Lifeboat Foundation: Safeguarding Humanity
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Category: biotech/medical – Page 2,743

Humanity will be lost

I did a new interview on #transhumanism for some journalism students at Germany’s Technical University of Dortmund. It’s in English:

Mechanical bodyparts are very common nowadays – a lot of humans have a hip replacement or a pacemaker. Technology helps saving our lives rather often. Some people want to take this a lot further – a philosophical and scientific movement called Transhumanism. Zoltan Istvan Gyurko is one of the most famous Transhumanists, he even ran for president in 2016. In this interview, he talks about his first experiences with Transhumanism, immortality and the future of humanity.

By Marie-Louise Timcke und Paul Klur

Why is Transhumanism important for our society nowadays?

Zoltan Istvan: Well, Transhumanism is perhaps the most important subject matter that we have actually existing in society at the moment. Because humankind has been moving forward very slowly developing science and technology. But in ways that haven’t really rudimentary changed the human being. But all of a sudden, since the invention of the microchip, humanity is changing dramatically because of data, because of the internet, because of computers, because of smartphones. And what we have seen is almost nothing compared to what we’re going to see over the next ten or twenty years. Transhumanism is the field that wants to use science and technology to modify the human being and realise this kind of digitization of the actual self. But most importantly, the next ten years are going to be completely disruptive to whatever we thought it meant to be human beings.

Forget ‘live fast, die young’ – do the opposite instead

So far, the only intervention that is known to increase lifespan in multiple species is caloric restriction (CR). Caloric restriction is known to increase lifespan in the majority of mouse strains tested[1]. The effects of CR have even been shown to influence how primates age and reduce the incidence of diabetes, cancer, cardiovascular disease, and brain atrophy[2].

Science has known about the effects of CR since the 1930s, when rat experiments first showed researchers this phenomenon[3]. However, despite the various health benefits of CR, how it delays aging has remained a mystery. A new study suggests that epigenetic drift may be the answer.

A Japanese doctor who studied longevity — and lived to 105 — reveals the key to living a long life

On July 18, 2017 Japan lost a national treasure. He was the 105-year-old Dr. Shigeaki Hinohara.

Dr. Hinohara made a lion’s contribution to healthcare in Japan, both as a practicing medical doctor and as a physician. He headed five foundations in addition to being the president of St Luke’s International Hospital in Tokyo. He was responsible for introducing Japan’s system of comprehensive annual medical check-ups, which have been credited with greatly contributing to the country’s longevity, reports the BBC.

Those are laudable achievements, but it is his longevity and the fact that he saw patients until a few months before his death that defies everything we have come to expect of old age.

Robert Shmookler Reis Joins the LEAF Advisory Board

We are very pleased to announce that Dr. Robert Shmookler Reis has joined the LEAF scientific advisory board. He studied at Harvard University (B.A.) and Sussex University (D.Phil.). He joined the University of Arkansas for Medical Sciences in 1980, where he holds the Udupa Chair of Gerontologic Research; he also serves as Affiliate Professor of Pathology at the Univ. of Washington in Seattle WA.

Dr. Robert Shmookler Reis is an expert in genetics whose work focuses on the molecular genetics of longevity and age-associated diseases and his team holds the world record for life extension in C. elegans (roundworms) making them live ten times their normal lifespan.

Closing in on cancer

THE numbers are stark. Cancer claimed the lives of 8.8m people in 2015; only heart disease caused more deaths. Around 40% of Americans will be told they have cancer during their lifetimes. It is now a bigger killer of Africans than malaria. But the statistics do not begin to capture the fear inspired by cancer’s silent and implacable cellular mutiny. Only Alzheimer’s exerts a similar grip on the imagination.

Confronted with this sort of enemy, people understandably focus on the potential for scientific breakthroughs that will deliver a cure. Their hope is not misplaced. Cancer has become more and more survivable over recent decades owing to a host of advances, from genetic sequencing to targeted therapies. The five-year survival rate for leukemia in America has almost doubled, from 34% in the mid-1970s to 63% in 2006-12. America is home to about 15.5m cancer survivors, a number that will grow to 20m in the next ten years. Developing countries have made big gains, too: in parts of Central and South America, survival rates for prostate and breast cancer have jumped by as much as a fifth in only a decade.

Walking DNA nanorobot could deliver a drug to a precise location in your body

DNA nanorobot cargo carrier (artist’s impression) (credit: Ella Maru Studio)

Caltech scientists have developed a “cargo sorting” DNA nanorobot programmed to autonomously “walk” around a surface, pick up certain molecules, and drop them off in designated locations.

The research is described in a paper in the Friday, September 15, 2017 issue of Science.

In China, Robot Dentists Are Implanting 3D Printed Teeth

Open wide, because the robots have eyes on your dental work. South China Morning Post reports that a robo-dentist has autonomously implanted two new, 3D-printed teeth into a woman’s mouth.

The procedure, which appears to have made use of a robot arm from Universal Robotics, was developed by a team from the Fourth Military Medical University and Beihang University. The hardware first orients itself with the patient’s head, and is then programmed with the procedure it needs to undertake. It does a dry run to check that it’s got everything right, before the patient is given an anesthetic and the robot gets drilling. The team says that the robot works to tolerances of less than 0.3 millimeters, and can detect and compensate for movements of the person’s head.

Don’t fancy the idea? Well, bear in mind that it’s hoped the robot will be able to make up for a shortfall in the number of practicing dentists in China, which often leads to unqualified practitioners performing questionable procedures.

Michio Kaku, Gregory Stack, And Yue Shao: Synthetic Human Embryos And Genetic Engineering [Opinion]

Michio Kaku and Gregory Scott discuss different aspects of genetic engineering in the video below. According to Kaku and Scott, parents will soon have different genetic engineering choices to make about their children. In addition, recent discoveries by Yue Shao have yielded a new classification of parentless synthetic human embryos.

With Yue Shao’s discovery, genetic engineers might be learning to grow synthetic human embryos from anonymous stem cells donated from IVF clinics. How far this genetic engineering technology goes remains to be seen.

Michio Kaku and Gregory Scott speak about the ethical concerns of genetic engineering in the Michio Kaku video below beginning at the 29-minute mark. However, Yue Shao’s statements to MIT about the accidental discovery of how to engineer synthetic human embryos out of stem cells raises more ethical concerns.