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Category: biological – Page 3

How to See the Dead

Looking at the bench and readings, he concluded that the previous night’s firmware update had introduced a timing mismatch. The wires hadn’t burnt out, but the clock that told them when to fire had been off by a microsecond, so the expected voltage response never lined up. He suspected half the channels had dropped out, even though the hardware itself wasn’t damaged. Fifteen minutes and a simple firmware rollback later, and everything worked perfectly.

Now, Lyre and I swapped the saline for neuron cultures to check if the wires could trigger and record real biological data. While we confirmed, Aux fine-tuned his AI encoder and processed April’s data.

We were finally ready to test the integrated system, without yet risking its insertion into April’s brain. We built something we only half jokingly called a “phantom cortex,” a benchtop stand-in: a synthetic cortical sheet of cultured neurons on a chip designed to act as April’s visual cortex. On one side, we put a lab-grown retinal implant that carried live sensory input. On the other, Aux’s playback device pushed reconstructed memories. The phantom cortex’s visual field was rendered on a lab monitor so that we could assess the pattern projections. The phantom cortex rig buzzing faintly in the background, gelled neuron sheets twitching under the microscope with each ripple of charge.

Speaking more than one language may help the brain stay younger

Speaking more than one language can slow down the brain’s aging and lower risks linked to accelerated aging.

In a new study, researchers analyzed the Biobehavioral Age Gap (BAG) —a person’s biological age using health and lifestyle data, then compared it to their actual age—of over 80,000 participants aged 51–90 across 27 European countries. They found that people who speak only one language are twice as likely to experience accelerated aging compared to multilingual individuals.

Researchers suggest that the protective effect might arise from the constant ongoing mental effort required to manage more than one language. The findings of this study are published in Nature Aging.

Nature-inspired navigation system helps robots traverse complex environments without GPS

Robots could soon be able to autonomously complete search and rescue missions, inspections, complex maintenance operations and various other real-world tasks. To do this, however, they should be able to smoothly navigate unknown and complex environments without breaking down or getting stuck, which would require human intervention.

Most autonomous navigation systems rely on global positioning systems (GPS), which can provide information about where a robot is located within a map. In many environments, however, including caves, unstructured spaces and collapsed buildings, GPS systems either do not work or become unreliable.

Researchers at Beijing Institute of Technology recently developed a new nature-inspired system that could improve robot navigation in unstructured and complex environments, without relying on GPS technology. Their proposed framework— outlined in a paper set to be published in Cell Press and currently available on the SSRN preprint server—is inspired by three distinct biological navigation strategies observed in insects, birds and rodents.

Catalyst turns methane into bioactive compounds for the first time

Natural gas—one of the planet’s most abundant energy sources—is primarily composed of methane, ethane, and propane. While it is widely burned for energy, producing greenhouse gas emissions, scientists and industries have long sought ways to directly convert these hydrocarbons into valuable chemicals. However, their extreme stability and low reactivity have posed a formidable challenge, limiting their use as sustainable feedstocks for the chemical industry.

Now, a team led by Martín Fañanás at the Center for Research in Biological Chemistry and Molecular Materials (CiQUS) at the University of Santiago de Compostela has developed a groundbreaking method to transform methane and other components into versatile “building blocks” for synthesizing high-demand products, such as pharmaceuticals. Published in Science Advances, this advance represents a critical leap toward a more sustainable and circular chemical economy.

For the first time, the CiQUS team successfully synthesized a bioactive compound—dimestrol, a non-steroidal estrogen used in hormone therapy—directly from methane. This achievement demonstrates the potential of their methodology to create complex, high-value molecules from a simple, abundant, and low-cost raw material.

Want a younger brain? Learn another language

Speaking multiple languages could slow down brain ageing and help to prevent cognitive decline, a study of more than 80,000 people has found.

The work, published in Nature Aging on 10 November1, suggests that people who are multilingual are half as likely to show signs of accelerated biological ageing as are those who speak just one language.

“We wanted to address one of the most persistent gaps in ageing research, which is if multilingualism can actually delay ageing,” says study co-author Agustín Ibáñez, a neuroscientist at the Adolfo Ibáñez University in Santiago, Chile. Previous research in this area has suggested that speaking multiple languages can improve cognitive functions such memory and attention2, which boosts brain health as we get older. But many of these studies rely on small sample sizes and use unreliable methods of measuring ageing, which leads to results that are inconsistent and not generalizable.

“The effects of multilingualism on ageing have always been controversial, but I don’t think there has been a study of this scale before, which seems to demonstrate them quite decisively,” says Christos Pliatsikas, a cognitive neuroscientist at the University of Reading, UK. The paper’s results could “bring a step change to the field”, he adds.

They might also “encourage people to go out and try to learn a second language, or keep that second language active”, says Susan Teubner-Rhodes, a cognitive psychologist at Auburn University in Alabama.

Continue reading “Want a younger brain? Learn another language” | >

New enzyme network with competing peptides can make decisions based on external environment

The ability to respond to changing surroundings was once considered exclusive to complex living organisms. Then came computers, specially designed for stimulus–response tasks, which can take in signals from their environment and choose what to do next based on the instructions already written into them.

Scientists have long wanted to replicate this kind of behavior in . Life and computers both need many parts working in sync to make decisions, so expecting a handful of chemicals in a to do the same seemed quite far-fetched.

Not anymore. A team of researchers from the Netherlands and Australia has developed a novel chemical network where different peptides compete for enzymes—specifically proteases arranged in a network. This competition causes the to reorganize itself, forming an enzymatic network that adapts to the external environment.

Our research partners at UC San Diego have just announced revolutionary findings that challenge conventional understanding of human biology with the publication of their paper titled Neural and Molecular Changes During a Mind-Body Reconceptualization

Meditation, and Open Label Placebo Healing Intervention in the scientific journal Communications Biology.

Neural and Molecular Changes During a Mind-Body Reconceptualization, Meditation, and Open Label Placebo Healing Intervention

The landmark study demonstrates how intensive meditation can trigger the same profound brain activity previously documented only with psychedelic substances – while simultaneously activating measurable biological transformations throughout the entire body.

Scientists uncover what delayed Earth’s oxygen boom for a billion years

Billions of years ago, cyanobacteria began releasing oxygen through photosynthesis, but the atmosphere stayed oxygen-poor for ages. Researchers uncovered that trace compounds like nickel and urea may have delayed Earth’s oxygenation for millions of years. Experiments mimicking early Earth revealed how their concentrations controlled cyanobacterial growth, dictating when oxygen began to accumulate. As nickel declined and urea stabilized, photosynthetic life thrived, sparking the Great Oxidation Event. The findings could also guide the search for biosignatures on distant worlds.

The arrival of oxygen in Earth’s atmosphere marked a defining moment in the planet’s history, transforming it into a world capable of supporting complex life. This major shift, known as the Great Oxidation Event (GOE), took place approximately 2.1 to 2.4 billion years ago. However, oxygenic photosynthesis — produced by cyanobacteria — had likely evolved hundreds of millions of years before this event. Despite this early ability to generate oxygen, atmospheric levels remained low for a surprisingly long time. Scientists have long debated the cause of this delay, considering explanations such as volcanic emissions, chemical sinks, and biological interactions. Yet no single factor has fully explained why it took so long for oxygen to build up in Earth’s air.

To tackle this enduring question, researchers focused on an often overlooked element of early Earth chemistry: the role of trace compounds such as nickel and urea in cyanobacterial growth.

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