Lifeboat Foundation

A bitter divorce battle in Russia has led to cryogenically frozen bodies being seized in an extraordinary day-time raid.

Staff of a company set up by Valeria Udalova, 59 grabbed the remains of people — including from Britain and the US — who paid thousands of pounds hoping to be brought back to life when science advances to allow this.

She and her team raided the company run by her ex-husband Danila Medvedev, 41 near Moscow, which is home to Russia’s leading cryo-storage facility, say reports.

2021 Cryonics Institute Annual General Meeting SUNDAY — SEPT 12 2021.

ZOOM Virtual Meeting CI will be live-streaming the meeting on Zoom.

Registration is free:

Continue reading “Welcome! You are invited to join a webinar: Cryonics Institute AGM. After registering, you will receive a confirmation email about joining the webinar” »

Since 1,988 and formation of the Posthuman Movement, and articles by early adopters like Max Moore were a sign our message was being received — although I always argued on various Extropian & Transhuman bulletin boards & Yahoo groups &c that “Trans” was a redundant middle and we should move straight to Posthuman, now armed with the new MVT knowledge (also figures on the CDR). There will be a new edition of World Philosophy, the first this millennium, to coincided with various Posthuman University events later this year. Here is the text:

THE EXTROPIAN PRINCIPLES V. 2.01 August 7 1992.

Max More Executive Director, Extropy Institute.

Continue reading “This 1,992 paper was included on best-selling CDR World Philosophy compilation (before internet) and I claim some credit for circulated it and popularising the ‘Transhuman sidetrack’” »

Check out our new promo for #transvision #future Summit 2021! Get your tickets! -> www.TransVisionMadrid.com There will be talks about #longevity #artificialintelligence #cryonics and much much more. You will also be able to network with speakers and attendees during 5 optional dinner/cocktails, and 2 tours of several UNESCO heritage sites and historical places: Ávila, Segovia, Monsaterio de El Escorial, Valle de los Caídos (Valley of the Fallen), Aranjuez & Toledo.

Humanity Plus Humanity Plus Humanity Plus Magazine MUTISHAN Interactive Vivian Francos #SEOHashtag Alcor Life Extension Foundation Cryonics Institute Cryonics Institute SENS Research Foundation SENS Research Foundation Posthuman Network Posthuman Network Cryonics4U Longevity Conferences Longevity for All U.S. Transhumanist Party Transhumanist Party Australia Transhumanist Party Virtual Rational Transhumanism Singularity University Ray Kurzweil Singularity Singularity Hub Ray Kurzweil’s Singularity Singularity Network Transhumanismo Brasil Transhumanismo Brasil TRANSHUMANISMO Christian Transhumanist Association Mormon Transhumanist Association SingularityNET Singularitarianism Foresight Institute Lifeboat Foundation Lifeboat Foundation Machine Intelligence Research Institute KrioRus The Hedonistic Imperative — Paradise Engineering.

Continue reading “#TransVision Future Summit 2021 — Promo 1 (English)” »

Sun, Sep 12 at 12 PM PDT.

This is an invitation to the Annual General Meeting of the Cryonics Institute & the Immortalist Society.

The Cryonics Institute, Annual General Meeting (AGM) will be held at 3:00pm to 6:30pm on Sunday, September 12th, 2021 at the Infinity Hall 16650 E. 14 Mile Rd, Fraser, MI 48026 (USA) for more information visit www.infinityhallsidebar.com or call 586−879−6157. Tours at the CI facility will be from 1:00pm to 2:30pm 24355 Sorrentino Court, Clinton Township, (Michigan) 48035 (USA).

Continue reading “CI Annual General Meeting 2021” »

When an 87-year-old Californian man was wheeled into an operating room just outside Phoenix last year, the pandemic was at its height and medical protocols were being upended across the country.

A case like his would normally have required 14 or more bags of fluids to be pumped into him, but now that posed a problem.

Had he been infected with the coronavirus, tiny aerosol droplets could have escaped and infected staff, so the operating team had adopted new procedures that reduced the effectiveness of the treatment but used fewer liquids.

The resulting implant consists of cells attached to the scaffold, which permits the targeted delivery of therapeutic cells to the diseased region within the eye. A non-cryopreserved formulation of this cellular therapy is being employed in an ongoing Phase I/IIa clinical trial sponsored by RPT. The cryopreserved formulation enabled by the work of Pennington and colleagues will facilitate anticipated Phase IIb and Phase III clinical trials as well as ultimate commercialization and clinical application of the product.

Scientists at UC Santa Barbara, University of Southern California (USC), and the biotechnology company Regenerative Patch Technologies LLC (RPT) have reported new methodology for preservation of RPT’s stem cell-based therapy for age-related macular degeneration (AMD).

The new research, recently published in Scientific Reports, optimizes the conditions to cryopreserve, or freeze, an implant consisting of a single layer of ocular cells generated from human embryonic stem cells supported by a flexible scaffold about 3×6 mm in size. This implant is currently in clinical trial for the treatment of AMD, the leading cause of blindness in aging populations. The results demonstrate that the implant can be frozen, stored for long periods and distributed in frozen form to clinical sites where it is designed to be thawed and immediately implanted into the eyes of patients with macular degeneration. The capacity to cryopreserve this and other cell-based therapeutics will extend shelf life and enable on-demand distribution to distant clinical sites, increasing the number of patients able to benefit from such treatments.

Continue reading “A frozen leap forward for age-related macular degeneration stem cell-based therapy” »

Circa 2015 brain immortality through aldehyde stabilized cryopreservation.

We describe here a new cryobiological and neurobiological technique, aldehyde-stabilized cryopreservation (ASC), which demonstrates the relevance and utility of advanced cryopreservation science for the neurobiological research community. ASC is a new brain-banking technique designed to facilitate neuroanatomic research such as connectomics research, and has the unique ability to combine stable long term ice-free sample storage with excellent anatomical resolution. To demonstrate the feasibility of ASC, we perfuse-fixed rabbit and pig brains with a glutaraldehyde-based fixative, then slowly perfused increasing concentrations of ethylene glycol over several hours in a manner similar to techniques used for whole organ cryopreservation. Once 65% w/v ethylene glycol was reached, we vitrified brains at −135 °C for indefinite long-term storage. Vitrified brains were rewarmed and the cryoprotectant removed either by perfusion or gradual diffusion from brain slices. We evaluated ASC-processed brains by electron microscopy of multiple regions across the whole brain and by Focused Ion Beam Milling and Scanning Electron Microscopy (FIB-SEM) imaging of selected brain volumes. Preservation was uniformly excellent: processes were easily traceable and synapses were crisp in both species. Aldehyde-stabilized cryopreservation has many advantages over other brain-banking techniques: chemicals are delivered via perfusion, which enables easy scaling to brains of any size; vitrification ensures that the ultrastructure of the brain will not degrade even over very long storage times; and the cryoprotectant can be removed, yielding a perfusable aldehyde-preserved brain which is suitable for a wide variety of brain assays.

As part of preparing for an experiment aboard the International Space Station, researchers explored new ways to culture living heart cells for microgravity research. They found that cryopreservation, a process of storing cells at-80°C, makes it easier to transport these cells to the orbiting lab, providing more flexibility in launch and operations schedules. The process could benefit other biological research in space and on Earth.

The investigation, MVP Cell-03, cultured heart precursor cells on the space station to study how microgravity affects the number of cells produced and how many of them survive. These precursor cells have potential for use in disease modeling, drug development, and regenerative medicine, such as using cultured heart cells to replenish those damaged or lost due to cardiac disease.

Previous studies suggest that culturing such cells in simulated microgravity increases the efficiency of their production. But using live cell cultures in space presents some unique challenges. The MVP Cell-03 experiment, for example, must be conducted within a specific timeframe, when the cells are at just the right stage. Flight changes and crew availability could lead to delays that affect the research.