Allows for more easily building tiny machines, biomedical sensors, optical computers, solar panels, and other devices — no complex clean room required; portable version planned.
Illustration of the bubble-pen pattern-writing process using an optically controlled microbubble on a plasmonic substrate. The small blue spheres are colloidal nanoparticles. (credit: Linhan Lin et al./Nano Letters)
Researchers in the Cockrell School of Engineering at The University of Texas at Austin have created “bubble-pen lithography” — a device and technique to quickly, gently, and precisely use microbubbles to “write” using gold, silicon and other nanoparticles between 1 and 100 nanometers in size as “ink” on a surface.
The new technology is aimed at allowing researchers to more easily build tiny machines, biomedical sensors, optical computers, solar panels, and other devices.



Last week at CES, South San Francisco based Profusa showed off an upcoming injectable sensor that can be used to continuously monitor oxygen levels in tissue. Measuring only five millimeters long and a tiny 250 microns in diameter, the biosensor can be injected into tissue with just a hypodermic needle. It consists of a soft hydrogel scaffold that allows it to be biologically compatible with the surrounding tissue without any foreign body response. The sensor also contains a special chemical marker that changes fluorescence depending on the amount of oxygen that reacts with it. An optical reader placed on the skin measures the fluorescence and relays the data to a smartphone. The biosensor can last as long as two years (at which point the chemical marker begins to lose its potency), and because it contains no electronics and is completely biocompatible there’s no need to remove it.


