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Category: life extension – Page 16
Attempting To Slow Aging By Optimizing Biomarkers
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Aging Can Spread Through Your Body Via a Single Protein, Study Finds
Take note of the name: ReHMGB1. A new study pinpoints this protein as being able to spread the wear and tear that comes with time as it quietly travels through the bloodstream. This adds significantly to our understanding of aging.
Short for reduced high mobility group box 1, ReHMGB1 triggers senescence in cells, permanently disabling them. It doesn’t just do this locally; it can send damaging signals throughout the body, particularly in response to injuries or disease.
“An important question in aging research is why senescent cells increase with age,” write the study authors, led by researchers from the Korea University College of Medicine.
The first 25 years of SuperAger research show cognitive decline is not an inevitable part of aging
For 25 years, scientists at Northwestern Medicine have been studying individuals aged 80 and older—dubbed “SuperAgers”—to better understand what makes them tick.
These unique individuals, who show outstanding memory performance at a level consistent with individuals who are at least three decades younger, challenge the long-held belief that cognitive decline is an inevitable part of aging.
Over the quarter-century of research, the scientists have seen some notable lifestyle and personality differences between SuperAgers and those aging typically—such as being social and gregarious—but “it’s really what we’ve found in their brains that’s been so earth-shattering for us,” said Dr. Sandra Weintraub, a professor of psychiatry and behavioral sciences and neurology at Northwestern University Feinberg School of Medicine.
