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The introduction of the gene editing tool CRISPR in 2007 was a revolution in medical science and cell biology. But even though the potential is great, the launch of CRISPR has been followed by debate about ethical issues and the technology’s degree of accuracy and side effects.

However, in a new study published in Cell, from the Novo Nordisk Foundation Center for Protein Research have described how Cas12a, one of the CRISPR technologies, works at the molecular level. This makes it possible to fine-tune the gene-editing process to achieve specific desired effects.

“If we compare CRISPR to a car engine, what we have done is make a complete 3D map of the engine and thus gained an understanding of how it works. This knowledge will enable us to fine-tune the CRISPR engine and make it work in various ways—as a Formula 1 racer as well as an off-road truck,” says Professor Guillermo Montoya from the Novo Nordisk Foundation Center for Protein Research.

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Showrunner Jeff Buhler has built a fascinating world around Martin’s story seeds, starting by setting the action within the foreseeable future, rather than in an incomprehensibly distant one. The invented technologies here are particularly intriguing, like the genetic modifications first officer Melantha Jhirl (Jodie Turner-Smith) has to make her better suited for space travel, or the cybernetics technician Lommie (Maya Eshet) uses to interface with machinery. Given the state of real-world technological developments in genetic engineering and research into brain-machine interfaces, the series feels plausible and grounded, even though it’s set in a spacefaring future.


The 10-episode space series adapts a 40-year-old George R.R. Martin novella.

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A couple of days ago, news about the first designer babies has shaken the world. A Chinese researcher, Jiankui He, and his team at the Southern University of Science and Technology of China have been recruiting couples in order to create the world’s first babies with artificially increased resilience to HIV. The embryos were modified using the CRISPR/Cas9 gene editing tool before being implanted in their mother.

According to the research lead, the twins were born healthy a few weeks ago, and genetic testing performed after they were born confirmed that the editing had actually taken place. While the academic community discusses whether it is acceptable or not to modify human genes, taking into account that the changes made will be inherited by these babies’ offspring and are now added to mankind’s genetic pool, I want to share my own views on designer babies.

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Scientists have discovered a new chemical process—also known as a biosynthetic pathway—in bacteria which could lead to a new generation of antibiotics being produced and manufactured.

Researchers at The University of Manchester’s School of Chemistry say their new pathway includes an , called a carboxylase, which adds CO2 to a precursor molecule producing a highly unusual antibiotic called malonomycin.

The team says the biosynthetic process used to produce this antibiotic could now possibly lead to the discovery and development of other drugs, helping in the fight against drug-resistant bugs and illnesses in the future.

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Not sure if this is real or still vaporware yet. But it IS inevitable. It’s not a matter of “if”, but “when”. And we’re most likely not going to be able to regulate it much, either. If an embryo or fetus is not a human, then parents have the right to do anything they want to it. You might think that this is going to result in eugenics, like erasing melanin genes and starting a race against the fictitious “white genocide”. You’re right. But if you think that’s as bad as it’ll get, think more creatively. What happens when poor parents get paid to implant “willing servility” genes into their unborn children, in order to pay bills. The future is now. Cyborgs will not destroy humanity, but humanity itself might. What kinds of rights can be written into law to prevent this kind of extortion, that won’t also grant fetal personhood and end up derailing abortion rights? It’s going to be a bumpy ride, folks, buckle up!


A Chinese researcher claims he helped make the world’s first genetically edited babies — twin girls born this month, and with DNA he says he altered with a powerful new tool capable of rewriting the very blueprint of life.

If true, it would be a profound leap of science and ethics.

A U.S. scientist said he took part in the work in China, but this kind of gene editing is banned in the United States because the DNA changes can pass to future generations and risks harming other genes.

And so it begins…


HONG KONG (AP) — A Chinese researcher claims that he helped make the world’s first genetically edited babies — twin girls born this month whose DNA he said he altered with a powerful new tool capable of rewriting the very blueprint of life. If true, it would be a profound leap of science and ethics. A U.S. scientist said he took part in the work in China, but this kind of gene editing is banned in the United States because the DNA changes can pass to future generations and it risks harming other genes. Many mainstream scientists think it’s too unsafe to try, and some denounced the Chinese report as human experimentation.

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