

I dug into 4 of the most representative and current. Any ones you’d add?:


Why do we age? Lots of theories have tried to explain the aging process, but the truth is scientists still don’t agree on a single reason.

Mar 21, 2021

Liz Parrish goes deep into gene therapies at the HackMyAge Podcast by Zora (March 2021)

Posted by in categories: biotech/medical, computing, genetics, law, life extension, neuroscience

Long but annotated! Most important here is human data for specific treatments due out starting in May or June. And apparently they had a mouse study where they expected a paper due out already but other groups chimed in to help with more testing so there is a delay.


Liz Parrish, CEO of BioViva Science and patient zero of biological rejuvenation with gene therapies, is interviewed by Zora Benhamou on her fresh podcast “HackMyAge”.

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Mar 21, 2021

HDL Update: Age-Related Changes, All-Cause Mortality Risk, And Progress Towards The Optimal Range

Posted by in categories: biotech/medical, life extension, sex

Here’s my latest video!


In November 2020, I made a HDL video based on a meta-analysis in ~3.4 million subjects that was published in July 2020. In Dec 2020, a larger study (n=15.8 million subjects) was published-those data are presented in the video, and compared against the meta-analysis.

Continue reading “HDL Update: Age-Related Changes, All-Cause Mortality Risk, And Progress Towards The Optimal Range” »

Mar 20, 2021

New technology ‘retrains’ cells to repair damaged brain tissue in mice after stroke

Posted by in categories: bioengineering, biotech/medical, genetics, life extension, neuroscience

The regeneration of damaged central nervous system (CNS) tissues is one of the biggest goals of regenerative medicine.


Most stroke victims don’t receive treatment fast enough to prevent brain damage. Scientists at The Ohio State University Wexner Medical Center, College of Engineering and College of Medicine have developed technology to “retrain” cells to help repair damaged brain tissue. It’s an advancement that may someday help patients regain speech, cognition and motor function, even when administered days after an ischemic stroke.

Engineering and medical researchers use a process created by Ohio State called tissue nanotransfection (TNT) to introduce genetic material into cells. This allows them to reprogram skin cells to become something different—in this case vascular cells—to help fix damaged tissue.

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Mar 20, 2021

U.S. Transhumanist Party Virtual Enlightenment Salon with Aubrey de Grey

Posted by in categories: biotech/medical, geopolitics, life extension, transhumanism

Today at 1 PM PST.


On Sunday, February 212021, at 1 p.m. U.S. Pacific Time, the U.S. Transhumanist Party invites Dr. Aubrey de Grey of the SENS Research Foundation, for an in-depth conversation about recent developments in the quest to reverse the damage of biological aging. The discussion will cover current in rejuvenation research and advocacy, as well as delve into how the prospects for reaching longevity escape velocity have changed since Dr. de Grey’s remarks at the U.S. Transhumanist Party Discussion Panel on Life Extension nearly 4 years ago in 2017.

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Mar 20, 2021

An End To Aging — The Mother Of All Disease

Posted by in categories: biotech/medical, life extension, neuroscience

I will look at the idea that all disease could be almost stopped in its tracks with a universal treatment for aging. A lot of people ask when we will cure aging and the answer is it may well be here sooner than many realise.

It doesn’t matter how good the treatments are that we develop for cancer, heart disease, alzheimers, and any other of a number of the most common ways we finally die, it is really just a game of whack a mole. If you survive one, just wait a few years and another will get you.

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Mar 19, 2021

The Last Generation to Die

Posted by in categories: biotech/medical, life extension

Biomedical gerontologist Aubrey de Grey, who’s Chief Science Officer of the SENS Research Foundation, is now predicting a 50% chance that people will begin retaining their youthful state via advanced science and technologies by the year 2036.

This is roughly around the same timeline that The Last Generation to Die is based on. Nailed it (hopefully)!

Mar 19, 2021

Biomedical gerontologist Aubrey de Grey

Posted by in categories: biotech/medical, life extension

who’s Chief Science Officer of the SENS Research Foundation, is now predicting a 50% chance that people will begin retaining their youthful state via advanced science and technologies by the year 2036.

This is roughly around the same timeline that The Last Generation to Die is based on. Nailed it (hopefully)!

Mar 18, 2021

Ageing: Looming crisis or booming opportunity?

Posted by in categories: economics, government, life extension

https://youtube.com/watch?v=m0vWME0Mk1Q

By 2050, the number of adults over the age of 65 globally will double, reaching a staggering 1.6 billion, with the largest growth in the developing world. This growth will be one of the greatest social, economic, and political transformations of our time, that will impact existing healthcare, government and social systems, that today are largely not inclusive of the ageing population or built to the scale needed to support it.

But we can begin to make investments in our support systems (enabled and scaled by technology) that encompass a coordinated response from governments, society, academia, and the private sector.

Continue reading “Ageing: Looming crisis or booming opportunity?” »

Mar 17, 2021

Metformin Mechanism Of Action

Posted by in categories: biotech/medical, computing, life extension

Following in my recent series on subjects that are all the rage in anti-aging and longevity circles, to help you get a good grasp of the essentials so you can know what all the talk is about, and can make informed judgements rather than just following the herd blindly. This time it is on Metformin. This is a drug widely known as a diabetes drug and it has been in use for a very long time, indeed it is one of the most prescribed drugs there is. Recently it has also been a buzz word in the anti aging/longevity communities following the review of data and with it s mechanism of action, being touted and recommended by a variety of voices in the public domain. But how does it work, and how could it improve longevity? Is it safe? Well, if you want to go into a bit more depth and know all the details, I have put together a video which helps you understand what all the fuss is about. And whatever you are doing, have a great day.


Metformin is very popular in the anti aging paradigm currently so let’s have a look at what it is, what it offers, and what the trade offs are… because, well, it is always wise to have all the data.

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