This week, UK-based futurologist Ian Pearson announced humanity will achieve immortality by the year 2050. Is he right?
According to the former rocket scientist and IT engineer – who claims to have an 85 percent success rate “when looking 10–15 years ahead” – recent advances in biomedical and computing technology will inevitably lead to victory over death via one of three means:
Elizabeth Parris, the CEO of Bioviva USA Inc, has become the very first human being to successfully, from a biological standpoint, reverse the age of her white blood cells, thanks to her own company’s experimental therapies. Bioviva utilizes intramural and extramural peer-reviewed research to create therapies for age-related diseases (Parkinson’s, Alzheimer’s, cancer, heart-disease), and now, they have reversed 20 years of ‘telomere shortening’ in a human for the first time.
Telomeres are short segments of DNA that cap the ends of every chromosome and act as a protective feature against wear and tear, which occurs naturally as the human body ages. As we age, these telomeres become shorter and shorter as our cells continue to divide more and more. Eventually they become too short to protect the chromosome, which is what causes our cells to malfunction and age related diseases to start setting in.
In September of last year, the 44 year old volunteered to partake in two of her own company’s experimental gene therapies; one intended to battle stem cell depletion, which happens when we age and leads to various age related diseases, and the other intended to protect against loss of muscle mass with age.
“I think I’m crazy enough to do it,” he told Nature.
Rebrikov plans to target CCR5, the same gene as He, which could theoretically make the babies immune to HIV. But experts say the risks and unknowns — including the possibility of premature death — vastly outweigh any potential benefits.
“The technology is not ready,” CRISPR-Cas9 co-inventor Jennifer Doudna told Nature of Rebrikov’s plans. “It is not surprising, but it is very disappointing and unsettling.”
Who are you really talking to?
AT&T Labs will begin selling speech software it says is so good at reproducing sounds, inflections and intonations of human voice, that it can recreate voices and even bring those of long-dead celebrities back to life; Natural Voices software, which turns printed text into synthesized speech, makes it possible for company to use recording of person’s voice to utter things person never actually said; utterances still contain few robotic tones and unnatural inflections, leading competitors to question whether it is substantial step up from existing products; tests suggest it may be first text-to-speech software to raise specter of voice cloning, replicating person’s voice so perfectly that human ear cannot tell difference; photo (M)
As we age, the reduced turnover of our cells means we can lose control over how our skin ages. Epidermal stem cells needed to create healthy new skin are significantly reduced and function less efficiently. A discovery based on promising plant stem cell research may allow you to regain control.
Scientists have found that a novel extract derived from the stem cells of a rare apple tree cultivated for its extraordinary longevity shows tremendous ability to rejuvenate aging skin. By stimulating aging skin stem cells, this plant extract has been shown to lessen the appearance of unsightly wrinkles. Clinical trials show that this unique formulation increases the longevity of skin cells, resulting in skin that has a more youthful and radiant appearance.
A new publication highlights how the complex interaction of NAD+ and cellular senescence pathways may complicate proposed anti-aging therapies that boost NAD+ using precursors.
What are epigenetic alterations?
One of the proposed reasons we age is the changes to gene expression that our cells experience as we get older; these are commonly called epigenetic alterations. These alterations harm the fundamental functions of our cells and can increase the risk of cancer and other age-related diseases.
