Researchers have used fruit flies to decipher an unexplained connection between Alzheimer’s disease and a genetic variation, revealing that it causes neurons to die.
The findings from the Walter and Eliza Hall Institute (WEHI)-led team uncover a possible cause of neurodegeneration in the early stages of Alzheimer’s disease and open the door for the future development of new treatments for cognitive diseases.
The study, “An increase in mitochondrial TOM activates apoptosis to drive retinal neurodegeneration,” with collaborators from Australian National University, is published in Scientific Reports.
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