Archive for the ‘bioengineering’ category: Page 2

Oct 24, 2020

New CRISPR-Based Imaging Tool Is Going to Be HiUGE

Posted by in categories: bioengineering, biotech/medical, genetics

A team of researchers at Duke University have developed an imaging technology for tagging structures at a cellular level that overcomes the shortcomings of existing antibody-based techniques. Immunofluorescence imaging is a key part of the cell biologist’s toolbox, in which a fluorescent ‘flare’ attached to an antibody allows them to visualize the presence of specific target proteins in cell or tissue samples. The issue is that this specificity isn’t always 100 percent — sometimes the antibodies bind to other closely related proteins as well, making it difficult to interpret the results.

Duke’s cell biology chair Scott Soderling has led a team that developed Homology-independent Universal Genome Engineering (HiUGE), an innovation that uses gene-editing technology to rise above the shortcomings of traditional commercial antibodies for imaging.

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Oct 24, 2020

CRISPR turns normal body fat into a type that burns energy

Posted by in categories: bioengineering, biotech/medical

Animal studies suggest the metabolic conditions linked to obesity could be treated by using CRISPR gene editing to turn normal fat into heat-producing beige fat.

Oct 23, 2020

Google / Alphabet’s Quest to Solve Aging

Posted by in categories: bioengineering, biotech/medical, genetics, life extension

Dr. Adam Freund PhD., Calico Life Sciences, Discussing Google Quest to Solve Aging.

Ira Pastor, ideaXme life sciences ambassador interviews Dr Adam Freund, PhD, Principal Investigator at Calico Life Sciences (Calico).

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Oct 22, 2020

How Synthetic Biology Can Help the Environment

Posted by in categories: bioengineering, biological, climatology, sustainability

Artificial and modified organisms could become essential tools to fight climate change, clean up pollution, protect biodiversity, and more.

Oct 19, 2020

CRISPR-induced immune diversification in host-virus populations

Posted by in categories: bioengineering, biotech/medical, evolution

Just like humans, microbes have equipped themselves with tools to recognize and defend themselves against viral invaders. In a continual evolutionary battle between virus and host, CRISPR-Cas act as a major driving force of strain diversity in host-virus systems.

A new study led by Professor of Life Sciences Shai Pilosof (Ben-Gurion University of the Negev, Beer-Sheva, Israel), Professor of Microbiology Rachel Whitaker (University of Illinois Urbana-Champaign), and Professor of Ecology and Evolution Mercedes Pascual (University of Chicago) highlights the role of diversified immunity in mediating -pathogen interactions and its eco-evolutionary dynamics. The study also included Professor of Bioengineering and Bliss Faculty Scholar Sergei Maslov (University of Illinois Urbana-Champaign), Sergio A. Alcal´a-Corona (University of Chicago), and Ph.D. graduate students Ted Kim and Tong Wang (University of Illinois Urbana-Champaign).

Their findings were reported in the journal Nature Ecology & Evolution.

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Oct 18, 2020

Autopsies Show Microplastics in Major Human Organs

Posted by in categories: bioengineering, biotech/medical, chemistry, health

It looks like micro-plastics are now found inside human bodies.

Researchers found evidence of plastic contamination in tissue samples taken from the lungs, liver, spleen and kidneys of donated human cadavers.

“We have detected these chemicals of plastics in every single organ that we have investigated,” said senior researcher Rolf Halden, director of the Arizona State University (ASU) Biodesign Center for Environmental Health Engineering.

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Oct 17, 2020

[Burning Issue] CRISPR Technology and Associated Concerns

Posted by in categories: bioengineering, biotech/medical, chemistry, genetics

We ask students to login via google as we share a lot of our content over google drive. To access the same, a google account is a must.

The CRISPR-Cas9 system has revolutionized genetic manipulations and made gene editing simpler, faster and easily accessible to most laboratories.

To its recognition, this year, the French-American duo Emmanuelle Charpentier and Jennifer Doudna have been awarded the prestigious Nobel Prize for chemistry for CRISPR.

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Oct 15, 2020

Harvard Fellow: Next Pandemic Could Be Engineered by Terrorists

Posted by in categories: bioengineering, biotech/medical

Experts say that COVID-19 almost certainly arose naturally, rather than being bioengineered.

But that doesn’t mean the next pandemic won’t involve a deadly virus designed by an adversary, as distinguished fellow at Harvard Law Vivek Wadhwa argues in a new essay for Foreign Policy.

“It is now too late to stop the global spread of these technologies — the genie is out of the bottle,” he wrote. “We must treat the coronavirus pandemic as a full dress rehearsal of what is to come — unfortunately, that includes not only viruses that erupt from nature, but also those that will be deliberately engineered by humans.”

Oct 8, 2020

Engineers create nanoparticles that deliver gene-editing tools to specific tissues and organs

Posted by in categories: bioengineering, biotech/medical, chemistry, genetics, nanotechnology, neuroscience

One of the most remarkable recent advances in biomedical research has been the development of highly targeted gene-editing methods such as CRISPR that can add, remove, or change a gene within a cell with great precision. The method is already being tested or used for the treatment of patients with sickle cell anemia and cancers such as multiple myeloma and liposarcoma, and today, its creators Emmanuelle Charpentier and Jennifer Doudna received the Nobel Prize in chemistry.

While is remarkably precise in finding and altering genes, there is still no way to target treatment to specific locations in the body. The treatments tested so far involve removing or immune system T cells from the body to modify them, and then infusing them back into a patient to repopulate the bloodstream or reconstitute an immune response—an expensive and time-consuming process.

Building on the accomplishments of Charpentier and Doudna, Tufts researchers have for the first time devised a way to directly deliver gene-editing packages efficiently across the and into specific regions of the brain, into immune system cells, or to specific tissues and organs in mouse models. These applications could open up an entirely new line of strategy in the treatment of neurological conditions, as well as cancer, infectious disease, and autoimmune diseases.

Oct 8, 2020

Some Fish Can Regenerate Their Eyes. Turns Out, Mammals Have Those Genes Too

Posted by in categories: bioengineering, biotech/medical, life extension

Perhaps in the future, gene editing may allow retinal regeneration in humans to reverse age-related vision deterioration.

Damage to the retina is the leading cause of blindness in humans, affecting millions of people around the world. Unfortunately, the retina is one of the few tissues we humans can’t grow back.

Unlike us, other animals such as zebrafish are able to regenerate this tissue that’s so crucial to our power of sight. We share 70 percent of our genes with these tiny little zebrafish, and scientists have just discovered some of the shared genes include the ones that grant zebrafish the ability to grow back their retinas.

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