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A Band-Aid for the Heart? New 3D Printing Method makes this, and much more, possible

In the quest to develop life-like materials to replace and repair human body parts, scientists face a formidable challenge: Real tissues are often both strong and stretchable and vary in shape and size.

A CU Boulder-led team, in collaboration with researchers at the University of Pennsylvania, has taken a critical step toward cracking that code. They’ve developed a new way to 3D print material that is at once elastic enough to withstand a heart’s persistent beating, tough enough to endure the crushing load placed on joints, and easily shapable to fit a patient’s unique defects.

Better yet, it sticks easily to wet tissue.

Mucus-based bioink could be used to Print and Grow Lung Tissue

#bioink could be used to #Print and #Grow #Lung #Tissue.

Researchers describe their success in creating a mucus-based bioink for 3D printing lung tissue. This advancement could one day help study and treat chronic lung conditions. scitechupdates.com/mucus-based-bi


Lung diseases kill millions of people around the world each year. Treatment options are limited, and animal models for studying these illnesses and experimental medications are inadequate. Now, writing in ACS Applied Bio Materials, researchers describe their success in creating a mucus-based bioink for 3D printing lung tissue. This advancement could one day help study and treat chronic lung conditions.

While some people with lung diseases receive transplants, donor organs remain in short supply. As an alternative, medications and other treatments can be used to manage symptoms, but no cure is available for disorders such as chronic obstructive pulmonary disease and cystic fibrosis. Researchers continue to seek better medications, often relying on testing in rodents. But these animal models may only partially capture the complexities of pulmonary diseases in humans, and they might not accurately predict the safety and efficacy of new drugs.

Meanwhile, bioengineers are exploring the production of lung tissue in the lab, either as a more accurate model to study human lungs or as a potential material to use in implants. One technique involves 3D printing structures that mimic human tissue, but designing a suitable bioink to support cell growth remains challenging. So, Ashok Raichur and colleagues set out to overcome this obstacle.

3D-printed decoupled structural lithium-ion batteries that are stable, robust and customizable

The widespread adoption of electric vehicles greatly relies on the development of robust and fast-charging battery technologies that can support their continuous operation for long periods of time. One proposed energy storage solution to improve the endurance of electric vehicles entails the use of so-called structural batteries.

Structural batteries are batteries that can serve two purposes, acting both as structural components of vehicles and solutions. Instead of being external components that are added to an electronic or electric device, these batteries are thus directly embedded into the structure.

Researchers at Shanghai University and their collaborators recently devised a promising strategy to fabricate highly performing structural batteries with customizable geometric configurations. Their strategy, outlined in a paper published in Composites Science and Technology, enables the 3D-printing of structural lithium-ion batteries for different geometrical configurations.

Fully 3D-printed shape memory mini-actuators can move small soft robots

Researchers from North Carolina State University have demonstrated miniature soft hydraulic actuators that can be used to control the deformation and motion of soft robots that are less than a millimeter thick. The researchers have also demonstrated that this technique works with shape memory materials, allowing users to repeatedly lock the soft robots into a desired shape and return to the original shape as needed.

“Soft robotics holds promise for many applications, but it is challenging to design the actuators that drive the motion of soft robots on a small scale,” says Jie Yin, corresponding author of a paper on the work (Advanced Materials, “Fully 3D-Printed Miniature Soft Hydraulic Actuators with Shape Memory Effect for Morphing and Manipulation”) and an associate professor of mechanical and aerospace engineering at NC State. “Our approach makes use of commercially available multi-material 3D printing technologies and shape memory polymers to create soft actuators on a microscale that allow us to control very small soft robots, which allows for exceptional control and delicacy.”

The new technique relies on creating soft robots that consist of two layers. The first layer is a flexible polymer that is created using 3D printing technologies and incorporates a pattern of microfluidic channels – essentially very small tubes running through the material. The second layer is a flexible shape memory polymer. Altogether, the soft robot is only 0.8 millimeters thick.

Custom Implants on Demand? Bandages for the Heart? 3D Printing Method Makes It Possible

University of Colorado at Boulder News

In the quest to develop life-like materials to replace and repair human body parts, scientists face a formidable challenge: Real tissues are often both strong and stretchable and vary in shape and size.

A CU Boulder-led team, in collaboration with researchers at the University of Pennsylvania, has taken a critical step toward cracking that code. They’ve developed a new way to 3D print material that is at once elastic enough to withstand a heart’s persistent beating, tough enough to endure the crushing load placed on joints, and easily shapable to fit a patient’s unique defects.

3D-Printing Heart Tissue With Human Stem Cells

Year 2023 face_with_colon_three


Scientists at Stanford University have developed a method for 3D-printing human heart tissue that could eventually be implanted into patients.

0:00 Intro.
0:45 How scientists are 3D Printing heart parts.
1:25 Bioprinting process.
2:45 Bio-printed heart valve.
3:44 Outro.

Read the CNET article.
Stanford Scientists Use Stem Cells to 3D-Print Heart Tissue.
https://www.cnet.com/science/stanford

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3D laser printing with bioinks from microalgae

Microalgae such as the diatom Odontella aurita and the green alga Tetraselmis striata are especially suitable as “biofactories” for the production of sustainable materials for 3D laser printing due to their high content in lipids and photoactive pigments. An international research team led by Prof. Dr Eva Blasco, a scientist at the Institute for Molecular Systems Engineering and Advanced Materials (IMSEAM) of Heidelberg University, has succeeded for the first time in manufacturing inks for printing complex biocompatible 3D microstructures from the raw materials extracted from the microalgae. The microalgae-based materials could be used in future as the basis for implants or scaffolds for 3D cell cultures.

The research has been published in Advanced Materials (“Printing Green: Microalgae-Based Materials for 3D Printing with Light”).

A new ink system, based on the microalgae Odontella aurita and Tetraselmis striata, enables the manufacturing of complex 3D microstructures with high quality and precision. (Image: Clara Vazquez-Martel)