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Researchers 3D Print Functional Components of Human Heart

Go modular or even get an upgrade:


A team of researchers from Carnegie Mellon University just 3D printed functional components of the human heart — including small blood vessels and large beating ventricles.

“We now have the ability to build constructs that recapitulate key structural, mechanical, and biological properties of native tissues,” said Adam Feinberg, a professor at Carnegie Mellon and the co-founder of 3D printing company FluidForm, which built the tech the team used, in a statement.

Lub Dub

Printing tissues capable of functioning like the real thing is particularly challenging. Complex shapes have to be supported as they’re being printed or otherwise they begin to sag. The team solved this issue, according to a paper published in the journal Science today, by printing scaffolds from a temporary support gel.

Secretary Perry Stands Up Office for Artificial Intelligence and Technology

WASHINGTON, D.C.-Today, U.S. Secretary of Energy Rick Perry announced the establishment of the DOE Artificial Intelligence and Technology Office (AITO). The Secretary has established the office to serve as the coordinating hub for the work being done across the DOE enterprise in Artificial Intelligence. This action has been taken as part of the President’s call for a national AI strategy to ensure AI technologies are developed to positively impact the lives of Americans.

DOE-fueled AI is already being used to strengthen our national security and cybersecurity, improve grid resilience, increase environmental sustainability, enable smarter cities, improve water resource management, as well as speed the discovery of new materials and compounds, and further the understanding, prediction, and treatment of disease. DOE’s National Labs are home to four of the top ten fastest supercomputers in the world, and we’re currently building three next-generation, exascale machines, which will be even faster and more AI-capable computers.

“The world is in the midst of the Golden Age of AI, and DOE’s world class scientific and computing capabilities will be critical to securing America’s dominance in this field,” said Secretary Perry. “This new office housed within the Department of Energy will concentrate our existing efforts while also facilitating partnerships and access to federal data, models and high performance computing resources for America’s AI researchers. Its mission will be to elevate, accelerate and expand DOE’s transformative work to accelerate America’s progress in AI for years to come.”

AI Network Can Tell Age, Gender From Standard ECG

NEW YORK (Reuters Health) — A convolutional neural network trained through deep learning can accurately predict a person’s age and gender using only standard 12-lead ECG signals, researchers report.

“Our standard diagnostic tools may have far more information behind them than we’ve come to expect throughout standard approaches to diagnostic interpretation,” said Dr. Suraj Kapa from Mayo Clinic College of Medicine, in Rochester, Minnesota.

“Between this study and other prior studies showing that we can predict likelihood of having atrial fibrillation from a normal sinus ECG or the presence of a low ejection fraction, AI-enabled ECG analysis may offer new, rapid, and cost-effective insights into human health well beyond what we could have anticipated in the last two centuries since the ECG was first developed,” he told Reuters Health by email.

James Strole: Advocacy, Education, Awareness About Radical Life Extension

Ira Pastor, ideaXme longevity and aging ambassador and founder of Bioquark, interviews James Strole, Co-Founder and Co-Director of People Unlimited and Director of the Coalition For Radical Life Extension.

Ira Pastor Comments:

On the last several shows we have spent time on different hierarchical levels the biologic-architecture of the life, disease and aging process. We’ve spent some time talking about the genome, the microbiome, tissue engineering, systems biology, quantum biology, organism hydrodynamics, biosemiotics, and chronobiology.

As exciting and promising as all of these research paths are, at the end of the day, in order for them to yield what many of us are looking for, radically extended healthspans and lifespans, and for them to be translated at scale, that is: approved by regulators, marketed by large pharma and CPG companies, and prescribed by a millions of clinicians (especially as the target market is all 7+ billion inhabitants of the planet), there needs to be an appropriate system of advocacy, education, awareness, and networking built around them to spread the word of the possibilities and the beautiful future that they can bring.

For today’s guest, I could think of no one better to come talk with us about this topic and take us into the future, than James Strole.

James is the Co-Founder and Co-Director of People Unlimited, an organization that’s involved in inspiring, educating, and connecting like minded people interested in achieving unlimited lifespans.

Individual response to flu vaccine influenced

A new study in healthy adults suggests that antibiotics may reduce the effectiveness of the flu vaccine.

The depletion of gut bacteria by antibiotics appears to leave the immune system less able to respond to new challenges, such as exposure to previously unencountered germs or vaccines, said Bali Pulendran, Ph.D., professor of pathology and of microbiology and immunology at the Stanford University School of Medicine.

“To our knowledge, this is the first demonstration of the effects of broad-spectrum antibiotics on the immune response in human—in this case, our response to vaccination—directly induced through the disturbance of our gut bacteria,” he said.

Study Results Suggest Human Aging Can Be Reversed

A small clinical trial, which was conducted by a team of researchers led by Dr. Greg Fahy, has shown for the first time in humans that reversing biological age may be possible.

The results of TRIIM are in

The researchers spent a year running the Thymus Regeneration, Immunorestoration, and Insulin Mitigation (TRIIM) trial, which included 9 volunteers aged between 51 and 65. The trial was aimed at testing if a growth hormone and drug combination could be used safely in humans to restore thymic function lost due to aging [1].

James Strole — Director of the Coalition for Radical Life Extension / Producer of RAADfest — ideaXme Show — Ira Pastor

Mathematician Wins $3 Million Breakthrough Prize for ‘Magic Wand Theorem’

Alex Eskin, a mathematician at the University of Chicago, has won the $3 million 2019 Breakthrough Prize in Mathematics.

The Breakthrough Prizes were founded in 2013 by a group of tech billionaires (as well as multihundred millionaire Anne Wojcicki, co-founder and CEO of genomics and biotech company 23andMe). The prizes are awarded each year to researchers in mathematics, fundamental physics and the life sciences. Past winners decide who will win in each category.

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