Lifeboat Foundation

Genetic engineering and other advanced technologies may need to come into play if people want to live in Mars.

Last month’s NASA and SpaceX successful launch of astronauts from US soil for the first time in almost a decade, has reignited discussion about space travel to Mars and beyond. SpaceX is fronted by the billionaire Elon Musk.

Continue reading “Elon Musk makes getting humans to Mars his top priority” »

True genetic isolation is hard to pull off. Human populations tend to mix when they are in close proximity.

Consider the Hui people. These are Muslims who live across China and speak the local Chinese dialect of their locale. The Hui claim descent from Central Asians and Persians who arrived in China around 1,000 years ago. But the vast majority of their genomes are no different from the Han Chinese. Physically they are impossible to distinguish from Han Chinese unless you take note of their attire.

How can that be when they are so culturally different? For example, as Muslims the Hui do not eat pork and consider it unclean. In contrast, for the majority Han pork is dietary staple.

One day, cell and gene therapies will be as common as small molecules and antibody-based therapies are today, according to panelists at BIO’s June 8 virtual session, “The Next Generation of Medicine: Cell Therapies, Gene Therapies and Beyond.”

Because cell and gene therapies have the potential to address complex biological issues such as dysregulation, translocation and mutations, they can use that power to change what the body is doing.

“So, while small molecules and antibody therapies will still be around 30 years from now, they will be less important. Cell and gene therapies will dominate,” James Sabry, global head of pharma partnering at Roche, said.

Circa 2017

Unlike other animals, cephalopods – the family that includes octopuses, squid and cuttlefish – do not obey the commands of their DNA to the letter.

Instead, they sometimes interfere with the code as it is being carried by a molecular “messenger”. This has the effect of diversifying the proteins their cells can produce, leading to some interesting variations.

Continue reading “Squid and octopus can edit and direct their own brain genes” »

The personal genomics and biotechnology company 23andMe is perhaps best known for its home DNA testing kits, whereby consumers can learn about their genetic make-up or ancestry.

However, after the COVID-19 outbreak was declared a global pandemic, the company switched gears and looked to see how their gene testing services could offer a helping hand in understanding the disease’s pathophysiology.

One aspect of COVID-19 that has puzzled scientists and clinicians alike is why, when infected with SARS-CoV-2, do some patients display mild to moderate symptoms (or no symptoms at all), whereas other patients develop severe symptoms that can prove fatal?

Experts wonder how genetic engineering will eventually reshape the natural world.

The president also ordered a boost in the education of specialists in genetics and genome sequencing and the domestic production of necessary laboratory equipment, as well as tax cuts for biomedical research. Russia will also open world-class genome research centers which will, among their immediate goals, work on the development of treatments and vaccines for Covid-19.

The future database will be one of the tools that Russia hopes to use to assume a leading position in the biomedical industry. The government sees it as crucial for keeping the country competitive on the world stage going forward.

The Kurchatov Institute, which is best known for nuclear research, has been tasked with laying the foundation for the database, choosing the storage format and making tools for search and analysis. The institute has experience in the secure handling of large amounts of sensitive data and operates a number of data centers across Russia which are used for scientific collaboration projects.

For the first time, Italian scientists have been able to identify the genetic and molecular basis of this susceptibility to infection as well as to the possibility of contracting a more severe form of the disease. The research will be presented to the 53rd annual conference of the European Society of Human Genetics, being held entirely on-line due to the Covid-19 pandemic, today [Saturday].