In a recent study published in Nature Cancer, a team of researchers investigated the unique structure of deoxyribonucleic acid (DNA) in extracellular vesicles (EVs) and its role in cancer progression.
The study examined how EV-DNA, through its association with histones, influences immune cell responses and impacts the pre-metastatic niche. It also explored how it could serve as a predictive biomarker for metastasis, especially in colorectal cancer.
The study highlights how EV-DNA packaging influences immune responses and its promise as a biomarker for assessing colorectal cancer metastasis risk.
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