Acetate helps the female rodents form memories but is less effective in males.
Category: futurism – Page 65
Claude Code Flaws Allow Remote Code Execution and API Key Exfiltration
Claude Code flaws allow remote code execution and API key theft via untrusted repositories; three bugs fixed across 2025–2026 releases.
Lack of PCK1 in hepatic stellate cells causes liver fibrosis by fueling tricarboxylic acid cycle and increasing glycolysis
Online now: This study shows that a key metabolic enzyme, PCK1, protects the liver from scarring by keeping fibrogenic cells in a quiescent state. When PCK1 is reduced, these cells undergo metabolic reprogramming characterized by increased glycolysis, become aberrantly activated, and promote liver fibrosis in mice.
Electromotility can be disassociated from gating charge movement in outer hair cells of conditional alpha2 spectrin knockout mice
New in JBC press| Scientists examine the effects of conditional knockouts of alpha2 spectrin in postnatal outer hair cells.
asbmbJBC.
Electromotility in mammalian outer hair cells (OHC) is the mechanism underlying cochlear amplification. It is brought about by the piezoelectric-like property of the membrane protein prestin (Slc26a5) that lies in the OHCs lateral plasma membrane. Prestin connects to an underlying cytoskeletal network of circumferential actin filaments that bridge longitudinal spectrin filaments. This network, in turn, lies between the plasma membrane and a closely apposed ER-like tubular array of subsurface cisternae (SSC).
