Lifeboat Foundation

Estimates put this industry’s worth at a staggering $610 billion by 2025. 😳

The Renaissance philosopher Montaigne quipped that “death has us by the scruff of the neck at every moment.” He could have added: until, finally, it strangles us. But what if we knew how to escape death’s chokehold? What if we could avoid death and live forever?

Immortality might seem like the stuff of science fiction, yet it’s increasingly becoming the focus of real science. In 2013, Google launched Calico, a biotech firm whose objective is to “solve” death. PayPal co-founder Peter Thiel, meanwhile, has pledged to “fight” death. And last year, it was reported Amazon chairman Jeff Bezos had invested in Altos Labs, a company that plans to “rejuvenate” cells in order to “reverse disease.” (Bezos owns The Washington Post.)

Continue reading “The long and gruesome history of people trying to live forever” »

Not an amazing update. All female rats are not getting the results the previous group of males got. To my knowledge human trials are still actively being set up for late this year.

In this video we report on the May 2022 update from Dr. Katcher’s experiment with E5, where he is testing to see how long the rats will stay alive if they are given an E5 injection every 90 days.

Continue reading “Dr Katcher’s E5 Experiment May 2022 Update | Review” »

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Papers referenced in the video:
Life-Span Extension in Mice by Preweaning Food Restriction and by Methionine Restriction in Middle Age.
https://pubmed.ncbi.nlm.nih.gov/19414512/

Continue reading “Methionine Restriction Extends Lifespan-What’s Optimal For Protein Intake? n=1 Analysis” »

Earlier this month, we brought you the news that epigenetic reprogramming startup YouthBio Therapeutics had emerged from stealth. The company shed some light on its plans to develop epigenetic reprogramming therapies for age-related diseases by rejuvenating certain cells in our bodies. YouthBio aims to achieve this rejuvenation by developing gene therapies that enable partial cellular reprogramming – an area of longevity science that is now attracting significant commercial interest.

Longevity. Technology: Cellular reprogramming refers to the process of returning adult cells to a “pluripotent” state: blank, embryonic-like cells that can become any cell in the body. This reprogramming can be achieved using techniques based on the discovery of Yamanaka factors.

Scientists led by Dr. Manuel Serrano have observed symptoms of rejuvenation in the pancreas, liver, spleen, and blood of mice after applying one cycle of cell reprogramming.

To achieve this, the researchers have characterized rejuvenation by studying molecular marks in the DNA, gene expression, and cell metabolism. The study has been published in the journal Aging Cell.

Continue reading “Researchers Rejuvenate Mouse Organs Through Cellular Reprogramming” »

With an aging global population, time is of the essence to find novel targets and therapies for age-related diseases.

A research team from Osaka University in Japan has concluded that a clinical trial of transplanted IPS cell-derived corneal tissue was safe and effective – further evidence that cellular reprogramming with Yamanaka factors is moving towards scalable therapies.

Longevity. Technology: The clinical trial spanned several years and used corneal tissues derived from induced pluripotent stem cells. The tissue was transplanted into four almost-blind patients, and, according to the research team, none of the patients experienced rejection or tumorigenicity of the transplanted cells and all saw improvements in their symptoms, with three experiencing improved eyesight, with one improving from 0.15 to 0.7. Importantly, all were free of side effects one year later.

IPS cells can be generated from any adult cell, with Yamanaka factors – a group of protein transcription factors from four master genes. These induced stem cells demonstrate the significant quality of pluripotency – they can differentiate into all other cell types of the body. This is incredibly useful both for research and for therapy.

Sun, Sep 11 at 12 PM CDT.

This is an invitation to the Annual General Meeting of the Cryonics Institute & the Immortalist Society.

The Cryonics Institute’s Annual General Meeting (AGM) will be held on Sunday, September 11th 2022 from 3:00pm to 6:30pm at the Infinity Hall & Sidebar 16,650 E. 14 Mile Rd, Fraser, MI 48,026 (USA). For more information visit www.infinityhallsidebar.com

Continue reading “Cryonics Institute’s Annual General Meeting 2022” »

This is not the first successful research on de-ageing cells. Earlier, Shinya Yamanaka, a Nobel prize-winning stem cell researcher, genetically reprogrammed the mouse skin cells and turned them into induced pluripotent stem cells, or iPSCs, back in 2006. These cells type had the potential to form any cell type in the body. Yamanaka’s method took 50 days and completely reprograms cells to the biological age of an embryo. Gill’s method only took 13 days.

In a statement, Gill said, “Our results represent a big step forward in our understanding of cell reprogramming. We have proved that cells can be rejuvenated without losing their function and that rejuvenation looks to restore some function to old cells.”