Menu

Blog

Dec 7, 2023

Phage-assisted evolution of compact Cas9 variants targeting a simple NNG PAM

Posted by in category: evolution

Qi et al. used phage-assisted evolution to optimize SlugCas9, a compact Cas9 nuclease, for NNG PAM recognition and developed a SlugCas9-NNG based adenine base editor for single AAV delivery.

Comments are closed.