The co-inventor of the groundbreaking gene editing technology talks to OneZero about a world where illness could be diagnosed in minutes.
Category: bioengineering – Page 149
But getting human cells to grow in another species is not easy. Nakauchi and colleagues announced at the 2018 American Association for the Advancement of Science meeting in Austin, Texas that they had put human iPS cells into sheep embryos that had been engineered not to produce a pancreas. But the hybrid embryos, grown for 28 days, contained very few human cells, and nothing resembling organs. This is probably because of the genetic distance between humans and sheep, says Nakauchi.
The research could eventually lead to new sources of organs for transplant, but ethical and technical hurdles need to be overcome.
Medicine has a “Goldilocks” problem. Many therapies are safe and effective only when administered at just the right time and in very precise doses – when given too early or too late, in too large or too small an amount, medicines can be ineffective or even harmful. But in many situations, doctors have no way of knowing when or how much to dispense.
Now, a team of bioengineers led by UC San Francisco’s Hana El-Samad, PhD, and the University of Washington’s David Baker, PhD, have devised a remarkable solution to this problem – “smart” cells that behave like tiny autonomous robots which, in the future, may be used to detect damage and disease, and deliver help at just the right time and in just the right amount.
Gene editing is advancing at a faster pace than most of us can keep up with. One significant recent announcement was gene editing tool CRISPR’s application to non-genetic diseases thanks to a new ability to edit single letters in RNA.
Even as CRISPR reaches milestones like this, scientists continue to find new uses for it to treat genetic conditions. The next one that will hit clinics is a CRISPR treatment for a form of blindness called Leber congenital amaurosis (LCA).
Having been approved by the FDA in December, the treatment will be the first of its kind to be trialed in the US.
A Sydney team has developed a box jellyfish antidote so simple it can go on as a spray. But it’s only the first step.
Hallucinations are spooky and, fortunately, fairly rare. But, a new study suggests, the real question isn’t so much why some people occasionally experience them. It’s why all of us aren’t hallucinating all the time.
In the study, Stanford University School of Medicine neuroscientists stimulated nerve cells in the visual cortex of mice to induce an illusory image in the animals’ minds. The scientists needed to stimulate a surprisingly small number of nerve cells, or neurons, in order to generate the perception, which caused the mice to behave in a particular way.
“Back in 2012, we had described the ability to control the activity of individually selected neurons in an awake, alert animal,” said Karl Deisseroth, MD, Ph.D., professor of bioengineering and of psychiatry and behavioral sciences. “Now, for the first time, we’ve been able to advance this capability to control multiple individually specified cells at once, and make an animal perceive something specific that in fact is not really there—and behave accordingly.”
https://www.prweb.com/releases/regenerage_international_iime…449142.htm
Scientists at Berkeley Lab have made a new material that is both liquid and magnetic, opening the door to a new area of science in magnetic soft matter. Their findings could lead to a revolutionary class of printable liquid devices for a variety of applications from artificial cells that deliver targeted cancer therapies to flexible liquid robots that can change their shape to adapt to their surroundings. (Video credit: Marilyn Chung/Berkeley Lab; footage of droplets courtesy of Xubo Liu and Tom Russell/Berkeley Lab)
A University of California, Berkeley professor stands at the front of the room, delivering her invited talk about the potential of genetic engineering. Her audience, full of organic farming advocates, listens uneasily. She notices a man get up from his seat and move toward the front of the room. Confused, the speaker pauses mid-sentence as she watches him bend over, reach for the power cord, and unplug the projector. The room darkens and silence falls. So much for listening to the ideas of others.
Many organic advocates claim that genetically engineered crops are harmful to human health, the environment, and the farmers who work with them. Biotechnology advocates fire back that genetically engineered crops are safe, reduce insecticide use, and allow farmers in developing countries to produce enough food to feed themselves and their families.
Now, sides are being chosen about whether the new gene editing technology, CRISPR, is really just “GMO 2.0” or a helpful new tool to speed up the plant breeding process. In July, the European Union’s Court of Justice ruled that crops made with CRISPR will be classified as genetically engineered. In the United States, meanwhile, the regulatory system is drawing distinctions between genetic engineering and specific uses of genome editing.