In an interview with GQ, 54-year-old David Sinclair says his lifestyle changes got him back to his “20-year-old brain.”
Category: life extension – Page 161
Microbial Composition May Affect Lifespan
New research published in Scientific Reports suggests that microbes in the human gut and mouth can impact how long people live [1].
Bacteria and other microbes are often associated with diseases, but disease-causing microbes are only a minority. The majority of microbes are harmless or beneficial to humans, and we have millions of them living inside and outside us. Researchers refer to this community as the microbiota.
In previous research, scientists had noticed an association between microbiota and longevity [2]. However, the association between two things does not necessarily mean that one is causing the other. Therefore, in this new paper, researchers explored potential causal relationships between gut and mouth microbes’ composition and longevity in order to determine what compositions of microbiota result in increases or decreases in lifespan.
Grand Opening of our Research Center Expansion
On January 23, 2023, we celebrated the expansion of the SENS Research Foundation’s Research Center, more than doubling its capacity.
California Dignitaries Alison Hicks, Mayor of Mountain View, Peter Katz, President of the Mountain View Chamber of Commerce, Marc Berman, California State Assemblymember, and Saul Miranda, District Representative, were present to officiate the ribbon-cutting ceremony.
SENS Research Foundation was awarded a Certificate of Recognition by Senator Josh Becker, California State Senate.
Video by Vecc Schiafino.
Dr. Aubrey de Grey, Ph.D. — President & Chief Science Officer, Longevity Escape Velocity Foundation
Accelerating Effective Treatments To Prevent And Reverse Human Age-Related Disease — Dr. Aubrey de Grey, Ph.D. — President & Chief Science Officer, Longevity Escape Velocity Foundation (LEVF)
Dr. Aubrey de Grey, Ph.D., is President & Chief Science Officer of the Longevity Escape Velocity (LEV) Foundation (https://www.levf.org/), an organization focused on proactively identifying and addressing the most challenging obstacles on the path to the widespread availability of genuinely effective treatments to prevent and reverse human age-related disease.
Dr. de Grey is internationally recognized as a visionary biomedical gerontologist who devised the Strategies for Engineered Negligible Senescence: a comprehensive set of methods to rejuvenate the human body, thereby preventing age-related ill health and mortality. He has co-founded multiple non-profit organizations – including Methuselah Foundation, SENS Research Foundation, and now LEV Foundation – to specifically enable and accelerate its development and clinical translation.
Dr. de Grey received his BA in Computer Science and Ph.D. in Biology from the University of Cambridge in 1985 and 2000, respectively. He is the author of The Mitochondrial Free Radical Theory of Aging (1999), Ending Aging (2007), and a large number of academic papers.
Dr. de Grey is a Fellow of both the Gerontological Society of America and the American Aging Association, and sits on the advisory boards of numerous scientific journals and research organizations. He is a prolific speaker who regularly presents at conferences and events world-wide.
How Long Until We Reverse the Clock? | Dr David Sinclair
https://youtube.com/watch?v=K-70S1oycR4&feature=share
1:33…“10 years”.
Dive into the fascinating world of aging research with this thought-provoking video. Join us as we explore the latest breakthroughs and scientific advancements on the quest to reverse aging. Discover the potential strategies, therapies, and technologies that hold promise for extending healthspan and pushing the boundaries of human longevity. Get ready to embark on an exciting journey towards understanding the future of aging reversal.
Credits/source: https://www.youtube.com/@peterdiamandis.
#Aging #ReverseAging #Longevity #Healthspan #AgingResearch #AntiAging #LongevityTechnologies #AgingReversal #FutureOfAging
Taking Rejuvenation to Longevity escape velocity: Aubrey De Grey [Aging & Gerontology 2023]
At 19:46 Aubrey has a chart for 150 year olds and 1,000 year olds.
6th Edition: AGING & GERONTOLOGY — Sciinov Group.
www.agingcongress.com.
Aubrey De Grey.
President & CSO, LEV Foundation, USA
Title: Taking Rejuvenation to Longevity escape velocity.
Sciinov Group is a specialized international events organizer, and provider of customized data intelligence databases, trends and insights that solve information challenges and caters organizations needs.
Sciinov Conferences mission is to benefit attendees by networking their peers, often potential clients and learn from the high quality of information delivered by the expert speakers.
How Finland managed to virtually end homelessness
I believe that homelessness is often seen in America or other parts of the world as bad but with Finland they have found a housing first approach which has stopped nearly all homelessness there. I believe also regenerative medicine and lots of transhumanistic approaches to medicine would help end their aging and even repair their body if needed. Also if we research the brain we can finally discover and repair genes throughout the body essentially bringing them back near perfect and beyond. Along with ethical approaches towards a more cultural relativistic approach to all humans could show everyone how to coexist. It is still a problem of aging though which is still curable and in extreme cases will be eventually solved in the future. I think with a more comprehensive understanding of all transhumansistic medicine it would be possible to save all lives so no one is left behind.
OK, so the Finns are more generous and just shell out a lot more to help the homeless, right? Actually not. The Finns are simply smarter.
Instead of abandoning the homeless, they housed them. And that led to an insight: people tend to function better when they’re not living on the street or under a bridge. Who would have guessed?
It turns out that, given a place to live, Finland’s homeless were better able to deal with addictions and other problems, not to mention handling job applications. So, more than a decade after the launch of the “Housing First” policy, 80 per cent of Finland’s homeless are doing well, still living in the housing they’d been provided with — but now paying the rent on their own.
Breast cancer by age: Study reveals early mutations that predict patient outcomes
A study led by researchers at Sanford Burnham Prebys has found that in young women, certain genetic mutations are associated with treatment-resistant breast cancer. These mutations are not linked to treatment-resistant breast cancer in older women. The findings, published in the journal Science Advances, could help improve precision medicine and suggest a brand-new way of classifying breast cancer.
“It’s well established that as you get older, you’re more likely to develop cancer. But we’re finding that this may not be true for all cancers depending on a person’s genetic makeup,” says senior author Svasti Haricharan, Ph.D., an assistant professor at Sanford Burnham Prebys. “There may be completely different mechanisms driving cancer in younger and older people, which requires adjusting our view of aging and cancer.”
The research primarily focused on ER+/HER2-breast cancer, which is one of the most common forms of the disease. It is usually treated with hormonal therapies, but for some patients, these treatments don’t work. About 20% of tumors resist treatment from the very beginning, and up to 40% develop resistance over time.
Rapamycin — All You Need To Know & Get Started | Dr Ross Pelton Ep1
And he mentions Internatioan Aging Systems where you can legally order Rapamycin but I would have to know what experience people have had with them and their product first myself.
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In this video Pelton talks all about rapamycin, its history, how it works, dosage and timing. He also talks about where you can get rapamycin online.
Ross Pelton is a pharmacist, nutritionist, author, and health educator. He is the founder of The Natural Pharmacist, a website and online resource that provides information about natural health and nutrition. Pelton is also the author of several books, including The Drug-Induced Nutrient Depletion Handbook, The Nutritional Cost of Drugs, and Alternatives in Cancer Therapy. He is a recognized expert on drug-induced nutrient depletions and has been featured in publications such as The New York Times, The Wall Street Journal, and Time magazine.
00:00 History of rapamycin.
03:00 Rapamycin for life extension.
05:50 mTOR & autophagy.
14:30 mTOR research.
16:00 Who can & can’t take rapamycin.
22:40 Rapamycin research & info.
24:50 Metrics to watch.
26:55 How to take rapamycin.
29:09 Getting started with rapamycin.
Dr Ross Pelton’s links.