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Archive for the ‘biotech/medical’ category: Page 1871

Apr 30, 2019

CRISPR Trials on Humans Officially Begin in the US

Posted by in category: biotech/medical

CRISPR Trials on Humans officially begin in the US to Treat Cancer.

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Apr 30, 2019

Deadly box jellyfish antidote discovered using CRISPR genome editing

Posted by in category: biotech/medical

Researchers at the University of Sydney have discovered an antidote to the deadly sting delivered by the most venomous creature on earth—the Australian box jellyfish.

The Australian box jellyfish (Chironex fleckeri) has about 60 tentacles that can grow up to three metres long. Each tentacle has millions of microscopic hooks filled with .

Each box jellyfish carries enough venom to kill more than 60 humans.

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Apr 30, 2019

Scientists Plan to 3D Print Muscular Tissue on the Space Station

Posted by in categories: 3D printing, biotech/medical, space travel

The printed samples will help reveal how long-term space travel affects the human body.

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Apr 30, 2019

Finally, another effective drug for kids and teens with type 2 diabetes

Posted by in categories: biotech/medical, health

Results of a recently completed clinical trial of a potential drug to treat Type 2 diabetes in children were announced Sunday [April 28] at the Pediatric Academic Societies 2019 meeting in Baltimore, Md. The New England Journal of Medicine also published the findings. Study coauthor Jane Lynch, M.D., FAAP, professor of pediatrics at UT Health San Antonio, said the drug, liraglutide, in combination with an existing medication, metformin, showed robust effect in treating children studied in the Ellipse trial.

Currently only two drugs, metformin and insulin, are approved by the U.S. Food and Drug Administration for the treatment of Type 2 diabetes in children. By comparison, more than 30 drugs are approved to treat this form of diabetes in adults.

“We’ve not been able to get drugs approved for children beyond metformin and insulin,” Dr. Lynch said. “This adult diabetes medication was very effective in our trial of youth with Type 2 diabetes and was well tolerated. We urgently need other options for medical treatment of Type 2 diabetes in our youth under age 18. If approved, this drug would be a fantastic new option to complement oral metformin therapy as an alternative to insulin for our youth and adolescents with Type 2 diabetes.”

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Apr 30, 2019

DNA folds into a smart nanocapsule for drug delivery

Posted by in categories: biotech/medical, nanotechnology

Researchers from University of Jyväskylä and Aalto University in Finland have developed a customized DNA nanostructure that can perform a predefined task in human body-like conditions. To do so, the team built a capsule-like carrier that opens and closes according to the pH level of the surrounding solution. The nanocapsule can be loaded—or packed—with a variety of cargo, closed for delivery and opened again through a subtle pH increase.

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Apr 30, 2019

The April Journal Club will be discussing the recent paper from the Salk Institute

Posted by in categories: biotech/medical, life extension

The findings, published in the journal Nature Medicine, showcase a novel CRISPR/Cas9 genome-editing therapy that can suppress the accelerated aging observed in mice with Hutchinson-Gilford progeria syndrome. This treatment provides an important insight into the molecular pathways involved in accelerated aging, as well as how to reduce toxic proteins via gene therapy. The researchers hope to translate this therapy to humans to potentially provide a cure for progeria as well as possibly slowing down the aging process to delay the onset of age-related diseases in everyone.

Link to paper: https://www.nature.com/articles/s41591-019-0343-4

Abstract.

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Apr 30, 2019

Tony Oro: Stem cell therapies for incurable diseases

Posted by in category: biotech/medical

Illustration of human embryonic stem cells. | Science Source/Ian Cuming.

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Apr 30, 2019

NMN Improves Cognitive Function in Aged Mice

Posted by in categories: biotech/medical, life extension, neuroscience

Researchers have tested nicotinamide mononucleotide on aged mice to see if it can help reverse age-related cognitive decline by improving blood flow in the brain.

The brain is a hungry organ

Healthy brain function relies on efficient cerebral blood flow (CBF) to wash away harmful waste products for disposal and supply the brain with an adequate supply of oxygen and sufficient nutrients.

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Apr 29, 2019

Doctors used a drone to deliver a vital kidney transplant in historic flight

Posted by in categories: biotech/medical, drones

https://youtube.com/watch?v=RNYCCbCpAlM

Drones might be a favorite toy among adults with significant disposable income, but they’ve also proven to be incredibly useful as tools, and sometimes life-saving ones at that. The latest example of this growing trend comes to us from the University of Maryland Medical Center, where a medical drone delivered a kidney that was subsequently successfully transplanted into a patient.

The delivery, which was documented in a brief YouTube video published by UMMC, is just a small first step in a larger effort to enhance the delivery systems used for vital items like organs and other medical materials.

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Apr 29, 2019

‘Earth-shattering’: Drone delivers kidney for transplant over Baltimore

Posted by in categories: biotech/medical, drones, robotics/AI

https://youtube.com/watch?v=RNYCCbCpAlM

The drone delivery of a kidney recently used for an organ transplant in Baltimore is being characterized by the University of Maryland as a “pioneering breakthrough” advancement in human medicine and aviation technology.

“It’s huge. We knew from the very first time that we met with Dr. (Joseph) Scalea, and he suggested the idea of what he wanted to do — we knew it would be earth-shattering and life-changing, and it really has become that,” Matthew Scassero, director of the Unmanned Aircraft Systems Test Site at the University of Maryland, told WTOP.

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