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Category: life extension – Page 177

How Long Until We Reverse the Clock? | Dr David Sinclair

https://youtube.com/watch?v=K-70S1oycR4&feature=share

1:33…“10 years”.

Dive into the fascinating world of aging research with this thought-provoking video. Join us as we explore the latest breakthroughs and scientific advancements on the quest to reverse aging. Discover the potential strategies, therapies, and technologies that hold promise for extending healthspan and pushing the boundaries of human longevity. Get ready to embark on an exciting journey towards understanding the future of aging reversal.

Credits/source: https://www.youtube.com/@peterdiamandis.

#Aging #ReverseAging #Longevity #Healthspan #AgingResearch #AntiAging #LongevityTechnologies #AgingReversal #FutureOfAging

Taking Rejuvenation to Longevity escape velocity: Aubrey De Grey [Aging & Gerontology 2023]

At 19:46 Aubrey has a chart for 150 year olds and 1,000 year olds.

6th Edition: AGING & GERONTOLOGY — Sciinov Group.
www.agingcongress.com.

Aubrey De Grey.
President & CSO, LEV Foundation, USA
Title: Taking Rejuvenation to Longevity escape velocity.

Sciinov Group is a specialized international events organizer, and provider of customized data intelligence databases, trends and insights that solve information challenges and caters organizations needs.

Sciinov Conferences mission is to benefit attendees by networking their peers, often potential clients and learn from the high quality of information delivered by the expert speakers.

Continue reading “Taking Rejuvenation to Longevity escape velocity: Aubrey De Grey [Aging & Gerontology 2023]” | >

How Finland managed to virtually end homelessness

I believe that homelessness is often seen in America or other parts of the world as bad but with Finland they have found a housing first approach which has stopped nearly all homelessness there. I believe also regenerative medicine and lots of transhumanistic approaches to medicine would help end their aging and even repair their body if needed. Also if we research the brain we can finally discover and repair genes throughout the body essentially bringing them back near perfect and beyond. Along with ethical approaches towards a more cultural relativistic approach to all humans could show everyone how to coexist. It is still a problem of aging though which is still curable and in extreme cases will be eventually solved in the future. I think with a more comprehensive understanding of all transhumansistic medicine it would be possible to save all lives so no one is left behind.

OK, so the Finns are more generous and just shell out a lot more to help the homeless, right? Actually not. The Finns are simply smarter.

Instead of abandoning the homeless, they housed them. And that led to an insight: people tend to function better when they’re not living on the street or under a bridge. Who would have guessed?

It turns out that, given a place to live, Finland’s homeless were better able to deal with addictions and other problems, not to mention handling job applications. So, more than a decade after the launch of the “Housing First” policy, 80 per cent of Finland’s homeless are doing well, still living in the housing they’d been provided with — but now paying the rent on their own.

Breast cancer by age: Study reveals early mutations that predict patient outcomes

A study led by researchers at Sanford Burnham Prebys has found that in young women, certain genetic mutations are associated with treatment-resistant breast cancer. These mutations are not linked to treatment-resistant breast cancer in older women. The findings, published in the journal Science Advances, could help improve precision medicine and suggest a brand-new way of classifying breast cancer.

“It’s well established that as you get older, you’re more likely to develop cancer. But we’re finding that this may not be true for all cancers depending on a person’s genetic makeup,” says senior author Svasti Haricharan, Ph.D., an assistant professor at Sanford Burnham Prebys. “There may be completely different mechanisms driving cancer in younger and older people, which requires adjusting our view of aging and cancer.”

The research primarily focused on ER+/HER2-, which is one of the most common forms of the disease. It is usually treated with hormonal therapies, but for some patients, these treatments don’t work. About 20% of tumors resist treatment from the very beginning, and up to 40% develop resistance over time.

Rapamycin — All You Need To Know & Get Started | Dr Ross Pelton Ep1

And he mentions Internatioan Aging Systems where you can legally order Rapamycin but I would have to know what experience people have had with them and their product first myself.

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In this video Pelton talks all about rapamycin, its history, how it works, dosage and timing. He also talks about where you can get rapamycin online.

Ross Pelton is a pharmacist, nutritionist, author, and health educator. He is the founder of The Natural Pharmacist, a website and online resource that provides information about natural health and nutrition. Pelton is also the author of several books, including The Drug-Induced Nutrient Depletion Handbook, The Nutritional Cost of Drugs, and Alternatives in Cancer Therapy. He is a recognized expert on drug-induced nutrient depletions and has been featured in publications such as The New York Times, The Wall Street Journal, and Time magazine.

00:00 History of rapamycin.
03:00 Rapamycin for life extension.
05:50 mTOR & autophagy.
14:30 mTOR research.
16:00 Who can & can’t take rapamycin.
22:40 Rapamycin research & info.
24:50 Metrics to watch.
26:55 How to take rapamycin.
29:09 Getting started with rapamycin.

Dr Ross Pelton’s links.

Continue reading “Rapamycin — All You Need To Know & Get Started | Dr Ross Pelton Ep1” | >

Oxygen restriction helps fast-aging lab mice live longer

For the first time, researchers have shown that reduced oxygen intake, or “oxygen restriction,” is associated with longer lifespan in lab mice, highlighting its anti-aging potential. Robert Rogers of Massachusetts General Hospital in Boston, US, and colleagues present these findings in a study published May 23rd in the open access journal PLOS Biology.

Research efforts to extend healthy lifespan have identified a number of chemical compounds and other interventions that show promising effects in mammalian lab animals— for instance, the drug metformin or . Oxygen restriction has also been linked to longer lifespan in yeast, nematodes, and fruit flies. However, its effects in mammals have been unknown.

To explore the anti-aging potential of oxygen restriction in mammals, Rogers and colleagues conducted lab experiments with mice bred to age more quickly than other mice while showing classic signs of mammalian aging throughout their bodies. The researchers compared the lifespans of mice living at normal atmospheric oxygen levels (about 21%) to the lifespans of mice that, at 4 weeks of age, had been moved to a living environment with a lower proportion of oxygen (11%—similar to that experienced at an altitude of 5,000 meters).

Rapamycin is the gold standard for longevity interventions

It sucks that the primary reason this has not gone forward is because it is off patent.

This video is reproduced from a presentation I gave to the Euro-Geroscience Task Force “Challenges in Developing Geroscience Drug Trials” held March 23, 2022 in Toulouse, France. It gives an introduction to the state of research on rapamycin as a potential longevity and healthspan drug and some of the challenges and opportunities for clinical development.

Andrew Steele: Curing aging is a question of investment, not time

The 2023 edition of the exclusive Longevity Investors Conference is fast approaching, bringing together investors, companies and researchers in Gstaad, Switzerland in September. One of the speakers at this year’s conference is scientist, writer and presenter Dr Andrew Steele, the author of the best-selling book Ageless: The new science of getting older without getting old. When it comes to his views on longevity, Steele sits firmly in the camp that aging, like cancer, is something that humanity should be focused on curing.

Longevity. Technology: Last year, Steele told us he was “absolutely convinced” curing aging is possible, but that significant questions remain around how quickly we can get there. As he prepares to speak to more than 100 investors at LIC, we caught up with Steele to see how his views on longevity have evolved, and what he would say to those considering investing in the field.

First and foremost, Steele, who recently published a new, free chapter of Ageless on the moral, ethical and social consequences of treating aging, believes that longevity represents a huge “human opportunity” for investors.

The Millennium Project receives the 2023’s Award for Excellence in Innovation

The winners of the Non-Profit Organisation Awards 2023 by Acquisition International have just been announced and The Millennium Project has been awarded for Excellence in Innovation – USA!

The Non-Profit Organisation Awards aim to reward Non-profit organizations that globaly that play a monumental role in solving some of our biggest global challenges. The awards reward commitment, innovation, and determination of the best NPOs from across the world by selecting the most innovative, creative and compassionate NPOs, and provide a platform for NPOs to demonstrate that they are a true leader within the non-profit sphere.

The approach for nominations includes gathering and evaluating the nominees, research and judging on various criteria, including client dedication, innovation, business growth, longevity, online reputation, client feedback and business performance, and announcement of the winners.

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