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Astronomers spot methanol in a weird part of the galaxy, changing where they might hunt for aliens

They’ve only gone and upended a widely held scientific idea.


Lilia Koelemay, a graduate researcher at the University of Arizona, said in a statement about the study that “the detection of these organic molecules at the galactic edge may imply that organic chemistry is still prevalent at the outer reaches of the galaxy, and the [galatic habitable zone] may extend much further from the galactic center than the currently established boundary.”

Koelemay also said, “The widely held assumption was that in the outskirts of our galaxy, the chemistry necessary to form organics just doesn’t occur.”

What’s next — The new finding overturns this assumption, and researchers can now widen the search for life to stars closer to the galaxy’s outer edge, a no-man’s-land of cold matter, isolated stars, and black holes left from long-ago stellar explosions. It’s a place Koelemay says has fewer stars like our life-giving Sun.

Quantum computing is inevitable, cryptography prepares for the future

Quantum computing began in the early 1980s. It operates on principles of quantum physics rather than the limitations of circuits and electricity which is why it is capable of processing highly complex mathematical problems so efficiently. Quantum computing could one day achieve things that classical computing simply cannot. The evolution of quantum computers has been slow, but things are accelerating, thanks to the efforts of academic institutions such as Oxford, MIT, and the University of Waterloo, as well as companies like IBM, Microsoft, Google, and Honeywell.

IBM has held a leadership role in this innovation push and has named optimization as the most likely application for consumers and organizations alike.

Honeywell expects to release what it calls the “world’s most powerful quantum computer” for applications like fraud detection, optimization for trading strategies, security, machine learning, and chemistry and materials science.

Age Resetting Genes Going to Human Studies in Two Years

David Sinclair is a geneticist at Harvard and author of Lifespan.

Nature – Reversal of biological clock restores vision in old mice

Sinclair and his team restored vision in old mice and in mice with damaged retinal nerves by resetting some of the thousands of chemical marks that accumulate on DNA as cells age. They are now working to rejuvenate the brains of old mice. This work is so promising that Sinclair believes he can get to human trials within two years. Sinclair is using three genes to reset the age of cells.

Arctic rotifer lives after 24,000 years in a frozen state

Bdelloid rotifers are multicellular animals so small you need a microscope to see them. Despite their size, they’re known for being tough, capable of surviving through drying, freezing, starvation, and low oxygen. Now, researchers reporting in the journal Current Biology on June 7 have found that not only can they withstand being frozen, but they can also persist for at least 24000 years in the Siberian permafrost and survive.

“Our report is the hardest proof as of today that multicellular animals could withstand tens of thousands of years in cryptobiosis, the state of almost completely arrested metabolism,” says Stas Malavin of the Soil Cryology Laboratory at the Institute of Physicochemical and Biological Problems in Soil Science in Pushchino, Russia.

The Soil Cryology Lab specializes in isolating from the ancient permafrost in Siberia. To collect samples, they use a in some of the most remote Arctic locations.

Aldehyde-stabilized cryopreservation

Circa 2015 brain immortality through aldehyde stabilized cryopreservation.


We describe here a new cryobiological and neurobiological technique, aldehyde-stabilized cryopreservation (ASC), which demonstrates the relevance and utility of advanced cryopreservation science for the neurobiological research community. ASC is a new brain-banking technique designed to facilitate neuroanatomic research such as connectomics research, and has the unique ability to combine stable long term ice-free sample storage with excellent anatomical resolution. To demonstrate the feasibility of ASC, we perfuse-fixed rabbit and pig brains with a glutaraldehyde-based fixative, then slowly perfused increasing concentrations of ethylene glycol over several hours in a manner similar to techniques used for whole organ cryopreservation. Once 65% w/v ethylene glycol was reached, we vitrified brains at −135 °C for indefinite long-term storage. Vitrified brains were rewarmed and the cryoprotectant removed either by perfusion or gradual diffusion from brain slices. We evaluated ASC-processed brains by electron microscopy of multiple regions across the whole brain and by Focused Ion Beam Milling and Scanning Electron Microscopy (FIB-SEM) imaging of selected brain volumes. Preservation was uniformly excellent: processes were easily traceable and synapses were crisp in both species. Aldehyde-stabilized cryopreservation has many advantages over other brain-banking techniques: chemicals are delivered via perfusion, which enables easy scaling to brains of any size; vitrification ensures that the ultrastructure of the brain will not degrade even over very long storage times; and the cryoprotectant can be removed, yielding a perfusable aldehyde-preserved brain which is suitable for a wide variety of brain assays.

A new material made from carbon nanotubes can generate electricity

MIT engineers have discovered a new way of generating electricity using tiny carbon particles that can create a current simply by interacting with liquid surrounding them.

The liquid, an , draws electrons out of the particles, generating a current that could be used to drive or to power micro-or nanoscale robots, the researchers say.

“This mechanism is new, and this way of generating is completely new,” says Michael Strano, the Carbon P. Dubbs Professor of Chemical Engineering at MIT. “This technology is intriguing because all you have to do is flow a solvent through a bed of these particles. This allows you to do electrochemistry, but with no wires.”

New tech cheaply produces lithium and H2, while desalinating seawater

With the rise of the lithium-based battery, demand for this soft, silvery-white metal – the lightest solid element in the periodic table – has exploded. With the race to zero carbon by 2050 gathering steam, forcing the electrification of transport, lithium will be an even more valuable asset in the next 30 years.

The supply of raw materials for batteries could even end up being a national security issue, too; China’s global leadership on high-volume EV production has put it ahead of the game, and while the majority of ground-based lithium reserves are in the “lithium triangle” of Chile, Bolivia and Argentina, China controls more than half’s the world’s supply simply through investments and ownership. It has shown in the past that it’s not afraid to wield commodity supplies as a weapon.

But as with other metals like uranium, land-based lithium reserves pale in comparison to what’s out there in the sea. According to researchers at Saudi Arabia’s King Abdullah University of Science and Technology (KAUST), there’s about 5000 times as much lithium in the oceans as there is in land deposits, and a newly developed technology could start extracting it cheaply enough to make the big time – while producing hydrogen gas, chorine gas and desalinated water as a bonus.

Smashing gold with finesse: Shockless compression experiments establish new pressure scales

To test the Standard Model of particle physics, scientists often collide particles using gigantic underground rings. In a similar fashion, high-pressure physicists compress materials to ever greater pressures to further test the quantum theory of condensed matter and challenge predictions made using the most powerful computers.

Pressures exceeding 1 million atmospheres are capable of dramatically deforming atomic electronic clouds and alter how atoms are packed together. This leads to new chemical bonding and has revealed extraordinary behaviors such as helium rain, the transformation of sodium into a transparent metal, the emergence of superionic water ice and the transformation of hydrogen into a metallic fluid.

With new techniques constantly advancing the frontier of high– physics, terapascal (TPa) pressures that were once inaccessible can now be achieved in the laboratory using static or dynamic compression (1 TPa is equivalent to approximately 10 million atmospheres).

A catalyst that destroys perchlorate in water could clean Martian soil

## JOURNAL OF THE AMERICAN CHEMICAL SOCIETY • JUN 4, 2021.

# *A lovely single step bio-inspired process with some interesting complex benefits particularly for humans on Mars.*

*by holly ober, university of california — riverside*

A team led by UC Riverside engineers has developed a catalyst to remove a dangerous chemical from water on Earth that could also make Martian soil safer for agriculture and help produce oxygen for human Mars explorers.

Perchlorate, a negative ion consisting of one chlorine atom bonded to four oxygen atoms, occurs naturally in some soils on Earth, and is especially abundant in Martian soil. As a powerful oxidizer, perchlorate is also manufactured and used in solid rocket fuel, fireworks, munitions, airbag initiators for vehicles, matches and signal flares. It is a byproduct in some disinfectants and herbicides.

Because of its ubiquity in both soil and industrial goods, perchlorate is a common water contaminant that causes certain thyroid disorders. Perchlorate bioaccumulates in plant tissues and a large amount of perchlorate found in Martian soil could make food grown there unsafe to eat, limiting the potential for human settlements on Mars. Perchlorate in Martian dust could also be hazardous to explorers. Current methods of removing perchlorate from water require either harsh conditions or a multistep enzymatic process to lower the oxidation state of the chlorine element into the harmless chloride ion.

Doctoral student Changxu Ren and Jinyong Liu, an assistant professor of chemical and environmental engineering at UC Riverside’s Marlan and Rosemary Bourns College of Engineering, took inspiration from nature to reduce perchlorate in water at ambient pressure and temperature in one simple step.

Sonothermogenetics for noninvasive and cell-type specific deep brain neuromodulation

Critical advances in the investigation of brain functions and treatment of brain disorders are hindered by our inability to selectively target neurons in a noninvasive manner in the deep brain.

This study aimed to develop sonothermogenetics for noninvasive, deep-penetrating, and cell-type-specific neuromodulation by combining a thermosensitive ion channel TRPV1 with focused ultrasound (FUS)-induced brief, non-noxious thermal effect.

The sensitivity of TRPV1 to FUS sonication was evaluated in vitro. It was followed by in vivo assessment of sonothermogenetics in the activation of genetically defined neurons in the mouse brain by two-photon calcium imaging. Behavioral response evoked by sonothermogenetic stimulation at a deep brain target was recorded in freely moving mice. Immunohistochemistry staining of ex vivo brain slices was performed to evaluate the safety of FUS sonication.