Lifeboat Foundation

Researchers from North Carolina State University and Elon University have developed a technique that allows them to remotely control the movement of soft robots, lock them into position for as long as needed and later reconfigure the robots into new shapes. The technique relies on light and magnetic fields.

“We’re particularly excited about the reconfigurability,” says Joe Tracy, a professor of materials science and engineering at NC State and corresponding author of a paper on the work. “By engineering the properties of the material, we can control the soft robot’s movement remotely; we can get it to hold a given shape; we can then return the robot to its original shape or further modify its movement; and we can do this repeatedly. All of those things are valuable, in terms of this technology’s utility in biomedical or aerospace applications.”

For this work, the researchers used soft robots made of a polymer embedded with magnetic iron microparticles. Under normal conditions, the material is relatively stiff and holds its shape. However, researchers can heat up the material using light from a light-emitting diode (LED), which makes the polymer pliable. Once pliable, researchers demonstrated that they could control the shape of the robot remotely by applying a magnetic field. After forming the desired shape, researchers could remove the LED light, allowing the robot to resume its original stiffness—effectively locking the shape in place.

Over 4000 patients in the United States alone are waiting for a heart transplant, while millions of others worldwide need hearts but are ineligible for the waitlist. The need for replacement organs is immense, and new approaches are needed to engineer artificial organs that are capable of repairing, supplementing, or replacing long-term organ function.

A team of researchers from Carnegie Mellon University has published a paper in Science that details a new technique allowing anyone to 3D bioprint tissue scaffolds out of collagen, the major structural protein in the human body. This first-of-its-kind method brings the field of tissue engineering one step closer to being able to 3D print a full-sized, adult human heart.

The technique, known as Freeform Reversible Embedding of Suspended Hydrogels (FRESH), has allowed the researchers to overcome many challenges associated with existing 3D bioprinting methods, and to achieve unprecedented resolution and fidelity using soft and living materials.

Continue reading “3D printing the human heart” »

Shift Bioscience is a company aiming to solve the problem of mitochondrial dysfunction, one of the hallmarks of aging, by repairing the aging mitochondria in our cells so that they work as if they were younger.

Mitochondrial dysfunction is at the heart of aging

The mitochondria are often called the powerhouses of cells, and they convert the food we eat into usable energy in the form of a chemical called adenosine triphosphate (ATP). ATP supplies energy for many cellular processes, such as muscle contraction, nerve impulse propagation, and protein synthesis. ATP is found in all forms of life and is often referred to as the “molecular unit of currency” of intracellular energy transfer.

In a paper published in the July 31 issue of Science Translational Medicine, researchers at Fred Hutchinson Cancer Research Center used CRISPR-Cas9 to edit long-lived blood stem cells to reverse the clinical symptoms observed with several blood disorders, including sickle cell disease and beta-thalassemia.

It’s the first time that scientists have specifically edited the genetic makeup of a specialized subset of adult blood stem cells that are the source of all cells in the blood and immune system.

The proof-of-principle study suggests that efficient modification of targeted stem cells could reduce the costs of gene-editing treatments for blood disorders and other diseases while decreasing the risks of unwanted effects that can occur with a less discriminating approach.

A solid clarification article in a major newspaper where I point out that the transhumanism movement is vastly different than how Epstein interpreted in in 2011. Transhumanists need to speak up about what their vision of transhumanism is so others and media know what it really is about.

The revelation that convicted sex offender Jeffrey Epstein planned to impregnate 20 women with his sperm in a “DNA seeding” centre left the world feeling sick. But for patrons of a small, but growing, political movement it caused utter chaos.

“This is the largest media coverage we have ever experienced,” says Zoltan Istvan, former presidential candidate and founder of the Transhumanist Party. “But this is the worst type of coverage. Lots of damage control is being done right now.”

Continue reading “The truth about Jeffrey Epstein and his fascination with transhumanism” »

Arch Intern Med. 1997 Feb 10;157:281–5.

Growing numbers of patients suffering from many symptoms believe that they have a condition called multiple chemical sensitivity syndrome (MCSS). It has been suggested that this syndrome can be triggered by exposure to any of a large and usually incompletely defined number of natural and synthetic chemical substances. Major medical organizations, including the National Research Council and the American Medical Association, have not recognized MCSS as a clinical syndrome because of a lack of valid, well-controlled studies defining it and establishing pathogenesis or origin. Lately, some have proposed that many patients with MCSS suffer from hereditary coproporphyria. However, this purported association is based chiefly on results from a single reference laboratory of a fundamentally flawed assay for erythrocyte coproporphyrinogen oxidase.

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Today would have been the 99th birthday of Ms. Henrietta Lacks, a woman whose remarkable DNA led to countless cures, patents and discoveries:

But critics point out that all that promise could vanish if the rush to implement A.I. tramples patient privacy rights, overlooks biases and limitations, or fails to deploy services in a way that improves health outcomes for most people.

You could be forgiven for thinking that A.I. will soon replace human physicians based on headlines such as “The A.I. Doctor Will See You Now,” “Your Future Doctor May Not Be Human,” and “This A.I. Just Beat Human Doctors on a Clinical Exam.” But experts say the reality is more of a collaboration than an ousting: Patients could soon find their lives partly in the hands of A.I. services working alongside human clinicians.

Continue reading “Will Artificial Intelligence Improve Health Care for Everyone?” »

In 1948, physicist Leonard Eisenbud proposed a particular way of transmitting the waves to overcome this. But not until now have researchers made it happen.

By Michael Slezak.

It’s a call with no response. A new way of creating waves – whether of light, radio or sound – that don’t echo promises to improve everything from your Wi-Fi signal to medical imaging to shining lasers through space.

Continue reading “Echoless light could help send signals through walls and skin” »