Lifeboat Foundation

Scientists have been working for decades on engineered viruses that can hunt down and get inside cancer cells, cause them to burst and spur the immune system to mop up whatever malignant cells might be left behind. Only one such treatment has successfully become an FDA-approved cancer treatment.

That one drug, from Amgen, isn’t selling much. But that small victory a year ago has emboldened others to go forward with their own ideas to advance this approach to cancer therapy, known as oncolytic virus therapy.

One of the aspiring players in the oncolytic virus field, Ottawa, Canada-based Turnstone Biologics, is announcing today it has raised $41.4 million in a Series B venture financing. The round was led by OrbiMed Advisors, and included F-Prime Capital Partners and a couple of existing investors, FACIT and Versant Ventures. The new money will add on to the $11.3 million Series A round from a year ago.

Continue reading “Engineering Viruses to Kill Cancer Cells, Canada-Based Turnstone Raises $41.4M” »

Everything you wanted to know about gene editing but were affraid to ask!

Researchers at the University of California in San Diego have found a way to use gene editing technology to target RNA in living cells.

Bioquark Inc. (www.bioquark.com) Interview in MoneyWeek

Read whole story: http://moneyweek.com/who-wants-to-live-forever/

Anyone who does not have QC as part of their 5+Yr Roadmap for IT are truly exposing their company as well as shareholders and customers. China, Russia, Cartels, DarkNet, etc. will use the technology to extort victims, destroy companies, economies, and complete countries where folks have not planned, budget, skilled up, and prep for full replacement of their infrastructure and Net access. Not to mention companies who have this infrastructure will provide better services/ CCE to svc. consumers.

In a recent article, we highlighted a smart beta ETF called the “Sprott BUZZ Social Media Insights ETF” that uses artificial intelligence (AI) to select and weight stocks. If we stop and think about that for a moment, that’s a pretty cool use of AI that seems well ahead of its time. Now we’re not saying that you should go out and buy this smart beta ETF right away. It uses social media data. We know that on social media, everyone’s an expert and many of the opinions that are stated are just that, opinions. However some of the signals may be legitimate. Someone who just bought Apple is likely to go on telling everyone how bullish they are on Apple shares. Bullish behavior is often accompanied by bullish rhetoric. And maybe that’s exactly the point, but the extent to which we’re actually using artificial intelligence here is not that meaningful. Simple scripting tools go out and scrape all this public data and then we use natural language processing (NLP) algorithms to determine if the data artifacts have a positive or negative sentiment. That’s not that intelligent, is it? This made us start to think about what it would take to create a truly “intelligent” smart beta ETF.

What is Smart Beta?

Continue reading “How Smart Beta ETFs of the Future Will Use AI” »

The field, or at least the widely used term, of synthetic biology (synbio) started nearly two decades ago. As the field has matured, two PLoS ONE papers have analyzed the publishing data to look at trends, language, and connections among synbio researchers. This data provides snapshots of who’s publishing, what kind of research is being published, when it’s being published, and where it’s being published. The question of why is certainly open for interpretation but the growth dynamics of synthetic biology publishing can give some sense of why a the term has stuck as a useful unifying term.

In 2012, researchers used Thomson Reuters Web of Science publishing data to map where people are publishing synbio research, how those people are connected, and who’s funding it. More recently, three French researchers also used data from the Thomson Reuters Web of Science to assess how synthetic biology the different areas of synthetic biology have grown and interacted.

Both of these papers draw interesting pictures of how new terms and ideas spread within an new umbrella term for a kind of research. Together these two papers paint give us some answers to the ‘Who, What, When, Where, & Why’ of synthetic biology.

Why compliance exist.

Gingko Bioworks launched their new laboratory last month—an automated “factory” that mass-produces genetically modified organisms. The organism company’s tagline is “Biology By Design,” and it aims to deliver just that in their second foundry, which is equipped with numerous robots that mash together huge batches of genes to churn out new and exotic lifeforms […] Gingko is ambitiously working through the complexities of biology and genetics to create these experimental organisms. The company boasts of a design-build-test cycle: gene-enzyme mixes designed from the company’s scientific database is put together in a hundred different ways, and the “mashup” that services a client’s needs best is accepted as the new organism’s genetic profile. Their new liquid-handling robots like the Echo 525 make large-scale experimentation possible. (READ MORE)

Continue reading “As In The Days Of Noah—New Synthetic Biology Factory Will Design, Build, And Test Exotic New Lifeforms” »

Continue reading “10 companies that want to make chemotherapy easier for patients — Bioquark Inc.” »

The idea of a genetic mutation spreading rapidly through a population isn’t as far-fetched a possibility as it once was.

Tissue engineering makes further progress for repairing damaged joints.

Writing in The Lancet, Swiss doctors report that cartilage cells harvested from patients’ own noses have been used to successfully produce cartilage transplants for the treatment of the knees of 10 adults (aged 18–55 years) whose cartilage was damaged by injury. Two years after reconstruction, most recipients reported improvements in pain, knee function, and quality of life, as well as developing repair tissue that is similar in composition to native cartilage.

Despite this promising start, however, the effectiveness of the procedure needs to be rigorously assessed in larger randomised trials compared to conventional treatments and with longer follow up before any firm conclusions can be drawn about its use in routine clinical practice, say the authors.

Continue reading “The Lancet: Swiss doctors report success of using cells from the nose to repair damaged knee joints 2 years post operation” »