Lifeboat Foundation

A research team in the US has created a software that can quickly identify the information in cancer reports that would not only save time and work-hours but also reveal overlooked avenues in cancer research.

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Much of the cancer-related data is drawn from electronic, text-based clinical reports that must be manually curated — a time-intensive process — before it can be used in research.

A collaborative effort involving Auburn University, Gen9 and Autodesk has developed a synthetic viral genome for bone cancer research and one which may prove revolutionary in the battle against cancer overall.

The sCAV2 virus, which is the longest functional virus created in oncology research, targets and destroys selected tumor cells while not impacting healthy cells, notes an announcement.

“This could change the way we fight cancer. It is that revolutionary,” states Dr. Bruce Smith, a professor in the department of pathobiology and director of the Auburn University Research Initiative in Cancer, in the announcement. “Our concept is taking personalized medicine to precision medicine. The technology to create a new virus by synthesizing it is a huge leap, but the ability to then make a customized virus tailored to the specific needs of each patient will be transformative.”

Continue reading “Synthetic virus may drive personalized medicine into precision medicine” »

A new avenue of research opens up for cancer and potential therapies.

A new study led by scientists at The Scripps Research Institute (TSRI) suggests there may be a way to limit tumor growth by targeting immune system cells called macrophages.

The research reveals that macrophages can “drill” through tumors to create new vessel-like structures for delivering oxygen and nutrients as tumors grow.

Continue reading “Immune cells may facilitate tumor growth” »

More commentary about the Steve Aoki Party for Science and the Aoki Foundation.

Music business entrepreneur Steve Aoki has been a supporter of the SENS rejuvenation research programs for a while now. I’m always pleased to see successful people being vocal about their support for SENS, putting it front and center when talking to their audiences. Placing this important scientific work — as well as the prospects for near future therapies, and the need for philanthropic funding — in front of a bigger audience is a vital to the continued growth of our community and continued progress towards the medical control of aging. We need to reach out to entirely new networks of people, those who would never seek out the longevity science community on their own, as among their numbers are many who will be turn out to be interested, pleasantly surprised, and enthusiastic. Today, I’d wager, a large fraction of those people who will go on to be significant advocates and philanthropic donors of the late 2020s have no idea that we even exist, or that bringing an end to age-related disease, frailty, and suffering is possible outside the realm of science fiction.

Bootstrapping a cause never stops being hard. It was hard when small groups were striving to raise a few thousand dollars for SENS advocacy here and there, when having regular research programs and a million dollar fund looked to be an impossible distance away. It is hard today, when the SENS Research Foundation is trying to make the leap from a few million dollars in yearly research budgets to something ten times that size. Building greater public awareness and enthusiasm for the medical science of human rejuvenation is a very necessary part of that work. The sooner we collectively manage to change the zeitgeist to one in which charitable support for rejuvenation research is just as normal and lauded as support for cancer research, the better off we all are, and the more money that can be raised for scientific projects. So thanks are due to Steve Aoki for stepping up to the plate and taking a swing at this.

Continue reading “The Work of the Aoki Foundation to Support SENS Rejuvenation Research” »

WeaRobot wants to democratize robotic exoskeletons. They want to make modular exoskeletons, so that is more affordable. The exoskeleton can boost the mobility joint by joint. Just supporting the movement of one knee or one elbow or assembling all modules for a full body exoskeleton. This is targeted at enhancing mobility and function for the growing elderly population.

WeaRobot is breaking apart robotic exoskeletons to make them more affordable and adaptable.

Continue reading “Modular Exoskeletons” »

Bacteria are among the oldest life forms on Earth and exist nearly everywhere; in the soil, water, deep in the earth’s crust and in our own bodies. Actually, there are at least as many bacterial cells in the human body as human cells.

Bacteria tend to get a bad rap, but now, armed with new research on the bacterial world (or microbiome) in our bodies, we are starting to understand how important a role microorganisms play in our health (good as well as bad).

And beyond merely understanding the relationship between our bodies and the microorganisms inhabiting it, we’re on the cusp of significantly altering that relationship.

Continue reading “Pill Packing 100 Billion Designer Bacteria Could Be Tested Next Year” »

In Brief:

• Using a system of electrodes, transmitters, receivers, scientists were able to restore leg function in a primate, completely bypassing damaged nerves.
• While this remarkable feat may be decades away from human use, it is a promising development for the hundreds of thousands of people in the U.S. with spinal cord injuries

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ADELPHI, Md. — A U.S. Army Research Laboratory biotechnology scientist recently published an editorial article on the future directions of synthetic biology research to meet critical Army needs in the Synthetic Biology edition of the Journal of the American Chemical Society.

In the publication, Dr. Bryn Adams, who works in ARL’s Bio-Technology Branch, highlights examples of robust, tractable bacterial species that can meet the demands of tomorrow’s state-of-the-art in synthetic biology.

“ACS Synthetic Biology is the premier synthetic biology journal in the world, with a wide readership of biologists, chemists, physicists, engineers and computer programmers,” Adams said. “A publication in this journal allows me to challenge the leaders in the field to meet a Department of Defense specific need — the need for new synthetic biology chassis organisms, or host cell, and toolkits to build complex circuits in them.”

Continue reading “Synthetic biology research may enable future capabilities for Soldiers” »

Tomi Laurila’s research topic has many quirky names.

‘Nanodiamond, nanohorn, nano-onion…’ lists off the Aalto University Professor, recounting the many nano-shapes of carbon. Laurila is using these shapes to build new materials: tiny sensors, only a few hundred nanometres across, that can achieve great things due to their special characteristics.

Tl.pngFor one, the sensors can be used to enhance the treatment of neurological conditions. That is why Laurila, University of Helsinki Professor Tomi Taira and experts from HUS (the Hospital District of Helsinki and Uusimaa) are looking for ways to use the sensors for taking electrochemical measurements of biomolecules. Biomolecules are e.g. neurotransmitters such as glutamate, dopamine and opioids, which are used by nerve cells to communicate with each other.