https://www.youtube.com/watch?v=n9IxomBusuw.
Key points of the 2hrs+ long interview between dr. Andrew Huberman and dr. David Sinclair.
Reprogramming without having to insert genes.
When people think of cellular reprogramming, converting a differentiated cell into a stem cell, they often refer to the overexpression of Yamanaka factors[Oct4, Klf4, Sox2 & c-Myc]. Rightly so. But what if i told you that stem cells could be induced with just chemicals. Well you would reply “show me the data”. So, let’s take a look at this recent Nature paper that showed how combinations of small molecules/chemicals converted human differentiated cells to stem cells.
“The Price of Immortality” is a balanced and fluent account of the diverse movement to make humans immortal https://econ.trib.al/wGM2Vwu
Credit: Murray Ballard.
Incredible and somewhat frightening visions of the future will become a reality in the coming decades. According to futurologists, people of the future will gain immortality and will live in the body of a machine. Dr. Ian Pearson predicts that a person will be able to transfer his mind into a computer and one day he will go to a funeral where his previous biological body will be buried. Like anomalien.com on Facebook To stay in touch & get our latest news Cyborgization has some good sides. Let us take into account that we will be able to exchange each of…
Voyager 1 is the farthest human-made object from Earth. After sweeping by Jupiter, Saturn, Uranus and Neptune, it is now almost 15 billion miles (24 billion kilometers) from Earth in interstellar space. Both Voyager 1 and its twin, Voyager 2, carry little pieces of humanity in the form of their Golden Records. These messages in a bottle include spoken greetings in 55 languages, sounds and images from nature, an album of recordings and images from numerous cultures, and a written message of welcome from Jimmy Carter, who was U.S. president when the spacecraft left Earth in 1977.
The Golden Records were built to last a billion years in the environment of space, but in a recent analysis of the paths and perils these explorers may face, astronomers calculated that they could exist for trillions of years without coming remotely close to any stars.
Having spent my career in the field of religion and science, I’ve thought a lot about how spiritual ideas intersect with technological achievements. The incredible longevity of the Voyager spacecraft presents a uniquely tangible entry point into exploring ideas of immortality.
The field of female reproductive longevity and inequality is getting more and more attention. In fact, it is one of the hottest areas of the emerging longevity biotechnology industry, and every venture firm in the field is either investing, incubating, or looking for projects in this area. Companies like BOLD Capital, Future Ventures, LongeVC, and iconic biotechnology investors including Bob Nelsen and Christian Angermayer, are all active and significant partners in this area of science. While females generally live longer than men, their reproductive period is limited—something that is often overlooked. A female’s peak reproductive years are between the late teens and late 20s. Fertility starts to decline by age 30, and this decline becomes more rapid once women reach the mid-30s. By 45, fertility declines so much that getting pregnant naturally is unlikely for most women. Likewise, women begin life with a fixed number of eggs in their ovaries, usually around one million. This number decreases as women age. Ovaries age faster than the rest of a woman’s body—an understudied phenomenon of a neglected organ. None of us would be here without them. Yet surprisingly little is known about the avocado-shaped organ that’s nestled inside half of all humans.
The ovaries also influence a woman’s overall health and well-being. This includes how they age, since this organ tends to lose its function with age faster than any other tissue. This is called asynchronous aging, and it’s one reason why a woman’s fertility declines, and menopause strikes, while they are still relatively young.
In one of my previous articles, I wrote about Gameto, a biotechnology company that is translating the impact of ovarian aging to develop solutions to improve fertility and stop the impact of menopause on female health. Gameto’s co-founder and CEO Dina Radenkovic told me about her intention to redefine the narrative around female reproductive longevity and making it more around health and longevity. Gameto is building a platform for ovarian therapeutics to address menopause and improve assisted fertility. Dina told me she hopes it will make women suffer fewer health problems in their later lives. Neglecting the ovaries—except for their crucial role in IVF treatments—has been part of a general disregard for many aspects of women’s health in the biomedical world.
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Levine’s Biological age calculator is embedded as an Excel file in this link from my website:
https://michaellustgarten.com/2019/09/09/quantifying-biological-age/
Continue reading “Quantifying Biological Age: Blood Test #3 in 2022” »
In this episode of Longevity by Design, our hosts, Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, are joined by Dr. George Church, Professor of Genetics at Harvard Medical School. Tune in as Dr. George Church discusses the many roles of gene therapy, including its ability to reverse age-related diseases.
For science-backed ways to live a healthier, longer life, download InsideTracker’s InnerAge eBook at insidetracker.com/podcast.
Continue reading “Dr. George Church—Gene Therapy and Aging” »
Summary: Researchers used optogenetics techniques to stimulate specific brain areas to increase neurogenesis and the production of neural stem cells to improve memory, cognition, and emotional processing in animal models.
Source: UNC Health Care.
We humans lose mental acuity, an unfortunate side effect of aging. And for individuals with neurodegenerative conditions such as Alzheimer’s and Parkinson’s, the loss of cognitive function often accompanied by mood disorders such as anxiety is a harrowing experience. One way to push back against cognitive decline and anxiety would be to spur the creation of new neurons.
