It’s been a month since a Maryland man became the second person to receive a transplanted heart from a pig — and hospital video released Friday shows he’s working hard to recover.

Lawrence Faucette was dying from heart failure and ineligible for a traditional heart transplant when doctors at the University of Maryland School of Medicine offered the highly experimental surgery.

In the first glimpse of Faucette provided since the Sept. 20 transplant, hospital video shows physical therapist Chris Wells urging him to push through a pedaling exercise to regain his strength.

Researchers are attempting to uncover the basics of how fat tissue is structured and, specifically, inflammation associated with obesity, in the hopes of unlocking the connection between the accumulation of fat and poor health outcomes. Now, a new study by researchers at the University of Michigan revealed previously unrecognized immune cell types and interactions within adipose tissue using single-cell analysis of gene expression combined with spatial transcriptomics.

The findings are published in JCI Insight in an article titled, “A lipid-associated macrophage lineage rewires the spatial landscape of adipose tissue in early obesity.”

“Adipose tissue macrophage (ATM) infiltration is associated with adipose tissue dysfunction and insulin resistance in mice and humans,” wrote the researchers. “Recent single-cell data highlight increased ATM heterogeneity in obesity but do not provide a spatial context for ATM phenotype dynamics. We integrated single-cell RNA-Seq, spatial transcriptomics, and imaging of murine adipose tissue in a time course study of diet-induced obesity. Overall, proinflammatory immune cells were predominant in early obesity, whereas nonresident antiinflammatory ATMs predominated in chronic obesity.”

The human gut microbiome is known to have a significant influence on many aspects of our health. Usually, when people think of the gut microbiome, they think of the many bacterial species that live there. Other organisms like viruses and fungi are also members of the human gut microbiome that have been getting more research attention. Now, scientists have identified a unicellular organism called Blastocystis, a type of protist with many subtypes that are also a part of the human gut microbiome. The research has shown that different subtypes of Blastocystis can lead to beneficial health impacts while others are detrimental. The findings have been reported in The EMBO Journal.

People in Singapore have been found with a rare Blastocystis subtype called ST7, which is often isolated from patients with diarrhea. Blastocystis ST7 seems to cause gut disease, although the mechanisms that underlie this pathology have been unclear.