Lifeboat Foundation

The trial was only on 8 people, but it appears to have worked well across the board.

Published in GeroScience, a groundbreaking study from the renowned Conboy lab has confirmed that plasma dilution leads to systemic rejuvenation against multiple proteomic aspects of aging in human beings.

This paper takes the view that much of aging is driven by systemic molecular excess. Signaling molecules, antibodies, and toxins, which gradually accumulate out of control, cause cells to exhibit the gene expression that characterizes older cells.

Continue reading “Plasma Dilution Appears to Rejuvenate Humans” »

Foresight Existential Hope Group.
Program & apply to join: https://foresight.org/existential-hope/

In the Existential Hope-podcast (https://www.existentialhope.com), we invite scientists to speak about long-termism. Each month, we drop a podcast episode where we interview a visionary scientist to discuss the science and technology that can accelerate humanity towards desirable outcomes.

Xhope Special with Foresight Fellow Morgan Levine.

Morgan Levine is a ladder-rank Assistant Professor in the Department of Pathology at the Yale School of Medicine and a member of both the Yale Combined Program in Computational Biology and Bioinformatics, and the Yale Center for Research on Aging. Her work relies on an interdisciplinary approach, integrating theories and methods from statistical genetics, computational biology, and mathematical demography to develop biomarkers of aging for humans and animal models using high-dimensional omics data. As PI or co-Investigator on multiple NIH-, Foundation-, and University-funded projects, she has extensive experience using systems-level and machine learning approaches to track epigenetic, transcriptomic, and proteomic changes with aging and incorporate.
this information to develop measures of risk stratification for major chronic diseases, such as cancer and Alzheimer’s disease. Her work also involves development of systems-level outcome measures of aging, aimed at facilitating evaluation for geroprotective interventions.

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What does the future of aging and longevity hold? Can science hack the human lifespan? Even if we can, SHOULD we…?

People aren’t dying as early or as easily as they used to. Innovations in modern medicine, health, and hygiene helped us extend our lives by decades, but what comes next? Would you rather live to be a healthy and hearty 90 or live to be 150 but wither away for the last 60 years? We’ll talk about it in this episode of Far Out.

Continue reading “How to Stop (And Even Reverse) Aging” »

Hevolution Foundation, a non-profit organisation that provides grants and early-stage investments to incentivise research and entrepreneurship in healthspan science, and the American Federation for Aging Research (AFAR) have today announced an international research grant programme to enable early-career investigators to conduct research into healthspan-expanding therapeutics and treatments.

Longevity. Technology: Founded in the belief that every person has the right to live a longer, healthier life, Hevolution Foundation is on a mission to drive efforts to extend healthy human lifespan and understand the processes of aging. With a focus on aging as a treatable process, the Foundation aims to increase the number of aging-related treatments on the market, compress the timeline of drug development and increase accessibility to therapeutics that extend healthspan.

A non-profit organisation headquartered in Riyadh, with an annual budget of up to $1 billion, Hevolution Foundation plans to open hubs in North America and other global locations to support a cutting-edge, global ecosystem of talent to propel aging and geroscience research forward and achieve medical breakthroughs to help humanity live healthier, longer.

Immortality exists – but to get it, you need to be a jellyfish, not a god or a vampire. Moreover, only one species of cnidarian, Turritopsis dohrnii, is known to have found the secret of eternal life. Geneticists hope comparing T. dornii’s DNA with its close relative, T. rubra, will help us understand the aging process and how to evade it.

Turritopsis are warm water jellyfish half a centimeter (0.2 inches) long. At least three species of hydra have the capacity to age backwards like Benjamin Button, going from adult to juvenile stage, before eventually growing up again. However, two of these can only go from the hydra equivalent of adolescent to child; like the victim in some uncensored fairytale, sexual reproduction locks them into adulthood. T. dohrnii, on the other hand, appears able to go from its free-floating adult stage to bottom-living polyp, known as life cycle reversal (LCR), as many times as it wants.

A paper in the journal Proceedings of the National Academy of Sciences provides a comparison of T. dorhnii and T. rubra in the hope the differences will prove enlightening, throwing in a few more distantly related types of cnidarians as well.

Scientists study the immortal jellyfish to learn about its DNA reproduction, life cycle and telomeres. New research reveals its special genes.

T. dohrnii is the only species that is biologically immortal, and now scientists have peered into its DNA to find out what lets it live forever.

Scientists say medication also used after undergoing an organ transplant is capable of extending life with only brief use

COLOGNE, Germany — A drug that patients normally take during cancer therapy may have the power to increase the human lifespan, a new study reveals. Researchers in Germany say rapamycin can cause side-effects when patients take it as a lifelong anti-aging treatment. However, their new report finds even brief usage can have a dramatic impact on longevity while cutting down on side-effects.

Duangkamon Panyapatiphan/iStock.

Button was suffering from a rare ailment that made him age backward. Meanwhile, in another similar scenario, a species of jellyfish — called turritopsis dohrnii — seems to have reached immortality.