https://www.youtube.com/watch?v=lXTiqZGtnvc&list=PLr-AM3…mp;index=2
Today there might not be a cure to save your life. What if the cure were available tomorrow? Biostasis (cryonics) is a possibility for keeping you around long enough for the cure.
One of the hallmarks of aging, cellular senescence is what happens when aging cells do not die in the usual way (a process known as apoptosis) and start to accumulate in our bodies. The accumulation of these “senescent” cells is implicated in diseases including dementias, atherosclerosis, cancers, diabetes and arthritis. But senescence is not just part of the aging process – it tends to occur in individuals who develop frailty and multiple illnesses, and this can occur at any point during life.
In 2015, a team of researchers at the Mayo Clinic, led by Dr James L Kirkland, published a seminal paper in Aging Cell that introduced a new class of drugs called senolytics. Based on the idea that removing senescent cells may enhance human healthspan, these drugs were identified based on their ability to selectively target and eliminate those cells.
Longevity. Technology: Since the discovery of the first senolytics, hundreds of others have since been identified or created, and senotherapeutics is now one of the hottest areas in longevity, with a host of clinical trials under way and companies pursuing senolytic therapies for a range of age-related conditions. But what does the man who started it all think about the therapeutic field he helped create? In the first of two articles, we bring you Dr Kirkland’s unique perspective on the world of senolytics.
This video is the 1st of a series of “What is Aging” webinars that aims to unravel what aging is, how we age, why we age, and how to reverse it.
We welcome Jason C. Mercurio, MFE, Dr. Jose Cordeiro, and Dr. Ian Hale to discuss the topic.
“The idea was to build a society like we have for all the other disciplines in medicine,” says Evelyne Bischof, a professor of medicine at Shanghai University of Medicine and Health Sciences and the inaugural vice president of the society. She has previously spearheaded educational efforts with Zhavoronkov and others, co-developing a formal course on longevity medicine for doctors. At the ARDD meeting, Bischof announced their course had just received continuing medical education (CME) accreditation from the American Medical Association.
“Longevity medicine is crystallizing as a discipline,” says Andrea Maier, an internal medicine specialist and geriatrician at National University of Singapore who is serving as the society’s inaugural president. One thing that’s not yet clear, several experts told me, is whether longevity will come to be established as a sub-discipline of geriatrics or internal medicine or whether it will become a separate medical specialty unto itself.
“Whichever way it goes,” Maier says, “it’s happening.”
Building A Clinically Credible Platform For Longevity Medicine — Prof. Dr. Andrea Maier MD, PhD, National University of Singapore, Centre for Healthy Longevity.
Professor Dr. Andrea B. Maier, MD, Ph.D., is the Oon Chiew Seng Professor in Medicine, Healthy Ageing and Dementia Research, and Co-Director of the Centre for Healthy Longevity, at the National University Of Singapore (https://discovery.nus.edu.sg/19564-andrea-britta-maier).
Just a matter of time for people.
Anti-Aging interview with David Sinclair by Mr. Myllet.
Continue reading “The Aging Process Is Unstoppable, Or Is It…?” »
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Michael Levin is a biologist at Tufts University working on novel ways to understand and control complex pattern formation in biological systems. Please support this podcast by checking out our sponsors:
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EPISODE LINKS:
Michael’s Twitter: https://twitter.com/drmichaellevin.
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Michael’s Papers:
Biological Robots: https://arxiv.org/abs/2207.00880
Synthetic Organisms: https://tandfonline.com/doi/full/10.1080/19420889.2021.2005863
Limb Regeneration: https://science.org/doi/10.1126/sciadv.abj2164
Excerpt from an episode of Longevity by Design, hosted by Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, who were joined by Dr. George Church, Professor of Genetics at Harvard Medical School.
To watch the entire conversation clic here: https://youtu.be/6XnXeVS1m2U
Foresight Biotech & Health Extension Meeting sponsored by 100 Plus Capital.
Program & apply to join: https://foresight.org/biotech-health-extension-program/
Jennifer Garrison, Buck Institute.
Reframing Health and Aging through the Lens of Reproduct.
