Lifeboat Foundation

It is often said that empiricism is one of the most useful concepts in epistemology. Empiricism emphasises the role of experience acquired through one’s own senses and perceptions, and is contrary to, say, idealism where concepts are not derived from experience, but based on ideals.

In the case of radical life extension, there is a tendency to an ‘idealistic trance’ where people blindly expect practical biotechnological developments to be available and applied to the public at large within a few years. More importantly, idealists expect these treatments or therapies to actually be effective and to have a direct and measurable effect upon radical life extension. Here, by ‘radical life extension’ I refer not to healthy longevity (a healthy life until the age of 100–120 years) but to an indefinite lifespan where the rate of age-related mortality is trivial.

Let me mention two empirical examples based on experience and facts:

1. When a technological development depends on technology alone, its progress is often dramatic and exponential.

Continue reading “The Life Extension Hubris: Why biotechnology is unlikely to be the answer to ageing” »

Freedom fironically found in flesh, not knowing whe’er I’m foul or fowl… tickly bound neath trickly form twisting and more unfresh as dawn upon dawn dies in menstrual skyfire like blood made light — a mocking microcosm of my own transubstantiation from rotting viscera to lightstorm infinity?

Just what sick joke is this? To wake and ache and dream and be and become! – and then to die..? To culminate the very universe itself!.. and then to simply die?! For what I ask you! What! Death… what audacious greed! What reckless squander and heedless extravagance!

Guttural red fringed black a bulbous muck death bastphelgmy! We cannot comprehend the sheer stature of death and so hurriedly cover the unknown with a word to hold it in hand and at a distance, to doubt no doubt.

O pallid heavens! O incessant sun undaunted by my barrenaked finitude! O fetid sanctity wet and redragged as the sickly bloom of jagged flesh! O putrid night sky serene despite my spat fury; as I ebb and ember a’roil withinside my sadness unbelieving and hysteric animal heat that vile sun and auster night jaunt their jeer and mock the rude squall of my panicstrewn death nonetheless.

Continue reading “An Open Letter to Death” »

1. Thou shalt first guard the Earth and preserve humanity.

Impact deflection and survival colonies hold the moral high ground above all other calls on public funds.

2. Thou shalt go into space with heavy lift rockets with hydrogen upper stages and not go extinct.

Continue reading “Ten Commandments of Space” »

The Brain Games Begin
Europe’s billion-Euro science-neuro Human Brain Project, mentioned here amongst machine morality last week, is basically already funded and well underway. Now the colonies over in the new world are getting hip, and they too have in the works a project to map/simulate/make their very own copy of the universe’s greatest known computational artifact: the gelatinous wad of convoluted electrical pudding in your skull.

The (speculated but not yet public) Brain Activity Map of America
About 300 different news sources are reporting that a Brain Activity Map project is outlined in the current administration’s to-be-presented budget, and will be detailed sometime in March. Hoards of journalists are calling it “Obama’s Brain Project,” which is stoopid, and probably only because some guy at the New Yorker did and they all decided that’s what they had to do, too. Or somesuch lameness. Or laziness? Deference? SEO?

For reasons both economic and nationalistic, America could definitely use an inspirational, large-scale scientific project right about now. Because seriously, aside from going full-Pavlov over the next iPhone, what do we really have to look forward to these days? Now, if some technotards or bible pounders monkeywrench the deal, the U.S. is going to continue that slide toward scientific… lesserness. So, hippies, religious nuts, and all you little sociopathic babies in politics: zip it. Perhaps, however, we should gently poke and prod the hard of thinking toward a marginally heightened Europhobia — that way they’ll support the project. And it’s worth it. Just, you know, for science.

Going Big. Not Huge, But Big. But Could be Massive.
Both the Euro and American flavors are no Manhattan Project-scale undertaking, in the sense of urgency and motivational factors, but more like the Human Genome Project. Still, with clear directives and similar funding levels (€1 billion Euros & $1–3 billion US bucks, respectively), they’re quite ambitious and potentially far more world changing than a big bomb. Like, seriously, man. Because brains build bombs. But hopefully an artificial brain would not. Spaceships would be nice, though.

Continue reading “Human Brain Mapping & Simulation Projects: America Wants Some, Too?” »

The Golden Rule is Not for Toasters
Simplistically nutshelled, talking about machine morality is picking apart whether or not we’ll someday have to be nice to machines or demand that they be nice to us.

Well, it’s always a good time to address human & machine morality vis-à-vis both the engineering and philosophical issues intrinsic to the qualification and validation of non-biological intelligence and/or consciousness that, if manifested, would wholly justify consideration thereof.

Uhh… yep!

But, whether at run-on sentence dorkville or any other tech forum, right from the jump one should know that a single voice rapping about machine morality is bound to get hung up in and blinded by its own perspective, e.g., splitting hairs to decide who or what deserves moral treatment (if a definition of that can even be nailed down), or perhaps yet another justification for the standard intellectual cul de sac:
“Why bother, it’s never going to happen.“
That’s tired and lame.

Continue reading “Machine Morality: a Survey of Thought and a Hint of Harbinger” »

I recently posted this on the only two other sites that will allow me to express my opinions;

I see the problem as one of self similarity; trying to go cheap being the downfall of all these schemes to work around human physiology.

When I first became interested in space travel several years ago I would comment on a couple blogs and find myself constantly arguing with private space proponents- and saying over and over again, “there is no cheap.” I was finally excommunicated from that bunch and banned from posting. They would start calling me an idiot and other insults and when I tried to return the favor the moderator would block my replies. The person who runs those two sites works for a firm promoting space tourism- go figure.

The problem is that while the aerospace industry made some money off the space program as an outgrowth of the military industrial complex, it soon became clear that spaceships are hard money- they have to work. The example of this is the outrage over the Apollo 1 fire and subsequent oversight of contractors- a practice which disappeared after Apollo and resulted in the Space Shuttle being such a poor design. A portion of the shuttle development money reportedly went under the table into the B-1 bomber program; how much we will never know. Swing wings are not easy to build which is why you do not see it anymore; cuts into profits.

Continue reading “Explaining Space Travel” »

…here’s Tom with the Weather.
That right there is comedian/philosopher Bill Hicks, sadly no longer with us. One imagines he would be pleased and completely unsurprised to learn that serious scientific minds are considering and actually finding support for the theory that our reality could be a kind of simulation. That means, for example, a string of daisy-chained IBM Super-Deep-Blue Gene Quantum Watson computers from 2042 could be running a History of the Universe program, and depending on your solipsistic preferences, either you are or we are the character(s).

It’s been in the news a lot of late, but — no way, right?

Because dude, I’m totally real
Despite being utterly unable to even begin thinking about how to consider what real even means, the everyday average rational person would probably assign this to the sovereign realm of unemployable philosophy majors or under the Whatever, Who Cares? or Oh, That’s Interesting I Gotta Go Now! categories. Okay fine, but on the other side of the intellectual coin, vis-à-vis recent technological advancement, of late it’s actually being seriously considered by serious people using big words they’ve learned at endless college whilst collecting letters after their names and doin’ research and writin’ and gettin’ association memberships and such.

So… why now?

Continue reading “Today, a Young Man on Acid Realized that all Matter is Merely Energy Condensed to a...” »

I have been meaning to read a book coming out soon called Regenesis: How Synthetic Biology Will Reinvent Nature and Ourselves. It’s written by Harvard biologist George Church and science writer Ed Regis. Church is doing stunning work on a number of fronts, from creating synthetic microbes to sequencing human genomes, so I definitely am interested in what he has to say. I don’t know how many other people will be, so I have no idea how well the book will do. But in a tour de force of biochemical publishing, he has created 70 billion copies. Instead of paper and ink, or pdf’s and pixels, he’s used DNA.

Much as pdf’s are built on a digital system of 1s and 0s, DNA is a string of nucleotides, which can be one of four different types. Church and his colleagues turned his whole book–including illustrations–into a 5.27 MB file–which they then translated into a sequence of DNA. They stored the DNA on a chip and then sequenced it to read the text. The book is broken up into little chunks of DNA, each of which has a portion of the book itself as well as an address to indicate where it should go. They recovered the book with only 10 wrong bits out of 5.27 million. Using standard DNA-copying methods, they duplicated the DNA into 70 billion copies.

Scientists have stored little pieces of information in DNA before, but Church’s book is about 1,000 times bigger. I doubt anyone would buy a DNA edition of Regenesis on Amazon, since they’d need some expensive equipment and a lot of time to translate it into a format our brains can comprehend. But the costs are crashing, and DNA is a far more stable medium than that hard drive on your desk that you’re waiting to die. In fact, Regenesis could endure for centuries in its genetic form. Perhaps librarians of the future will need to get a degree in biology…

Link to Church’s paper

Source

Earth is a hostile place — and that’s even before one starts attending school. Even when life first sparked into being, it had to evolve defenses to deal with a number of toxins, such as damaging ultraviolet light, then there were toxic elements ranging from iron to oxygen to overcome, later, there was DDT and other toxic chemicals and of course, there are all those dreaded cancers.

In Evolution In A Toxic World: How Life Responds To Chemical Threats [Island Press; 2012: Guardian Bookshop; Amazon UK;Amazon US], environmental toxicologist Emily Monosson outlines three billion years of evolution designed to withstand the hardships of living on this deadly planet, giving rise to processes ranging from excretion, transformation or stowing harmful substances. The subtitle erroneously suggests these toxins are only chemical in nature, but the author actually discusses more than this one subclass of toxins.

The method that arose to deal with these toxins is a plethora of specialised, targeted proteins — enzymes that capture toxins and repair their damages. By following the origin and progression of these shared enzymes that evolved to deal with specific toxins, the author traces their history from the first bacteria-like organisms to modern humans. Comparing the new field evolutionary toxicology to biomedical research, Dr Monosson notes: “In light of evolution, biomedical researchers are now asking questions that might seem antithetical to medicine”.

Continue reading “Evolution in a Toxic World”