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Category: biotech/medical – Page 4

A potential replacement for bone marrow sampling: New blood test may detect leukemia risk

What if a blood test could reveal the pace of our aging—and the diseases that may lie ahead? The labs of Profs. Liran Shlush and Amos Tanay at the Weizmann Institute of Science have been conducting in-depth studies into the biology of blood to better understand the aging process and why some people become more susceptible to disease over the years.

Their research teams, made up of physicians, biologists and , have been tracking changes in the , including the emergence of genetic changes in these cells in about one-third of people over the age of 40. These changes not only increase the risk of blood cancers such as leukemia, but have also been linked to heart disease, diabetes and other age-related conditions.

In a new study published today in Nature Medicine, Shlush and Tanay present findings that may lead to an innovative for detecting a person’s risk of developing leukemia. This test may potentially replace the invasive diagnostic procedure of bone marrow sampling.

Rewriting DNA- from Fiction to Reality

Gene therapy—once something out of science fiction—is now being used in real hospitals to treat real people. Gene editing has become a conversation of not only treating rare diseases but also about access, fairness, and how much control we should have over our biology.

Genes are sections of DNA that act like instruction manuals telling our cells how to build proteins. Proteins perform vital function like energy use, cellular communications, immunity and cell repair. So when people say “We are what our genes make us,” it’s because these gene-coded proteins guide our growth, health, and behaviour.

Sometimes, typos appear in these instruction manuals. They are called genetic mutations. While many mutations are harmless, some affect the protein made from the mutated gene and disrupt how the cell functions. Some cause serious diseases like cystic fibrosis, muscular atrophy or certain cancers.

From Mammoth Revival to Human Fertility with Dr. Eriona Hysolli | Singularity University

Join us for an exclusive 1-hour conversation with Dr. Eriona Hysolli, the visionary scientist bridging de-extinction technology and the future of human reproduction. Recognized by Time100 Next for her groundbreaking work reviving the woolly mammoth, Dr. Hysolli brings a unique perspective to reproductive biotechnology that you won’t find anywhere else.

In this informal Q&A session, we’ll explore how cutting-edge technologies originally developed for species conservation are now revolutionizing human fertility treatments. Dr. Hysolli will share insights on:
The latest breakthroughs in synthetic embryos and artificial wombs.
How in vitro gametogenesis could transform infertility treatment.
Lessons from mammoth de-extinction that apply to human reproductive health.
The intersection of genome engineering and fertility solutions.
Near-term commercial applications in reproductive biotechnology.

Drawing from her pioneering work at Yale, George Church’s lab at Harvard, and as Head of Biological Sciences at Colossal Biosciences, Dr. Hysolli offers a rare glimpse into technologies that could redefine human reproduction within the next decade.

The session will feature a moderated discussion followed by audience Q&A. Whether you’re an investor, entrepreneur, healthcare professional, or simply fascinated by the future of fertility, this conversation will provide essential insights into one of biotechnology’s most promising frontiers.

Subscribe: http://bit.ly/1Wq6gwm.

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Light-powered microscopic swimmers with on/off control open new pathways for drug delivery

Scientists have created tiny disk-shaped particles that can swim on their own when hit with light, akin to microscopic robots that move through a special liquid without any external motors or propellers.

Published in Advanced Functional Materials, the work shows how these artificial swimmers could one day be used to deliver cargo in a variety of fluidic situations, with potential applications in drug delivery, water pollutant clean-up, or the creation of new types of smart materials that change their properties on command.

“The essential new principles we discovered—how to make microscopic objects swim on command using simple materials that undergo when exposed to controllable energy sources—pave the way for applications that range from design of responsive fluids, controlled , and new classes of sensors, to name a few,” explained lead researcher Juan de Pablo.

Implantable bioelectronics and wearable sensors for kidney health and disease

Advances in biosensor technology have the potential to enable continuous, non-invasive monitoring of kidney health through wearable and implantable systems. Non-invasive microfluidic systems have demonstrated utility in the detection of kidney-relevant biomarkers in peripheral body fluids such as sweat, interstitial fluid, tears and saliva, whereas implantable systems permit the direct measurement of biophysical tissue properties including tissue oxygenation, perfusion and temperature.

Heavy Drinkers Face Higher Risk of Brain Lesions And Alzheimer’s Markers

Alcohol is notoriously bad for health, and a recent study might add “long-term effects on brain health” to the growing list of ways drinking can cause harm.

The research, led by scientists at the University of São Paulo in Brazil, investigated the impact of regular drinking by examining brain autopsy data from 1,781 individuals, correlating findings with their reported drinking habits.

After adjusting for sociodemographic and clinical variables, like smoking and physical activity, the team found that the heaviest drinkers had a 133 percent higher risk of developing vascular brain lesions compared to non-drinkers.

High-performance memory devices can dissolve in water to address e-waste problem

The use of electronics in various forms is on the rise, from wearable devices like smartwatches to implantable devices like body-implanted sensors, skin-worn smart patches, and disposable monitoring devices. These devices, which are inevitably discarded after use, contribute to the growing problem of electronic waste (e-waste), a significant environmental concern.

The Korea Institute of Science and Technology (KIST) has announced that a joint research team, led by Dr. Sangho Cho of the Center for Extreme Materials Research and Dr. Yongho Joo of the Center for Functional Composite Materials Research, has developed a that offers high-performance data storage while completely degrading within days when immersed in water. The research is published in the journal Angewandte Chemie International Edition.

The material is biocompatible and stable enough for implantation in the human body, and the onset of degradation can be controlled by adjusting the thickness and the composition of the protective layer. Once this protective layer dissolves, the material degrades naturally in water within approximately three days, without leaving any residue.