No questions concerning plasma dilution or E5, but a good interview with chapters.
Professor Matt Kaeberlein discusses the Dog Aging Project, longevity, Rapamycin, mTOR, and if we can ‘solve aging’
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Today we have the impression that our planet is a stable place, in exception of some natural disasters. But there was times earth was not a live-friendly place. A important condition for life is the presence of liquid water (maybe not everywhere). Land was inhabitated till the Ordovizium because of air Oxygen poverty.
Many Factors are changing the state of our planet. For first the sun which is increasing their radiation by ageing. This is evident because it shifts the inner bounder of the habitable zone away from sun. Another Problem is the ageing of earth and the decreasing of geological activities. This will reduce the exhaust of greenhouse gasses and so the outer border of habitable zone will shrink. Maybe after 500 Million years life on earth is no more possible, but just Pangea Ultimo will be a very hostile, deserted World. Later Water will evaporate, combinated with volcanic gases Earth will get a very dense athmosphere very Venus-like. This state will Keep for billions of year — a very sad end for our planet before Sun, after the collapse of hydrogen burning and a instable phase will finally inflate to a red giant. It’s not sure if earth will be absorbed but otherwise it would be a devastated, lonely planet travelling through space… Have you ideas for another Video — write it in the coments — best ideas will be realized… I also make gaming-Videos about Amazing-Frog and Minecraft, my Server https://minewind.com …
Dr. Campisi has been at the forefront of studying cellular senescence for decades, revealing the mysteries of these not-exactly-dead cells and their role in many diseases of aging. In this episode, she joins her colleague Gordon to discuss the characteristics and function of senescent cells, as well as promising interventions on the horizon. Judy also describes how to get lucky in science by being prepared to see the unexpected.
DISCLOSURE: Longevity. Technology (a brand of First Longevity Limited) has been contracted by the company featured in this article to support its current funding round. Qualifying investors can find out more via the Longevity. Technology investment portal.
MedTech start-up Occuity has received a £343,000 Innovate UK Biomedical Catalyst (BMC) Award to fund the next stage of the development of its innovative AGE reader: an optical medical device that will enable non-invasive screening of diabetes in non-clinical settings such as opticians and pharmacies.
Biomedical Catalyst is the flagship Innovate UK grant funding competition for supporting UK health & life sciences SMEs. It supports the development of innovative solutions to health and healthcare challenges by providing financial support to accelerate the route to commercialisation.
Magnetic fields are all around us. They exist whenever there is electric current and have been used in various aspects of medicine for decades. Today, magnetic fields are used in applications including magnetic resonance imaging (MRI), bone fracture repair, wound healing and pain reduction.
Taking things a step further, US startup EMulate Therapeutics has developed a unique magnetic field technology that has been shown to replicate the effect of drugs in humans and animal models – all without the presence of chemicals. Having spun-out companies in cancer, pain management and beyond, the company is seeking partners for longevity applications of its technology.
Longevity. Technology: The concept behind EMulate’s approach is mind-boggling. The company “records” the electromagnetic signature of specific molecules and is then able to use those recordings to effect changes in cellular behaviour, without using chemicals. In its most advanced programme, EMulate’s technology has completed feasibility clinical trials for adults and children with terminal brain cancer, using a recording derived from chemotherapy drug paclitaxel. We caught up with EMulate’s CEO Chris Rivera to find out more.
Neuralink’s invasive brain implant vs phantom neuro’s minimally invasive muscle implant. Deep dive on brain computer interfaces, Phantom Neuro, and the future of repairing missing functions.
Connor glass.
Phantom is creating a human-machine interfacing system for lifelike control of technology. We are currently hiring skilled and forward-thinking electrical, mechanical, UI, AR/VR, and Ai/ML engineers. Looking to get in touch with us? Send us an email at [email protected].
Evidence-Based And Actionable Health, Wellness And Longevity Solutions — Dr. Renee DeHaan, Ph.D. — VP, Science & AI, InsideTracker
Dr. Renée Deehan, Ph.D. is the VP of Science & Artificial Intelligence at InsideTracker (https://www.insidetracker.com/), and leads a science team that builds and mines the world’s largest data set of blood, DNA, fitness tracking and phenotypic data from healthy people, creating evidence-based solutions that are simple, clear, and actionable.
Metformin has been proposed as an “anti-aging drug,” and a major clinical trial is about to get underway to test the idea.
New research from the University of California, Irvine, suggests aging is an important component of retinal ganglion cell death in glaucoma, and that novel pathways can be targeted when designing new treatments for glaucoma patients.
The study was published today in Aging Cell. Along with her colleagues, Dorota Skowronska‐Krawczyk, Ph.D., assistant professor in the Departments of Physiology & Biophysics and Ophthalmology and the faculty of the Center for Translational Vision Research at the UCI School of Medicine, describes the transcriptional and epigenetic changes happening in aging retina.
The team shows how stress, such as intraocular pressure (IOP) elevation in the eye, causes retinal tissue to undergo epigenetic and transcriptional changes similar to natural aging. And, how in young retinal tissue, repetitive stress induces features of accelerated aging including the accelerated epigenetic age.
Fasting database:
Recreates the immune system;…Prolonged fasting forces the body to use stores of glucose, fat and ketones, but it also breaks down a significant portion of white blood cells. Longo likens the effect to lightening a plane of excess cargo. During each cycle of fasting, this depletion of white blood cells induces changes that trigger stem cell-based regeneration of new immune system cells. In particular, prolonged fasting reduced the enzyme PKA, an effect previously discovered by the Longo team to extend longevity in simple organisms and which has been linked in other research to the regulation of stem cell self-renewal and pluripotency — that is, the potential for one cell to develop into many different cell types. Prolonged fasting also lowered levels of IGF-1, a growth-factor hormone that Longo and others have linked to aging, tumor progression and cancer risk.
Recreates the immune system (page loads slow)
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