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Category: life extension – Page 112
Keeping a cell’s nucleolus compact may be key to fighting aging
The secret to cellular youth may depend on keeping the nucleolus—a condensed structure inside the nucleus of a cell—small, according to Weill Cornell Medicine investigators. The findings were elucidated in yeast, a model organism famous for making bread and beer and yet surprisingly similar to humans on the cellular level.
The study, published Nov. 25 in Nature Aging, may lead to new longevity treatments that could extend human lifespan. It also establishes a mortality timer that reveals how long a cell has left before it dies.
As people get older, they are more likely to develop health conditions, such as cancer, cardiovascular disease and neurodegenerative diseases.
Ed Boyden — The Future of Humanity | Xapiens Symposium
This is the first symposium of Xapiens at MIT — “The Future of Homo Sapiens”
The future of our species will be majorly influenced by the technical advancements and ethical paradigm shifts over the next several decades. Artificial intelligence, neural enhancement, gene editing, solutions for aging and interplanetary travel, and other emerging technologies are bringing sci-fi’s greatest ideas to reality.
Sponsored by the MIT media lab and the MIT mcgovern institute of brain research.
Full Agenda:
- Openings remarks from Joe Paradiso — https://youtu.be/9bG40ySgE8I
A.W Dreyfoos Professor and Associate Academic Head of Media Arts and Sciences at MIT Director of the Responsive Environments Group.
- Pattie Maes — https://youtu.be/b-16PW9RvJc.
How tiny droplets can deform ice: Findings show potential for cryopreservation and food engineering
When water freezes slowly, the location where water turns into ice—known as the freezing front—forms a straight line. Researchers from the University of Twente showed how droplets that interact with such a freezing front cause surprising deformations of this front. These new insights were published in Physical Review Letters and show potential for applications in cryopreservation and food engineering techniques.
When water freezes, it is often thought of as a predictable, solid block forming layer by layer. But what happens if the progressing freezing front encounters tiny particles or droplets? Researchers from the University of Twente have explored this question, discovering that droplets can cause surprising deformations in the way ice forms.
Early adult binge drinking has lasting impact on aging brain in mice
In a new work, a team from the University of Pennsylvania tracked the impact of alcohol consumption from the age of 20 on brain health and came to disappointing conclusions.
UNIVERSITY PARK, Pa. — Binge drinking in early adults can lead to long-lasting and potentially permanent dysregulation in the brain, according to a new study in mice, led by researchers at Penn State. They found that neurons, cells that transmit information in the brain via electrical and chemical signals, showed changes following binge drinking were similar in many ways to those seen with cognitive decline.
These findings, published in the journal Neurobiology of Aging, reveal that binge drinking early in life may have lasting impacts that are predictive of future health issues, like Alzheimer’s disease and related dementias, the researchers said. The work could inform the development of therapeutics to help combat these changes — particularly in aging populations who may have given up alcohol decades earlier, according to Nikki Crowley, director of the Penn State Neuroscience Institute at University Park, Huck Early Career Chair in Neurobiology and Neural Engineering, assistant professor of biology in the Eberly College of Science, and the leader of the research team.
“We know from previous studies that there are immediate effects of binge drinking on the brain, but we didn’t have any sense of if these changes were long-lasting, or reversible over time,” said Crowley, who is also an assistant professor of biomedical engineering and of pharmacology. “We were interested in understanding if binge drinking during early adulthood may have lasting consequences that are not revealed until later in life — even if drinking had stopped for a very long period of time. This allows us to consider the effects of alcohol on an individual’s holistic health, in terms of their entire life history.”
Bright Nights, Dark Days, And Low Greenspace Exposure Are Associated With Poor Health
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RNA editing is the next frontier in gene therapy—here’s what you need to know
The United States Food and Drug Administration has just approved the first-ever clinical trial that uses CRISPR-Cas13 RNA editing. Its aim is to treat an eye disease called wet age-related macular degeneration that causes vision loss in millions of older people worldwide.
This trial marks a new frontier in gene therapy —the process of treating or curing medical conditions by changing a person’s genes.
What makes it special is the fact the therapy targets RNA, instead of DNA. So, what does that mean, and why should we be excited?
Why We Die: The New Science of Aging and the Quest for Immortality (Audio Summary)
Please consider adding this book to your collection. The more places wisdom is preserved, the better!
https://www.amazon.com/Why-We-Die-Sci?tag=lifeboatfound-20…
Death — the ultimate enigma that has haunted humanity since the dawn of consciousness. In \.