Lifeboat Foundation

Rusted iron pipes can react with residual disinfectants in drinking water distribution systems to produce carcinogenic hexavalent chromium in drinking water, reports a study by engineers at UC Riverside.

Chromium is a metal that occurs naturally in the soil and groundwater. Trace amounts of trivalent chromium eventually appear in the drinking water and food supply and are thought to have neutral effects on health. Chromium is often added to iron to make it more resistant to corrosion.

Certain chemical reactions can change chromium atoms into a hexavalent form that creates cancer-causing genetic mutations in cells. This carcinogenic form of chromium was at the heart of a lawsuit in California’s Central Valley by Erin Brockovich, which became the subject of an Oscar-winning movie.

A new study has found that a novel T cell genetically engineered by University of Arizona Health Sciences researchers is able to target and attack pathogenic T cells that cause Type 1 diabetes, which could lead to new immunotherapy treatments.

The immune system fights bacteria, viruses and other pathogens by utilizing several types of T cells, all of which have receptors that are specific to particular antigens. On killer T cells, the receptor works in concert with three signaling modules and a coreceptor to destroy the infected cell. Michael Kuhns, Ph.D., an associate professor in the UArizona College of Medicine—Tucson Department of Immunobiology, copied the evolutionary design to engineer a five-module chimeric antigen receptor, or 5MCAR, T cell.

“The 5MCAR was an attempt to figure out if we could build something by biomimicry, using some of evolution’s natural pieces, and redirect T cells to do what we want them to do. We engineered a 5MCAR that would direct killer T cells to target autoimmune T cells that mediate Type 1 diabetes,” said Dr. Kuhns, who is member of the UArizona Cancer Center, BIO5 Institute and Arizona Center on Aging. “So now, a killer T cell will actually recognize another T cell. We flipped T cell-mediated immunity on its head.”

“BAT said KBP had cloned a portion of the genetic sequence of coronavirus and developed a potential antigen, which is then inserted into tobacco plants for reproduction.”

😲😲😲

While large pharmaceutical companies are already producing vaccines, [the company British American Tobacco] believes its own can be produced in six weeks, compared with the several months it takes using conventional methods.

Continue reading “COVID vaccine made from GMO tobacco? It’s now in human trials” »

“The research was conducted by overexpressing two different genes, the AVP1 and OsSIZ1.”

😯😯😯

One group of Texas Tech University researchers has found a way to double fiber yield for cotton in semi-arid areas like that of West Texas, where drought, heat and salinity are working against farmers.

Continue reading “Tweaking two genes in cotton doubles crop yields—and may do the same in wheat, rice and corn” »

Mice, fruit flies and dogs are common creatures of laboratories across the country, valuable to researchers for their genetic proximity to humans. But what about lampreys?

A new Yale School of Public Health study has enlisted this unlikely and slimy ally in the fight against cancer.

By carefully tracing the evolution of a select number of cancer-causing genes in a variety of species, the researchers evaluated which animals are—and are not—effective in gauging how an analog of those genes in humans can lead to cancer. What they found is surprising: jawless fish such as lampreys share significant similarities in these certain genes compared to humans, while fruit flies do not. Their findings, published in the journal Genome Biology and Evolution, will help molecular biologists and other scientists as they work to find potential cures to certain cancers, such as lymphoma.

All hail the powerful One climbed my wood structure that went straight up then went to the roof o.o. Also their hands make them like chimps.

How does intelligence ofs compare with other species? That was a topic of heated debate between 1905 and 1915 within the then-nascent field of comparative psychology.

In 1907, psychologist Lawrence W. Cole, who had established a colony ofs at the University of Oklahoma, and Herbert Burnham Davis, a doctoral student at Clark University, each published the results of nearly identical experiments on the processes of learning, association and memory ins. They relied on E.L. Thorndike’s puzzle-box methodology, which involved placing animals in wooden crates from which the animal had to escape by opening the latch or sequence of latches. They observed the number of trials required for successful completion and the extent to which the animal retained the ability to solve the same problem more quickly when confronted again with it. Using this method, they sought what Davis called “a tolerable basis” for ranking the intelligence ofs on the phylogenetic scale of evolutionary development. They independently concluded thats bested the abilities of cats and dogs, most closely approximating the mental attributes of monkeys.

Continue reading “Raccoon intelligence at the borderlands of science” »

Researchers have identified a cancer-causing mutation in the PDGFRA gene that drives cell mutation and growth when activated. The findings have implications for the treatment of a subset of glioblastoma brain cancer.

As the first patient to receive an experimental treatment that relied on the gene-editing technique CRISPR continues to do well 17 months later, more patients seem to be benefiting, too.

I think I want non-gene hacked pigs for my supper. 😃

For the second time ever, the U.S. Food and Drug Administration (FDA) approved a gene-hacked animal for human consumption.

In this case, it’s the GalSafe pig, CNN reports, a genetically modified swine that’s safe even for people with allergies to eat. All in all, it’s a fresh sign that genetically-altered animals and sophisticated gene-hacking technology are now becoming commercially viable and entering the mainstream.

Continue reading “FDA Approves Gene-Hacked Pigs for Human Consumption” »