Biotech/medical – Lifeboat News: The Blog

Apr 16
2019

Study finds diabetes drug may prevent, slow kidney disease

A drug that’s used to help control blood sugar in people with diabetes has now been shown to help prevent or slow kidney disease, which causes millions of deaths each year and requires hundreds of thousands of people to use dialysis to stay alive.

Doctors say it’s hard to overstate the importance of this study, and what it means for curbing this problem, which is growing because of the obesity epidemic.

The study tested Janssen Pharmaceuticals’ drug Invokana. Results were discussed Sunday at a medical meeting in Australia and published by the New England Journal of Medicine.

Apr 16
2019

Liquid Blood Extracted From 42,000-Year-Old Foal Found Frozen in Siberia

Scientists in the Yakutsk region of Siberia have managed to extract samples of liquid blood from a 42,000-year-old foal that was found embedded in permafrost back in 2018. The scientists are hoping to collect viable cells for the purpose of cloning the extinct species of horse.

The male foal was discovered in the Batagaika depression on August 11, 2018. Permafrost left the remains in remarkably good shape, raising hopes that its cells could be extracted. The specimen is thought to belong to an extinct species of horse known as Lenskaya breed (also known as the Lena horse), as the Siberian Times reported last year.

Apr 16
2019

Cheap, portable scanners could transform brain imaging. But how will scientists deliver the data?

Q&A with neuroethicist Francis Shen and MRI developer Michael Garwood.

Apr 16
2019

First U.S. Patients Treated With CRISPR As Human Gene-Editing Trials Get Underway

CRISPR Research Moves Out Of Labs And Into Clinics Around The World : Shots — Health News This could be a crucial year for the powerful gene-editing technique CRISPR as researchers start testing it in patients to treat diseases such as cancer, blindness and sickle cell disease.

Apr 16
2019

Extending Human Longevity With Regenerative Medicine

Understandably, the FDA raised concerns about the practice of parabiosis because to date, there is a marked lack of clinical data to support the treatment’s effectiveness.

Elevian

On the other end of the reputability spectrum is a startup called Elevian, spun out of Harvard University. Elevian is approaching longevity with a careful, scientifically validated strategy. (Full Disclosure: I am both an advisor to and investor in Elevian.)

Apr 16
2019

An Interview with Dr. Joan Mannick of resTORbio

A number of companies are studying and commercializing rapamycin and rapalogs, including resTORbio, a Boston-based company. Tam Hunt got in touch with Dr. Joan Mannick from the company to find out more about this promising anti-aging therapeutic.

Blagoskonny ([3], [4]) has suggested that rapamycin and rapalogs are effective anti-aging therapies today for humans as well as other animals because they arrest “quasi-programmed hypertrophy.” What are your thoughts on Blagoskonny’s theory?

I think Blagoskonny’s theory is very interesting. mTOR stimulates cell growth, and there is data that mTOR becomes hyperactive in some aging tissues. This may explain why TORC1 inhibitors have benefit in aging-related diseases.

Apr 16
2019

A Jeff Bezos-backed startup just inked a deal with $84 billion biotech Gilead to make drugs for a troubling and increasingly common disease

Insitro and Gilead are teaming up to create drugs to treat a liver disease affecting millions. The startup is backed by Jeff Bezos, Andreessen Horowitz, and GV.

Apr 16
2019

Drug-resistant bugs discovered in animal hospital prompts health warning

Pets in a British animal hospital have been found to be harbouring potentially lethal drug-resistant bugs that could be transferred to owners.

Tests by Public Health England (PHE) revealed three cats a dog were colonised by bacteria able to fend off Linezolid, a “last-resort” antibiotic used to treat superbugs such as MRSA (methicillin-resistant Staphylococcus aureus).

No staff or owners are known to have been taken ill as a result, however the agency last night warned veterinary surgeries to enforce proper cleaning practices after this first discovery of its kind.

Apr 16
2019

Drug-resistant fungus is sprouting worldwide, and it has health researchers worried

Drug-resistant fungi are appearing around the globe, and some are known to cause illness in humans.

Apr 16
2019

DNA reveals origin of Stonehenge builders

The ancestors of the people who built Stonehenge travelled west across the Mediterranean before reaching Britain, a study has shown.

Researchers in London compared DNA extracted from Neolithic human remains found in Britain with that of people alive at the same time in Europe.

The Neolithic inhabitants appear to have travelled from Anatolia (modern Turkey) to Iberia before winding their way north.