Lifeboat Foundation: Safeguarding Humanity
Toggle light / dark theme

Blog

Category: life extension – Page 172

University of Missouri researchers made the discovery while using bioluminescent imaging technology to study how nicotinamide riboside supplements work inside the body.

Commercial dietary supplements like nicotinamide riboside (NR), a form of vitamin B3, were linked to benefits related to cardiovascular, metabolic, and neurological health in previous studies. However, new research from the University of Missouri (MU) has found NR could actually increase the risk of serious disease, including developing cancer.

Supplements containing nicotinamide riboside are often marketed as NAD+ boosters claimed benefits including increased energy, anti-aging/longevity/healthy aging, improved cellular energy metabolism and repair, increased vitality, and improved heart health.

Read more | >

Join us on Patreon!
https://www.patreon.com/MichaelLustgartenPhD

TruDiagnostic Discount Link (Epigenetic Testing)
CONQUERAGING!
https://bit.ly/3Rken0n.

Bristle Discount Link (Oral Microbiome Quantification):
ConquerAging15
https://www.bmq30trk.com/4FL3LK/GTSC3/

Quantify Discount Link (At-Home Blood Testing)

Continue reading “Longitudinal Biomarker Optimization: A Road To Maximize Health And Longevity?” | >

Longevity is not yet considered an official medical term, and aging is not officially considered a disease but a natural occurrence in every living thing.

However, some biologists, researchers and practicing doctors believe this approach should change, and they are striving to discover the mechanisms of aging in humans. In doing so, they are creating age clocks by defining biomarkers for measuring biological age, exploring the best lifestyle habits and natural supplements, and inventing new drugs that could stop us from getting older.

Longevity has been on the radar of crypto leaders for some time already, which is not a surprise given that the industry promises to improve humankind through innovation. Indeed, one prominent event in the longevity industry, the Longevity Investors Conference, is organized by Marc P. Bernegger and Tobias Reichmuth, who were previously involved with the Crypto Finance Group.

Read more | >

Ever wonder why some 90-year olds don’t seem to slow down and seem. to retain the mental and physical capacity of someone half their age?
Do they have good genes? Or is there a way that all of us can get older without getting old?

That’s what Dr. Nir Barzilai, founder of the Institute for Aging Research at the Albert Einstein College of Medicine, set out to answer in his book, Age Later.

Dr. Nir joined us for a live Q + A discussion on Zoom.
Whether you’ve read Age Later or not, you won’t want to miss this. Because by the end of the discussion, you’ll know how to turn back the clock on aging.

Listen to the Longevity by Design podcast episode with Dr. Nir’s on genetics and lifestyle factors of centenarians here: https://hubs.li/Q01rqsV-0

Continue reading “A discussion with Dr. Nir Barzaili on Age Later” | >

Summary: The epigenetic clocks of those who indulged in unhealthy behaviors as teens were 1.7 to 3.3 years older than individuals who reported more healthy lifestyles as teens.

Source: eLife.

Biological aging results from damage to cells and tissues in the body that accumulates over time. The results of the study could lead to new ways of identifying young people at risk of developing unhealthy habits that are associated with accelerated biological aging and suggest interventions to prevent poor health outcomes later on.

Read more | >

Scientists at the University of Pittsburgh School of Medicine have discovered the missing puzzle piece in the mystery of how melanoma tumors control their mortality.

In a paper published in Science this week, Jonathan Alder, Ph.D. and his team describe how they discovered the perfect combination of genetic alterations that tumors use to promote explosive growth and prevent their own demise, a development that could change the way oncologists understand and treat melanoma.

“We did something that was, in essence, obvious based on previous basic research and connected back to something that is happening in patients,” said Alder, assistant professor in the Division of Pulmonary, Allergy and Critical Care Medicine at Pitt’s School of Medicine.

Read more | >

We use cookies on our website. Some of them are essential, while others help us to improve this website and your experience. If you are under 16 and wish to give consent to optional services, you must ask your legal guardians for permission. We use cookies and other technologies on our website. Some of them are essential, while others help us to improve this website and your experience. Personal data may be processed (e.g. IP addresses), for example for personalized ads and content or ad and content measurement. You can find more information about the use of your data in our privacy policy. You can revoke or adjust your selection at any time under Settings.

Read more | >

Today, Deep Longevity, a company will launch its new software as a service (SaaS) antiaging platform, SenoClock. The culmination of years of biogerontological research, SenoClock will host all of Deep Longevity’s patented aging clocks that may be used in clinical practice and other healthcare-adjacent industries.

Aging clocks available on the platform will allow its users to receive comprehensive and actionable pace of aging reports based on various data types, such as blood tests, psychological surveys, gut flora composition and more.

Longevity. Technology: Hospitals and clinics are mostly reactive when it comes to treatment, a practice that is partly due to infrastructure and partly due to human nature. However, as we discussed in our interview with Sir John Bell earlier this week, prevention must be the new paradigm and its one that better serves individuals, healthcare systems and populations as a whole. Deep Longevity’s new product SenoClock unlocks a preventive, longevity-focused mode of healthcare; a new SaaS platform, SenoClock offers physicians a single portal in which to track the aging rate of their patients, enabling them to generate personalised health plans.

Read more | >

A team of researchers at Umeå University has discovered that an enzyme in human cells has probably evolved from an ancient single-celled organism. The enzyme’s unique properties mean that it could be used as a building block in the design of new enzymes, for example in processing wood raw materials. The discoveries are presented in Science Advances.

Life on Earth is divided into three groups of organisms: bacteria, archaea and eukaryotes, with humans belonging to the last group, the eukaryotes. One theory is that we evolved from archaea, which in turn may have evolved from bacteria.

Now, a team of researchers from the Department of Chemistry at Umeå University has discovered clear traces of an archaea (odinarchaeota) in an found in the nucleus of . The human enzyme is called AK6 and has a variety of functions, such as energy metabolism, genome stabilization and programmed cell death.

Read more | >

In a study recently published in the journal Nature Biomedical Engineering, researchers from Kanazawa University use a method called “lasso-grafting” to design therapeutics with enhanced longevity and brain penetration.

Cell growth and repair are stimulated by biomolecules known as cytokines and growth factors. Unfortunately, delivering adequate concentrations of these molecules to the for treating neurological conditions like Alzheimer’s disease is challenging as they are either cleared out of the blood very quickly or do not penetrate effectively.

A research team led by Kunio Matsumoto and Katsuya Sakai at Kanazawa University in collaboration with Junichi Takagi, Osaka University and Hiroaki Suga, the University of Tokyo has now used a technique called “lasso-grafting” to design molecules that replicate growth factors with longer retention in the body and brain penetration.

Read more | >