Lifeboat Foundation: Safeguarding Humanity
Toggle light / dark theme

Blog

Category: biological – Page 3

Going places: Muscle-inspired mechanism powers tiny autonomous insect robots

Science frequently draws inspiration from the natural world. After all, nature has had billions of years to perfect its systems and processes. Taking their cue from mollusk catch muscles, researchers have developed a low-voltage, muscle-like actuator that can help insect-scale soft robots to crawl, swim and jump autonomously in real-world settings. Their work solves a long-standing challenge in soft robotics: enabling tiny robots to move on their own without sacrificing power or precision.

Muscles are that work by contracting and relaxing to cause movement. Insect muscles are particularly good at this because they are incredibly powerful for their small size. Similarly, actuators are devices that convert mechanical energy into motion.

However, when it comes to robotics, creating tiny, powerful actuators that move with the same agility, precision and resilience as a biological has proved challenging. What’s more, the rigid motors in current robotic systems are difficult to scale down because they easily break.

Structured light manipulates material properties and reveals atomic changes in nanocrystals

Researchers with the schools of science and engineering at Rensselaer Polytechnic Institute (RPI) are exploring new ways to manipulate matter with light to unlock a new generation of computer chips, photovoltaic cells and other advanced materials.

Physics professor Moussa N’Gom, Ph.D., and materials science professor Edwin Fohtung, Ph.D., have brought together their respective areas of expertise—optics and —to illuminate previously unknown properties of the materials that will build the next generation of consumer, industrial and scientific devices.

“We can use almost the entire spectrum of light, from visible to X-ray, to manipulate and study materials,” Fohtung said. “We can interrogate any system, from hard condensed matter to soft biological tissue.”

Scientists Invent Plastic That Nature Eats 2,800 Feet Underwater

Scientists have unveiled a new biodegradable plastic that vanishes in one of the harshest environments on Earth—the deep sea.

In an experiment nearly 3,000 feet underwater, a bioengineered material called LAHB broke down while conventional plastics stayed intact. Deep-sea microbes not only colonized the plastic’s surface, but actively digested it using specialized enzymes, turning it into harmless byproducts. This breakthrough suggests a promising solution to the global plastic crisis, especially in oceans where most waste lingers for decades or centuries.

Global plastic waste problem still looms.

EnsembleAge: enhancing epigenetic age assessment with a multi-clock framework

Several widely used epigenetic clocks have been developed for mice and other species, but a persistent challenge remains: different mouse clocks often yield inconsistent results. To address this limitation in robustness, we present EnsembleAge, a suite of ensemble-based epigenetic clocks. Leveraging data from over 200 perturbation experiments across multiple tissues, EnsembleAge integrates predictions from multiple penalized models. Empirical evaluations demonstrate that EnsembleAge outperforms existing clocks in detecting both pro-aging and rejuvenating interventions. Furthermore, we introduce EnsembleAge HumanMouse, an extension that enables cross-species analyses, facilitating translational research between mouse models and human studies. Together, these advances underscore the potential of EnsembleAge as a robust tool for identifying and validating interventions that modulate biological aging.

A Paradigm Shift in Evolutionary Biology: The Extended Evolutionary Synthesis and the Role of Epigenetics

The field of evolutionary biology has a rich and complex history, marked by periods of consensus and significant theoretical shifts. The cornerstone of modern evolutionary thought for much of the 20th century was the Modern Synthesis (MS), a theoretical framework that integrated Darwin’s theory of natural selection with Mendelian genetics.

It provided a powerful and elegant explanation for how evolution occurs, emphasizing the gradual accumulation of genetic mutations and their differential survival in a population. However, in recent decades, a growing body of evidence has begun to challenge the sufficiency of the MS, leading to the development of a new, more comprehensive framework: the Extended Evolutionary Synthesis (EES).

A Review of the Current State of Magnetic Force Microscopy to Unravel the Magnetic Properties of Nanomaterials Applied in Biological Systems and Future Directions for Quantum Technologies

Magnetism plays a pivotal role in many biological systems. However, the intensity of the magnetic forces exerted between magnetic bodies is usually low, which demands the development of ultra-sensitivity tools for proper sensing. In this framework, magnetic force microscopy (MFM) offers excellent lateral resolution and the possibility of conducting single-molecule studies like other single-probe microscopy (SPM) techniques. This comprehensive review attempts to describe the paramount importance of magnetic forces for biological applications by highlighting MFM’s main advantages but also intrinsic limitations. While the working principles are described in depth, the article also focuses on novel micro- and nanofabrication procedures for MFM tips, which enhance the magnetic response signal of tested biomaterials compared to commercial nanoprobes. This work also depicts some relevant examples where MFM can quantitatively assess the magnetic performance of nanomaterials involved in biological systems, including magnetotactic bacteria, cryptochrome flavoproteins, and magnetic nanoparticles that can interact with animal tissues. Additionally, the most promising perspectives in this field are highlighted to make the reader aware of upcoming challenges when aiming toward quantum technologies.

Accelerating anti-aging cyclic peptide discovery through computational design and automated synthesis

Cyclic peptides, with their unique structures and versatile biological activities, hold great potential for combating skin aging issues such as wrinkles, laxity, and pigmentation. However, traditional discovery methods relying on iterative synthesis and screening are labor-intensive and resource-intensive. Here, we present an integrated platform combining automated rapid cyclopeptide synthesis, virtual screening, and biological activity assessment, enabling the transformation of designed cyclic peptide sequences into chemical entities within minutes with high crude purity. Using ADCP docking with the ADFR suite, we identified a series of novel cyclic peptides targeting JAK1, Keap1, and TGF-β proteins.

Chinese researchers unveil world’s largest-scale brain-like computer Darwin Monkey

Chinese researchers unveiled on Saturday a new generation of super large-scale brain-like computer, Darwin Monkey, the world’s first neuromorphic brain-like computer based on dedicated neuromorphic chips with over 2 billion neurons, which can mimic the workings of a macaque monkey’s brain.

Developed by the State Key Laboratory of Brain-Machine Intelligence at Zhejiang University in East China’s Zhejiang Province, Darwin Monkey, also known as Wukong supports over 2 billion spiking neurons and more than 100 billion synapses, with a neuron count approaching that of a macaque brain. It consumes approximately 2,000 watts of power under typical operating conditions, the Science and Technology Daily reported.

The human brain is like an extremely efficient “computer.” Brain-inspired computing applies the working principles of biological neural networks to computer system design, aiming to build computing systems that, like the brain, feature low power consumption, high parallelism, high efficiency, and intelligence.

/* */