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A 25-year quest for the Holy Grail of evolutionary biology

When I started my postdoc in 1998, I think it is safe to say that the Holy Grail (or maybe Rosetta Stone) for many evolutionary biologists was a concept called the Adaptive Landscape. The reason for such exalted status is that the adaptive landscape was then – and remains – the only formal quantitative way to predict and interpret an adaptive radiation of few organisms into many. I was heavily indoctrinated into this framework — as my postdoc was at UBC during precisely the time when Dolph Schluter was writing his now-classic book The Ecology of Adaptive Radiation.

Molecules in Motion: Advanced Spectroscopy Captures Molecular Dynamics in Real-Time

Researchers have developed a new method that uses attosecond core-level spectroscopy to capture molecular dynamics in real time.

The mechanisms behind chemical reactions are complex, involving many dynamic processes that affect both the electrons and the nuclei of the involved atoms. Frequently, the strongly coupled electron and nuclear dynamics trigger radiation-less relaxation processes known as conical intersections. These dynamics underpin many significant biological and chemical functions but are notoriously difficult to detect experimentally.

The challenge in studying these dynamics stems from the difficulty of tracing the nuclear and electronic motion simultaneously. Their dynamics are intertwined and occur on ultrafast timescales, which has made capturing the molecular dynamical evolution in real time a major challenge for both physicists and chemists in recent years.

The first example of cellular origami

“Geometry is destiny”

How a simple cell produces remarkably complex behavior, all without a nervous system.


Combining a deep curiosity and “recreational biology,” Stanford researchers have discovered how a simple cell produces remarkably complex behavior, all without a nervous system. It’s origami, they say.

Theory Predicts Collective States of Mobile Particles

Collections of mobile, interacting objects—flocks of birds, colonies of bacterial, or teams of robots—can sometimes behave like solid materials, executing organized rotations or gliding coherently in one direction. But why such systems display one kind of collective organization rather than another has remained unclear. Now researchers have developed a theory that can predict the pattern most likely to emerge under specific conditions [1]. The theory, they hope, may be of use in designing living and artificial materials that can autonomously adapt to their environment.

An “active material” is any system made up of interacting objects able to move under their own power, such as animals, cells, or robots. In so-called active solids, a subset of active materials, strong cohesion between neighboring elements makes the collective act somewhat like a solid. Examples include clusters of certain cell types and networks of robots with rigid connections.

Active solids can display several kinds of collective, organized motion, says Claudio Hernández-López, a PhD student at the École Normale Supérieure and Sorbonne University in France. For example, researchers have observed both coherent rotations and coherent translations in collections of microbes from the phylum Placozoa. Existing theories, however, fail to explain pattern selection—why, if several patterns are possible, does one pattern of behavior emerge rather than another?

This bold new theory of ‘quantum weirdness’ could rewrite the story of evolution

“… living systems evolve to exploit any aspect of physics that enables exploration of all possible ‘fitness landscapes’.”

Indeed!


In 1990, within the intellectual haven of Haverford College, I embarked on a transformative academic journey into biophysics – the captivating intersection of physics and biology.

It was during this time that I delved into the tantalising notion of quantum mechanics operating within living organisms.

Unbeknownst to me, this exploration would etch an enduring imprint on my scientific voyage, kindling a lifelong fascination with biophysics. Ultimately, I charted my research course in quantum cosmology, but the echoes of biophysics persisted.

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