Lifeboat Foundation: Safeguarding Humanity
Toggle light / dark theme

Blog

Category: bioengineering – Page 203

The future frontier for hackers is synthetic biology.

Landmark scientific projects such as the Human Genome Project can encourage international cooperation and bring nations together. However, when security interests and defence research align with the prestige of a landmark project—international competition is all but assured. Synthetic biology is a scientific discipline less than a decade old, and the potential defence and security applications may create a new space race, this time between the USA and China.

The larger concern is not that this race may happen, but that if it does it will politicise and militarise an ethically sensitive area of the life sciences at a time when this frontier technology is critical to maintaining a sustainable world.

The Human Genome Project (HGP) cost about US$300 million (A$394 million), involved 20 international institutions and sequenced the human genome in just over a decade. The draft sequence was published in February 2001 and has driven economic, health and social benefits the world over for the last 15 years. To a very large extent this research project underpins the modern life sciences and is the equivalent of landing on the moon.

Continue reading “The Science of a New Space Race” | >

For decades, scientists have tried to harness the unique properties of carbon nanotubes to create high-performance electronics that are faster or consume less power — resulting in longer battery life, faster wireless communication and faster processing speeds for devices like smartphones and laptops.

But a number of challenges have impeded the development of high-performance transistors made of carbon nanotubes, tiny cylinders made of carbon just one atom thick. Consequently, their performance has lagged far behind semiconductors such as silicon and gallium arsenide used in computer chips and personal electronics.

Now, for the first time, University of Wisconsin–Madison materials engineers have created carbon nanotube transistors that outperform state-of-the-art silicon transistors.

Read more

I remember 4 years ago at a CIO Life Sciences Conference in AZ when one of the leaders over a research lab mention the desire to finally enable patients to share their entire DNA sequence on a thumb drive with their doctor in order to be treated properly as well as have insights on the patient’s future risks. However, limitations such as HIPAA was brought up in the discussion. Personally, with how we’re advancing things like synthetic biology which includes DNA data storage, cell circuitry, electronic tattoos, etc. thumb drive maybe too outdated.

The circle that is personalized medicine consists of more than just doctor, patient, and patient data. Other elements are in the loop, such as EHR systems that incorporate gene-drug information and updated clinical guidelines.

Read more

Chromatin proteins have expanded the mammalian synthetic biology toolbox by enabling control of active and silenced states at endogenous genes. Others have reported synthetic proteins that bind DNA and regulate genes by altering chromatin marks, such as histone modifications. Previously we reported the first synthetic transcriptional activator, the “Polycomb-based transcription factor” (PcTF), that reads histone modifications through a protein-protein interaction between the PCD motif and trimethylated lysine 27 of histone H3 (H3K27me3). Here, we describe the genome-wide behavior of PcTF. Transcriptome and chromatin profiling revealed PcTF-sensitive promoter regions marked by proximal PcTF and distal H3K27me3 binding. These results illuminate a mechanism in which PcTF interactions bridge epigenetic marks with the transcription initiation complex. In three cancer-derived human cell lines tested here, many PcTF-sensitive genes encode developmental regulators and tumor suppressors. Thus, PcTF represents a powerful new fusion-protein-based method for cancer research and treatment where silencing marks are translated into direct gene activation.

Read more

OAHU, HAWAI’I —(ENEWSPF)–September 1, 2016. As thousands of government representatives and conservationists convene in Oahu this week for the 2016 World Conservation Congress, international conservation and environmental leaders are raising awareness about the potentially dangerous use of gene drives — a controversial new synthetic biology technology intended to deliberately cause targeted species to become extinct.

Members of the International Union for the Conservation of Nature (IUCN), including NGOs, government representatives, and scientific and academic institutions, overwhelmingly voted to adopt a de facto moratorium on supporting or endorsing research into gene drives for conservation or other purposes until the IUCN has fully assessed their impacts. News of the August 26 digital vote comes as an important open letter to the group is being delivered.

Scientists and environmental experts and organizations from around the globe have advocated for a halt to proposals for the use of gene drive technologies in conservation. Announced today, a long list of environmental leaders, including Dr. Jane Goodall, DBE, genetics professor and broadcaster Dr. David Suzuki, Dr. Fritjof Capra, entomologist Dr. Angelika Hilbeck, Indian environmental activist Dr. Vandana Shiva and organic pioneer and biologist Nell Newman, have lent their support to the open letter: “A Call for Conservation with a Conscience: No Place for Gene Drives in Conservation.” The letter states, in part: “Gene drives, which have not been tested for unintended consequences, nor fully evaluated for ethical and social impacts, should not be promoted as conservation tools.”

Read more

In a video uploaded to YouTube on August 3rd (below), engineers from the Russian space agency, Roscosmos, proposed an orbiter and lander mission to Ganymede. The video suggests a launch could come in the next decade. Although the commentary is in Russian, the video appears to suggest that Ganymede may be as good a candidate or better for life than Europa.

Read more

Singularity University Global Summit is the culmination of the Exponential Conference Series and the definitive place to witness converging exponential technologies and understand how they’ll impact the world.

How many cyborgs did you see during your morning commute today? I would guess at least five. Did they make you nervous? Probably not; you likely didn’t even realize they were there.

In a presentation titled “Biohacking and the Connected Body” at Singularity University Global Summit, Hannes Sjoblad informed the audience that we’re already living in the age of cyborgs. Sjoblad is co-founder of the Sweden-based biohacker network Bionyfiken, a chartered non-profit that unites DIY-biologists, hackers, makers, body modification artists and health and performance devotees to explore human-machine integration.

Read more

Luv this article because it hits a very important topic of how will things change with BMI/ mind control technology in general. For example with BMI will we need wearable devices? if so, what type and why? Also, how will banking, healthcare, businesses, hospitality, transportation, media and entertainment, communications, government, etc. in general will change with BMI and AI together? And, don’t forget cell circuitry, and DNA storage and processing capabilities that have been proven to date and advancing.

When you take into account what we are doing with synthetic biology, BMI, AI, and QC; we are definitely going to see some very amazing things just within the next 10 years alone.

Neuroscientists have just demonstrated that we can control drones with our minds. Find out how this shapes the future of digital marketing.

Continue reading “What Mind-Controlled Drones Mean for the Future of Digital Marketing” | >

Excellent opportunity.

Dolomite microfluidic chips are helping researchers from the Biodesign Institute at Arizona State University (ASU) to develop novel enzymes capable of polymerising synthetic nucleotides.

dolomiteUsing these chips, the team has created a droplet-based optical polymerase sorting (DrOPS) technique allowing rapid screening for novel polymerase activities in uniform water-in-oil microcompartments. The team’s leader, Professor John C. Chaput – formerly at ASU and currently at the University of California, Irvine – explained: “The creation of synthetic nucleic acids is of great interest to synthetic biologists but, because they are not found in nature, wild type polymerases struggle to process them. To overcome this issue, we are developing novel polymerases using directed evolution in water-in-oil microcompartments. The DrOPS methodology has significant advantages over traditional methods, which are both labour intensive and impractical to perform on a large scale due to the amount of precious artificial nucleotide reagents required for screening.”

The Biodesign Institute turned to microfluidics to allow rapid sorting and screening of novel polymerases, taking advantage of the technique’s single-cell encapsulation capabilities and picolitre reaction volumes. Dr Andrew Larsen commented: “We needed very reproducible microfluidics, and so using commercially available chips was preferable. We already had experience with Dolomite’s chips for a variety of applications within the institute, and they have always been very consistent, so the choice was obvious. These chips give us the ability to consistently generate uniform droplets – both single and double emulsion droplets – offering spatial separation between cells and allowing fluorescence-based sorting using conventional FACS technologies. Dolomite has also been very supportive of our efforts, helping to accelerate this area of research.”

Read more