Sep 22, 2023

Rewiring tumor mitochondria enhances the immune system’s ability to recognize and fight cancer

Posted by in category: biotech/medical

Immunotherapy, which uses the body’s own immune system to fight cancer, is an effective treatment option, yet many patients do not respond to it. Thus, cancer researchers are seeking new ways to optimize immunotherapy so that it is more effective for more people.

Now, Salk Institute scientists have found that manipulating an early step in in mitochondria—the cell’s powerhouses—reduces melanoma growth and enhances the in mice.

The study, published in Science on September 21, 2023, revealed that when electrons take one of two initial routes through mitochondria, genes and proteins become activated that are needed for to recognize and kill .

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