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Researchers have developed a new technique to produce a 3D ‘micro-printed’ array of needles capable of drug delivery. The technique would offer a pain-free drug delivery device that would allow drugs to diffuse within the body as the biomaterial device degrades in the body. This offers treatments for a wide range of diseases, including melanoma cancers.

The results are published today, Wednesday 30th September, in the journal Biofabrication .

The researchers, based at the University of Akron and the University of Texas, report producing a drug-loaded array for transdermal delivery of a chemotherapeutic drug, fabricated using microstereolithography. The arrays consisted of 25 poly(propylene fumarate) microneedles, each needle having a tip and base diameter of 20 µm and 200 µm, respectively, and a height of 1 mm.

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Reconstituting epithelial (skin) microtissues with programmed size, shape, composition, spatial heterogeneity, and embedding extracellular matrix. Scheme and images of fully embedded aggregates of human luminal and myoepithelial cells. (credit: Michael E Todhunter et al./Nature Methods)

A new technique developed by UCSF scientists for building organoids (tiny models of human tissues) more precisely turns human cells into the biological equivalent of LEGO bricks. Called DNA Programmed Assembly of Cells (DPAC), it allows researchers in hours to create arrays of thousands of custom-designed organoids, such as models of human mammary glands containing several hundred cells each.

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Just days ago it was announced that a 3D printed guide developed by researchers in Minnesota could help facilitate the regrowth of damaged nerves within the human body. In the wake of this exciting breakthrough, is another progressive use for 3D printing within the medical world, as the same researchers have found a way to release biomolecules into the body through a 3D printed scaffold with more precision than ever before.

Continue reading “3D printed scaffolds allow for precise release of biomolecules into the human body” »

Having significantly damaged nerve tissue is bad for a lot of reasons because it doesn’t regenerate easily and it can lead to various serious medical conditions including paralysis. But many scientists are already studying ways of fixing this issue, and a team of researchers from the University of Minnesota, Virginia Tech, University of Maryland, Princeton University, and Johns Hopkins University has figured out how to use 3D printing for nerve growth.

DON’T MISS: 85 legitimate iPhone apps that were infected with malware in the big App Store hack

Continue reading “Breakthrough medical discovery: 3D printing might be used to regenerate nerves” »

Shawn Frayne and Alex Hornstein, two young inventors based in the Philippines, are taking their passion for clean free energy and developing a way to make it accessible and cheap for everyone. These guys are working restlessly to provide a product that could be used by practically anyone to make homemade solar panels.

The factory is small enough to fit on a desktop and efficient enough to produce 300k to one million panels per year, up to one every 15 seconds. By cutting out much of the labor intensive process, which represents 50% of the total cost, this machine can dramatically reduce the price of solar. Their pocket solar panel producer can change the way the world views electricity. Image credit: YouTube/SciFri

Continue reading “Open Source ‘Solar Pocket Factory’ Can 3D Print a Solar Panel Every 15 Seconds” »

Called a shape-memory polymer (SMP) and developed by a team at Texas A&M University in the US, this biodegradable material can be used to fill in gaps in a damaged face and act as a scaffold to guide the growth of existing bones.

The researchers made their shape-memory polymer by linking molecules of another material — polycaprolactone, or PCL — and whipping it into a foam. According to Jackie Hong at Motherboard, the material is soft and easy to mould when heated to 60°C (140°F), and sets when it’s cooled to body temperature without becoming brittle. It can be used in 3D printing and moulding, which means it can be shaped into extremely precise models and bone scaffolds, and it’s full of tiny holes like a sponge, which allows bone-producing cells called osteoblasts to collect inside and grow.

According to Hong, the researchers enhanced this osteoblast-growing effect by coating their SMP material in polydopamine — a different kind of polymer substance that helps bind existing bones to the SMP scaffold, and has been shown in previous studies to encourage the growth of osteoblasts. Over a three-day trial, their coated SMP scaffold grew five times more osteoblasts than their uncoated scaffold.

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The future of affordable (and sustainable) housing may lie with 3D printing. The World’s Advanced Saving Project (WASP) will soon unveil the world’s largest delta-style 3D printer that can build full-size buildings out of mud and clay for nearly zero cost. The massive 12-meter-tall (40 feet) BigDelta printer will make its official debut and show off its eco-friendly printing prowess tomorrow at “Reality of dream,” a three-day event in Massa Lombarda, Italy.

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Researchers at MIT and Boston Children’s Hospital have developed a system that can take MRI scans of a patient’s heart and, in a matter of hours, convert them into a tangible, physical model that surgeons can use to plan surgery.

The models could provide a more intuitive way for surgeons to assess and prepare for the anatomical idiosyncrasies of individual patients. “Our collaborators are convinced that this will make a difference,” says Polina Golland, a professor of electrical engineering and computer science at MIT, who led the project. “The phrase I heard is that ‘surgeons see with their hands,’ that the perception is in the touch.”

This fall, seven cardiac surgeons at Boston Children’s Hospital will participate in a study intended to evaluate the models’ usefulness.

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Solar power has been gaining more and more popularity worldwide since the efficiency of solar panels has significantly increased during the recent years, along with the dramatic decrease in the costs. However, its popularity is not only due its affordability to a wider audience but also to the growing awareness about the benefits of clean sources of energy. Yet, the costs of transportation and production often make it extremely difficult to implement solar technology in developing countries. Printed solar cells could offer a solution to this problem.

Thanks to the advances in printed solar cell technology during the past few years, its energy efficiency has increased from 3% to 20%.

“Its success is due to its cost-effectiveness and simplicity. A 10×10 cm solar cell film is enough to generate as much as 10–50 watts per square meter,” said Scott Watkins from the Korean company Kyung-In Synthetic.

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