A recent review published in the Journal of Autoimmunity discussed the applications of single-cell ribonucleic acid sequencing (scRNA-seq) in understanding autoimmune disorders.
The review comprehensively covered the principles, procedures, and sequencing platforms used in scRNA-seq, and explored its use in understanding the mechanisms of nine systemic and 32 organ-specific autoimmune and autoinflammatory diseases.
Autoimmune diseases (AID) are a complex phenomenon involving various types of cells. The diseases occur when the body’s immune system fails to recognize its cells and components and launches an immune response against them. Autoimmune diseases are broadly divided into organ-specific and non-organ-specific AID.
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