Addressing the staggering power and energy demands of artificial intelligence, engineers at the University of Houston have developed a revolutionary new thin-film material that promises to make AI devices significantly faster while dramatically cutting energy consumption.
The breakthrough, detailed in the journal ACS Nano, introduces a specialized two-dimensional (2D) thin film dielectric —or an electric insulator—designed to replace traditional, heat generating components in integrated circuit chips. This new thin film material, which does not store electricity, will help reduce the significant energy cost and heat produced by the high-performance computing necessary for AI.
“AI has made our energy needs explode,” said Alamgir Karim, Dow Chair and Welch Foundation Professor at the William A. Brookshire Department of Chemical and Biomolecular Engineering at UH.
A chromosome pulled from the flowers of Arabidopsis thaliana (green and white) unspools to reveal DNA (blue) coiled around packaging-proteins called histones (purple). The direction of epigenetic changes by genetic features begins as the RIM transcription factor (pink) docks on a corresponding DNA sequence (pink). Once docked, the RIM transcription factor directs methylation machinery to tack methyl groups (orange) onto specific nearby cytosines (orange). Click here for a high-resolution image. Credit: Salk Institute.
All the cells in an organism have the exact same genetic sequence. What differs across cell types is their epigenetics—meticulously placed chemical tags that influence which genes are expressed in each cell. Mistakes or failures in epigenetic regulation can lead to severe developmental defects in plants and animals alike. This creates a puzzling question: If epigenetic changes regulate our genetics, what is regulating them?
Scientists at the Salk Institute have now used plant cells to discover that a type of epigenetic tag, called DNA methylation, can be regulated by genetic mechanisms. This new mode of plant DNA methylation targeting uses specific DNA sequences to tell the methylation machinery where to dock. Prior to this study, scientists had understood only how DNA methylation was regulated by other epigenetic features, so the discovery that genetic features can also guide DNA methylation patterns is a major paradigm shift.
Scientists at EPFL have created a scalable 3D organoid model that captures key features of early limb development, revealing how a specialized signaling center shapes both cell identity and tissue organization.
During early development, the embryo builds the body’s organs by exchanging chemical signals between different cell types. When developing limbs, a thin band of skin cells at the limb’s surface, called the “apical ectodermal ridge” (AER), sends signals that guide the underlying population as it grows and forms bone, cartilage, and connective tissue.
The AER is hard to study because it forms only briefly in the embryo and secretes several types of signaling molecules at once. Studying these interactions in embryos is difficult, so scientists often turn to organoids, tiny lab-grown organs that offer researchers a controlled way to study how cells behave and interact as tissues form.
A Johns Hopkins Medicine study involving a dozen people with the inflammatory skin disease hidradenitis suppurativa (HS), which mostly affects skin folds, is believed to be the first to provide evidence that hormone-disrupting chemicals commonly found in ultra-processed food and single-use water bottles may contribute to the development of or worsen the condition in some people.
The new findings about the disorder build on previous reports about the role of endocrine-disrupting chemicals, a common environmental contaminant known to mimic, block or alter the body’s hormones, in human health. Researchers believe their findings suggest that reducing exposure could ease HS symptom severity and provide a new avenue of relief for a disease with limited FDA-approved treatment options that include biologic therapy and surgery.
The full report on the study was published in Nature Communications on Nov. 28 and includes insights into the molecular mechanisms that are involved in the disease.
By analyzing the data from the SuperCOSMOS Hα Survey (SHS) and from the Gaia satellite, astronomers have inspected a bipolar planetary nebula designated PHR J1724-3859. Results of the study, published Nov. 19 on the arXiv pre-print server, deliver crucial insights into the properties of this nebula.
Planetary nebulae (PNe) are the final stages of evolution of low-to-intermediate mass stars. They are expanding shells of gas and dust that have been ejected from a star during the process of its evolution from a main sequence star into a red giant or white dwarf. PNe are relatively rare, but important for astronomers studying the chemical evolution of stars and galaxies.
Thermosets, such as epoxy and silicon rubbers, are a class of polymer (i.e., plastic) materials that harden permanently when they undergo a specific chemical reaction, known as “crosslinking.” These materials are highly durable, heat-resistant with excellent electrical insulation in various applications such as in adhesives, coatings, and automotive parts.
Thermosets are also widely used to fabricate electronic components, including switches, circuit breakers and other core circuit components.
So far, thermoset-based free-standing devices have proved difficult to construct by using conventional 3D printing processes. One key reason for this is that the materials need to be provisionally supported by other supporting objects until they become solid, which adds more steps to the printing process.
Chemical rockets have taken us to the moon and back, but traveling to the stars demands something more powerful. Space X’s Starship can lift extraordinary masses to orbit and send payloads throughout the solar system using its chemical rockets, but it cannot fly to nearby stars at 30% of light speed and land. For missions beyond our local region of space, we need something fundamentally more energetic than chemical combustion, and physics offers, or, in other words, antimatter.
When antimatter encounters ordinary matter, they annihilate completely, converting mass directly into energy according to Einstein’s equation E=mc². That c² term is approximately 10¹⁷, an almost incomprehensibly large number. This makes antimatter roughly 1,000 times more energetic than nuclear fission, the most powerful energy source currently in practical use.
As a source of energy, antimatter can potentially enable spacecraft to reach nearby stars at significant fractions of the speed of light. A detailed technical analysis by Casey Handmer, CEO of Terraform Industries, outlines how humanity could develop practical antimatter propulsion within existing spaceflight budgets, requiring breakthroughs in three critical areas; production efficiency, reliable storage systems, and engine designs that can safely harness the most energetic fuel physically possible.
Leukemia starts when mutations in blood-forming cells disrupt the balance between growth and differentiation. Patients with entirely different genetic changes show strikingly similar patterns of gene activity and can respond to the same drugs. What invisible thread could make so many mutations behave the same way?
The authors looked into high-resolution microscope and saw something no one expected: leukemia cell nuclei shimmered with a dozen bright dots – tiny beacons missing from healthy cells.
Those dots weren’t random. They contained large amounts of mutant leukemia proteins and drew in many normal cell proteins to coordinate activation of the leukemia program. The dots were new nuclear compartments formed by phase separation, the same physical principle that describes why oil droplets form in water. The team named this new compartment, “coordinating bodies,” or C-bodies.
Inside the nucleus, these C-bodies act like miniature control rooms, pulling together the molecules that keep leukemia genes switched on. Like drops of oil collecting on the surface of soup, they appear when the cell’s molecular ingredients reach just the right balance.
Even more surprising, cells carrying entirely different leukemia mutations formed droplets with the same behavior. Although their chemistry differs, the resulting nuclear condensates perform the same function, using the same physical playbook.
A new quantitative assay confirmed it. These droplets are biophysically indistinguishable – like soups made from different ingredients that still simmer into the same consistency. No matter which mutation started the process, each leukemia formed the same kind of C-body.
The team confirmed the finding across human cell lines, mouse models and patient samples. When they tweaked the proteins so they could no longer form these droplets – or dissolved them with drugs, the leukemia cells stopped dividing and began to mature into healthy blood cells.
Soft robots are prized for their agility and gentle touch, which makes them ideal for traversing delicate or enclosed spaces to perform various tasks, from cultivating baby corals in laboratories to inspecting industrial pipes in chemical plants. However, achieving embodied intelligence in such systems, where sensing, movement and power supply work together in an untethered configuration, remains a challenge.
Flexible materials can deform and adapt, but their power sources are unable to do so. Conventional batteries often stiffen the robot’s body, drain quickly, or degrade under strain, all of which leave soft robots tethered or with a short lifespan.
Assistant Professor Wu Changsheng and his team from the Department of Materials Science and Engineering and the Department of Electrical and Computer Engineering, College of Design and Engineering, National University of Singapore, found a way to turn that limitation into an advantage. Their study, published in Science Advances, demonstrates that the same magnetic fields used to control soft robots can also enhance the performance of the batteries inside them.
