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The so-called “year without a summer,” 1816, was bleak, if not strangely gothic. Mount Tambora in Indonesia had erupted the year before, pitching volcanic ash into the atmosphere and obscuring the sun. Torrential rains pressed deep into the year, resulting in global crop failures. The birds quieted down by midday, as darkness descended, and for days at a time, a group of writers huddled by candlelight in a rented mansion on Lake Geneva. The dashing 23-year-old poet Percy Shelley and his 18-year-old companion, Mary, who had already taken to calling herself “Mrs. Shelley,” traveled to the lake to spend the summer with the poet Lord Byron. On the night of June 15, 1816, they read ghost stories aloud. And then, Byron suggested they each try their hand to write one.

Mary Shelley would write her stunning exegesis Frankenstein, or The Modern Prometheus in just under 11 months. She set forth to write a penny dreadful but instead wrote a stinging commentary on the times that came to her in a flash, a waking dream. A collision of forces discharged in her writing, and she produced something more than a ghost story—a “book of ideas.”

A scientist sets out to create a more perfect entity, only to have it backfire as the thing he creates gets out of control.

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The Life Extension Advocacy Foundation, in collaboration with Singularity University Moscow Chapter and consulting group Deloitte, is hosting in Moscow an expert discussion on how to inform society about the potential and the advancement of gerontology and preventive medicine.


Life Extension Advocacy Foundation, in collaboration with Singularity University Moscow Chapter and consulting group Deloitte, are hosting in Moscow an expert discussion on how to inform society about the potential and the advancement of gerontology and preventive medicine. These experts believe that attracting people’s attention to the capabilities of medical technologies to prevent aging might help extend the healthy period of life and significantly decrease morbidity from age-related diseases.

The panel discussion “6 ways to talk to people about ending aging” will bring together famous futurists, scientists, science popularizers and public figures who foster the dissemination of the idea to prevent aging in Russia and other countries.

Jose Luis Cordeiro, fellow of the World Academy of Art and Science (WAAS), director of life extension advocacy organization Humanity Plus.

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In recent articles, we have talked about the potential of the immune system to help repair tissue, including for peripheral nerve damage, Atherosclerosis, and Parkinson’s. Immune cells not only fight infection; as this new study shows, they also help the nervous system remove debris, paving the way for nerve regeneration following injury.

While previous studies suggested that nerve cell damage repair was conducted by other immune cell types, such as macrophages, researchers from Case Western Reserve University School of Medicine have shown that neutrophils also play a role.

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Dr. Aubrey De Grey is a biomedical gerontologist and the Chief Science Officer at SENS Research Foundation, a biomedical charity that funds research dedicated to combating aging. His research interests encompass the characterization of all the accumulating and eventually pathogenic molecular and cellular side-effects of metabolism (“damage”) that constitute mammalian aging, and the design of interventions to repair and/or obviate that damage. In line with his research, De Grey gave a talk at The Aspen Abu Dhabi Ideas Festival focusing on “Rejuvenating Biotechnology: Why age may soon cease to mean aging”.

In March 2017, the Aspen Abu Dhabi Ideas Forum welcomed some of the brightest and most interesting minds from the UAE and around the world to discuss four of the most important moonshot challenges facing our planet. The event was inspired by the world-famous Aspen Ideas Festival that has been taking place in Colorado since 2005, as a place for scientists, artists, politicians, business leaders, historians and educators to discuss some of the most fascinating ideas of our time. The 2017 Aspen Abu Dhabi Ideas Forum topics included: “System Shock: Calming the ‘politics of anger’”, “Beyond GDP: Targeting ‘all-in’ human welfare”, “Health: Extending the healthy human lifespan” and “Space: Living Sustainably beyond Earth”.

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Over just a few short years the CRISPR gene-editing technique has revolutionized science, affecting everything from medicine to agriculture. Two new breakthrough studies have just been published describing dual methods that make the process more precise and efficient paving the way for scientists to safely alter DNA mutations that cause thousands of different human diseases.

CRISPR is conventionally a cut-and-paste tool allowing scientists to chop out unwanted strands of DNA and insert new genes, but a large volume of human diseases are caused by a single point mutation somewhere in a person’s DNA. Up until now scientists have not been able to simply and directly erase or rewrite these single mutations in living human cells.

Our human genome consists of 3 billion base pairs made up of chemical units referred to by the letters A, C, G and There are 50,000 known genetic mutations that are linked to disease in humans and 32,000 of these are single point mutations. Half of those single point mutations have been identified as a G-C pair that has mutated into an A-T pair.

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