Rhesus macaques don’t monkey around when it comes to HIV; they have a protein that effectively disables invading HIV particles.
A group of University of Chicago scientists announced an innovative study that explains how the macaques’ immune protein, called TRIM5α, works its magic. It also represents a significant step forward in the science of modeling how complex biological proteins assemble themselves, the scientists said.
“These proteins work together to encase the HIV capsid in a hexagonal net and restrict viral activity,” said postdoctoral fellow Alvin Yu and lead author of the study, which was published in Nature Communications.
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