Anosognosia is a condition in which a patient is unaware of their neurological deficit or psychiatric condition. Visual anosognosia, also called Anton syndrome, is associated with complete cortical blindness and unawareness of vision loss.
Researchers from Brigham and Women’s Hospital, a founding member of the Mass General Brigham healthcare system, sought to identify brain network connections associated with anosognosia. The investigators analyzed the connectivity patterns of 267 lesion locations associated with either vision loss (with and without awareness) or weakness (with and without awareness).
Researchers used a recently validated technique termed lesion network mapping to test whether these lesion-induced deficits map to specific brain networks. They were able to identify distinct network connections associated with visual anosognosia and motor anosognosia as well as a shared network for awareness of these deficits.
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