Mar 3, 2023

Molecular atlas of spider silk production could help bring unparalleled material to market

Posted by in categories: biotech/medical, materials

Researchers from Southwest University in China have constructed the entire chromosomal-scale genome assembly and complete spidroin gene set of the golden orb-weaving spider, Trichonephila clavata, known for its especially strong, golden-colored webs.

They attest that their work “Provides multidimensional data that significantly expand the knowledge of spider dragline silk generation…” and the researchers plan on using this new “molecular atlas” to better understand how spiders manufacture their silk.

Published in the journal Nature Communications, the paper details the steps the researchers took, from wild spider capture to multiomic analysis, in revealing the interplay of genes within the spider’s major ampullate gland, the gland responsible for producing dragline silk.

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