Lifeboat Foundation

An interesting new study has demonstrated a method to reprogram specific T cells. Much like researchers have been experimenting recently with macrophages and making them change into an anti-inflammatory rather than a proinflammatory type, the team here has achieved similar results with T cells.

As we age the immune system becomes dysfunctional, either due to immune cells become overactive and creating too much inflammation or by cells that suppress the immune system such as senescent cells that inhibit cell function.

A dysfunctional immune system leaves us vulnerable to diseases and chronic levels of inflammation from excessive immune responses prevent tissue regeneration and wound healing. The researchers here have discovered how to target pro-inflammatory T cells that increase the immune response and inflammation and change them into anti-inflammatory cells that suppress the immune response, and vice versa.

Obesity affects more than 600 million adults and around 41 million children under the age of 5 according to the Center for Disease Control and Prevention. Researchers may have found a way to halt the development of both type 2 diabetes and obesity in humans using a recently discovered protein.

In step forward for Elon Musk’s neural lace and transhumanists everywhere, a new paper published this month by researchers at Harvard University reports on the successful implantation of an electronic neuromorphic mesh in the brains of mice without triggering an immune response.

Neuroprostheses show promise in the treatment of Alzheimer’s Disease, Parkinson’s Disease, epilepsy, traumatic brain injury and for the creation of brain-machine interfaces such as the neural lace, but a major stumbling block for researchers has been the propensity of these implants to induce an immune response, inflammation and scaring in the brain, severely limiting their potential use.

Continue reading “Study Shows Injectable Electronic Neural Lace Melds With Neurons Without Causing Immune Response” »

Ready and waiting at an arms reach from the government, the Research and Development Corporation (RAND) has helped the U.S. think through some of the toughest scientific and regulatory challenges since the 1940s. This year, the think tank is opening its first office in the San Francisco Bay Area. Its positioning itself to weigh in on some of Silicon Valleys largest research projects, like autonomous vehicles, drones, AI, cybersecurity and telemedicine.

But unlike the RAND of the past, this new version embodies the scrappiness of startup culture. Formally based out of a WeWork space, office director Nidhi Kalra and the rest of her SF team largely work decentralized from homes and coffee shops around the Bay Area.

The team of a dozen researchers is here to study the development of new technologies and the way in which state and local authorities are working side-by-side with startups to keep everyone safe without sundering innovation.

Continue reading “The Wizards of Armageddon set up shop in Silicon Valley” »

“Worse than death:” The far-future dystopia of genome hacking.

This scientist’s thought experiment will give you nightmares.

Groundbreaking project corrects faulty DNA linked to fatal heart condition and raises hopes for parents who risk passing on genetic diseases.

SGI-DNA has launched the world’s first DNA printer. The BioXp 3200 system is an automated personal genomic workstation that builds and clones DNA fragments virtually hands-free. Source: SGI-DNA. A Synthetic Genomics Inc. Company.

Analysis connects Greeks to the famed Mycenaeans and Minoans.

Two researchers are impressed with a pioneering study showing that it may be both safe and effective to edit out diseases in human embryos.