A different kind of human cell division could improve our understanding of cancer and help us grow specific tissues
Category: biotech/medical – Page 4
New research from the University of Bristol has uncovered striking links between immune system proteins and neuropsychiatric conditions, including schizophrenia, depression, and Alzheimer’s disease. By analyzing large genetic datasets using Mendelian randomisation, scientists identified 29 immune-related proteins potentially playing a causal role in these disorders.
The findings suggest that mental health conditions may not be isolated to the brain but involve the entire body, potentially reshaping future treatment strategies. This video explores how inflammation and immune pathways could be the next frontier in neuropsychiatric care.
#mentalhealth #immunesystem #neuroscience #health #psychology #depression
University of Missouri researchers developed the tiny clay-based materials that can be customized for a range of analytical, commercial and medical applications.
Imagine tiny LEGO pieces that automatically snap together to form a strong, flat sheet. Then, scientists add special chemical “hooks” to these sheets to attach glowing molecules called fluorophores.
Associate Professor Gary Baker, Piyuni Ishtaweera, Ph.D., and their team have created these tiny, clay-based materials—called fluorescent polyionic nanoclays. They can be customized for many uses, including advancing energy and sensor technology, improving medical treatments and protecting the environment.
In patients with T2D who had been hospitalized for poorly controlled blood glucose, SGLT2 inhibitors nearly doubled the risk for falls, and combined use with GLP-1 RAs nearly tripled the risk.
Synthetic biology explained, future of synthetic biology, what is synthetic biology, creating life from DNA, synthetic life creation, synthetic biology techn…
Drugs that eliminate wakefulness, molecules in cannabis and wearable devices that modulate brain activity could help those with the condition.
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Northwestern University engineers have developed a pacemaker so tiny that it can fit inside the tip of a syringe — and be non-invasively injected into the body.
Smaller than a single grain of rice, the pacemaker is paired with a small, soft, flexible, wireless, wearable device that mounts onto a patient’s chest to control pacing. When the wearable device detects an irregular heartbeat, it automatically shines a light pulse to activate the pacemaker. These short pulses— which penetrate through the patient’s skin, breastbone and muscles — control the pacing. #Repost
Although it can work with hearts of all sizes, the pacemaker is particularly well-suited to the tiny, fragile hearts of newborn babies with congenital heart defects.
Designed for patients who only need temporary pacing, the pacemaker simply dissolves after it’s no longer needed. All the pacemaker’s components are biocompatible, so they naturally dissolve into the body’s biofluids, bypassing the need for surgical extraction.
Four children have gained life-changing improvements in sight following treatment with a pioneering new genetic medicine through Moorfields Eye Hospital and UCL Institute of Ophthalmology.
The work was funded by the NIHR Research Professorship, Meira GTx and Moorfields Eye Charity.
The 4 children were born with a severe impairment to their sight due to a rare genetic deficiency that affects the ‘AIPL1’ gene. The defect causes the retinal cells to malfunction and die. Children affected are only able to distinguish between light and darkness. They are legally certified as blind from birth.
The new treatment is designed to enable the retinal cells to work better and to survive longer. The procedure, developed by UCL scientists, consists of injecting healthy copies of the gene into the retina through keyhole surgery. These copies are contained inside a harmless virus, so they can penetrate the retinal cells and replace the defective gene.
The condition is very rare, and the first children identified were from overseas. To mitigate any potential safety issues, the first 4 children received this novel therapy in only one eye.
The eye gene therapy was delivered via keyhole surgery at Great Ormond Street Hospital. The children were assessed in the NIHR Moorfields Clinical Research Facility, and the NIHR Moorfields Biomedical Research Centre provided infrastructure support for the research.
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In a large population-based cohort of individuals who underwent electron-beam CT, coronary artery calcium score was independently associated with incident lung cancer diagnosis but did not demonstrate potential to improve risk stratification in lung cancer screening.