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Archive for the ‘innovation’ category: Page 131

Jul 22, 2020

P2.180 TMR5 (ZedupexTM) as a Management Therapy For Herpes Infections: Results of Preclinical Evaluations

Posted by in categories: biotech/medical, innovation

Did you know there was a natural treatment for herpes “that has no treatment”. People have been treating disease for centuries. Just because something is not approved does not mean it does not work, it only means it is not approved. Even corruption can stall the approval process.


TMR5 (ZedupexTM) is a product of a Kenyan medicinal plant, prepared as a lyophilized extract and a cream. The products have been evaluated for preclinical safety and efficacy in suitable in vitro and in vivo systems of herpes infections. Herpes is a viral infection affecting over 60% of the sub-Saharan Africa young adult population. It is caused by two similar viruses, HSV-1 and HSV-2 which share 50% gene sequence homology. The infection in a major cause of genital ulcer disease, associated with increased risks of HIV acquisition and transmission. The aim is to develop TMR5 as an alternative anti-herpes agent, this being necessitated by increased resistance to available drugs and the cost of the drug of choice, acyclovir, in the region. Using the trypan blue exclusion test, plaque inhibition and viral yield reduction assays for assessment of cytotoxicity (CC50) and efficacy (EC50), and Mice and guinea pig cutaneous and genital HSV infection models respectively following oral and topical treatments, TMR5 exhibited no cytotoxicity in mammalian cell lines with a wide therapeutic index (CC50 ≥ 58.5 ± 4.6µg/ml). An EC50 of ≤ 14.7 ± 3.7µg/ml for both wild type and resistant strains of HSV was realised in plaque and viral yield assays. Oral (250 mg/kg) and topical (10% cream) administrations exhibited significant delay in onset of infections, hindered progression of infection to lethal forms with increased mean survival times and low mortality in both mice and guinea pig models. No acute toxicity has been realised at the therapeutic concentrations. TMR5 has demonstrated a high potential as an anti-herpes agent and arrangements are presently underway to evaluate its efficacy and safety in human clinical trials. A pilot production scheme supported by the National Commission for Science, Technology and Innovation (NCSTI) of Kenya has been undertaken as means of developing TMR5 as an alternative management therapy for herpes infections.

Jul 21, 2020

Machines can learn unsupervised ‘at speed of light’ after AI breakthrough, scientists say

Posted by in categories: innovation, robotics/AI

Performance of photon-based neural network processor is 100-times higher than electrical processor.

Jul 14, 2020

NASA’S Ingenuity Mars Helicopter: The First Aircraft on Mars

Posted by in categories: innovation, space

When NASA’s Perseverance Mars Rover launches to the Red Planet, an innovative experiment will ride along: the Ingenuity Mars Helicopter — the first aircraft to attempt controlled flight on another planet.

Get up to speed with these key facts about its plans: https://www.nasa.gov/feature/jpl/6-things-to-know-about-nasa…helicopter #CountdownToMars

Jul 14, 2020

These innovative seed cocoons help trees grow in the harshest climates

Posted by in categories: climatology, innovation

Land Life Company ❤


Boosting seedling survival rates from 10% to at least 90%.

For more on the Trillion Trees Challenge, visit UpLink: https://buff.ly/2O5nd3j

Jul 13, 2020

Coronavirus: Llamas provide key to immune therapy

Posted by in categories: biotech/medical, innovation

As Fifi the llama munches on grass on a pasture in Reading, her immune system has provided the template for a coronavirus treatment breakthrough.

Scientists from the UK’s Rosalind Franklin Institute have used Fifi’s specially evolved antibodies to make an immune-boosting therapy.

The resulting llama-based, Covid-specific “antibody cocktail” could enter clinical trials within months.

Jul 13, 2020

Nvidia brings Ampere A100 GPUs to Google Cloud

Posted by in categories: innovation, robotics/AI

Just over a month after announcing its latest generation Ampere A100 GPU, Nvidia said this week that the powerhouse processor system is now available on Google Cloud.

The A100 Accelerator Optimized VM A2 instance family is designed for enormous artificial intelligence workloads and . Nvidia says users can expect substantive improvements over previous processing models, in this instance up to a 20-fold performance boost. The system maxes out at 19.5 TFLOPS for single-precision performance and 156 TFLOPS for AI and computing applications demanding TensorFloat 32 operations.

The Nvidia Ampere is the largest 7 nanometer chip ever constructed. It sports 54 billion transistors and offers innovative features such as multi-instance GPU, automatic mixed precision, an NVLink that doubles GPU-to-GPU direct bandwidth and faster memory reaching 1.6 terabytes per second.

Jul 7, 2020

Israel invents one-minute coronavirus breath test

Posted by in categories: biotech/medical, innovation

The invention of an instant COVID-19 breathalyser could have enormous implications for air travel, with borders able to be re-opened and passengers mandatorily tested before flying.

Keeping NSW safe.

Jul 7, 2020

Cancer Screening Leaps Forward

Posted by in categories: biotech/medical, innovation

Innovation sneaks up on us: There’s a new DNA test that detects more illnesses, earlier.

Jul 6, 2020

Fuji envisions 400TB tape drive

Posted by in categories: computing, innovation

Fujifilm announced a technological breakthrough that will allow it to construct a massive 400 terabyte tape cartridge by the end of the decade.

Tape drives currently top out at about 12 terabytes of storage.

The Blocks and Files web site reported that Fujifilm says it can achieve the newer, greater capacities by switching from the standard Barium Ferrite (BaFe) tape coatings to Strontium Ferrite (SrFe).

Jul 5, 2020

Breakthrough Towards Lasers Powerful Enough to Investigate a New Kind of Physics

Posted by in categories: innovation, quantum physics

An international team of researchers has demonstrated an innovative technique for increasing the intensity of lasers.

In a paper that made the cover of the journal Applied Physics Letters, an international team of researchers has demonstrated an innovative technique for increasing the intensity of lasers. This approach, based on the compression of light pulses, would make it possible to reach a threshold intensity for a new type of physics that has never been explored before: quantum electrodynamics phenomena.

Researchers Jean-Claude Kieffer of the Institut national de la recherche scientifique (INRS), E. A. Khazanov of the Institute of Applied Physics of the Russian Academy of Sciences and in France Gérard Mourou, Professor Emeritus of the Ecole Polytechnique, who was awarded the Nobel Prize in Physics in 2018, have chosen another direction to achieve a power of around 1023 Watts (W). Rather than increasing the energy of the laser, they decrease the pulse duration to only a few femtoseconds. This would keep the system within a reasonable size and keep operating costs down.